{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T23:05:58Z","timestamp":1787699158797,"version":"build-2784847793"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1982,2,1]],"date-time":"1982-02-01T00:00:00Z","timestamp":381369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1982,2,1]],"date-time":"1982-02-01T00:00:00Z","timestamp":381369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1982,2]]},"DOI":"10.1136\/ard.41.1.69","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"69-73","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Antibody to intermediate filaments of the cytoskeleton."],"prefix":"10.1016","volume":"41","author":[{"given":"O.A","family":"Osung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.J","family":"Holborow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/S0140-6736(65)92505-5","article-title":"Antibody to smooth muscle in patients with liver disease","volume":"ii:","author":"D, Johnson G.","year":"1965","unstructured":"Johnson G D, Holborow E J, Glynn L E. Antibody to smooth muscle in patients with liver disease. Lancet 1965; ii: 878-9.","journal-title":"Lancet"},{"key":"ref_2","first-page":"473","article-title":"Human smooth muscle autoantibody. Its identification as antiactin antibody and a study of its binding to non-muscular cells","volume":"72","author":"Gabbiani, G.; B, Ryan G.; P, Lamelin J.","year":"1973","unstructured":"Gabbiani G, Ryan G B, Lamelin J P, et al. Human smooth muscle autoantibody. Its identification as antiactin antibody and a study of its binding to non-muscular cells. Am JPath 1973; 72: 473-88.","journal-title":"Am JPath"},{"key":"ref_3","first-page":"266","article-title":"Anti-actin specificity of human smooth muscle antibodies in chronic active hepatitis. Clin Exp Immunol","volume":"24","author":"Lidman, K.; Biberfeld, G.; Fagraeus, A.","year":"1976","unstructured":"Lidman K, Biberfeld G, Fagraeus A, et al. Anti-actin specificity of human smooth muscle antibodies in chronic active hepatitis. Clin Exp Immunol 1976; 24: 266-72."},{"key":"ref_4","first-page":"227","article-title":"Autoantibody to microtubules in infectious mononucleosis","volume":"17","author":"MA, Whitehouse J.; N, Ferguson; A, Currie G.","year":"1974","unstructured":"Whitehouse J MA, Ferguson N, Currie G A. Autoantibody to microtubules in infectious mononucleosis. Clin Exp Immunol 1974; 17: 227-35.","journal-title":"Clin Exp Immunol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0022-1759(79)90191-1","article-title":"Measurement of antibodies to tubulin by radioimmunoassay","volume":"28","author":"M, Mead G.; P, Cowin; A, Whitehouse J.M.","year":"1979","unstructured":"Mead G M, Cowin P, Whitehouse J M A. Measurement of antibodies to tubulin by radioimmunoassay. J Immunol Methods 1979; 28: 243-54.","journal-title":"J Immunol Methods"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/268240a0","article-title":"Human smooth muscle autoantibodies reacting with intermediate (IoOA) filaments","volume":"268","author":"Kurki, P.; Linder, E.; Virtanen, I.; Stenman, S.","year":"1977","unstructured":"Kurki P, Linder E, Virtanen I, Stenman S. Human smooth muscle autoantibodies reacting with intermediate (IoOA) filaments. Nature 1977; 268: 240-1.","journal-title":"Nature"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0090-1229(78)90165-4","article-title":"Characterisation of human smooth muscle autoantibodies reacting with cytoplasmic intermediate filaments","volume":"11","author":"Kurki, P.; Virtanen, I.; Stenman, S.; Linder, E.","year":"1978","unstructured":"Kurki P, Virtanen I, Stenman S, Linder E. Characterisation of human smooth muscle autoantibodies reacting with cytoplasmic intermediate filaments. Clin Immunol Immunopathol 1978; 11: 379-87.","journal-title":"Clin Immunol Immunopathol"},{"key":"ref_8","first-page":"76","article-title":"Viral infections and IgM autoantibodies to cytoplasmic intermediate filaments. Clin Exp Immunol","volume":"27","author":"H, Toh B.; A, Yildiz; J, Sotelo","year":"1979","unstructured":"Toh B H, Yildiz A, Sotelo J, et al. Viral infections and IgM autoantibodies to cytoplasmic intermediate filaments. Clin Exp Immunol 1979; 27: 76-81."},{"key":"ref_9","first-page":"279","article-title":"Smooth muscle autoantibodies reacting with cytoplasmic intermediate filaments in sera from normal, nonimmunised rabbits","volume":"19","year":"1980","unstructured":"Yildiz A, Toh B H, Sotelo J, Osung 0 A, Holborow E J. Smooth muscle autoantibodies reacting with cytoplasmic intermediate filaments in sera from normal, nonimmunised rabbits. Clin Immunol Immunopathol 1980; 19: 279-86.","journal-title":"Clin Immunol Immunopathol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/283249a0","article-title":"Intermediate filaments as mechanical integrators of cellular space","volume":"283","author":"Lazarides, E.","year":"1980","unstructured":"Lazarides E. Intermediate filaments as mechanical integrators of cellular space. Nature 1980; 283: 249-56.","journal-title":"Nature"},{"issue":"12","key":"ref_11","article-title":"Antibodies against two types of cytoskeletal intermediate sized flaments in sera for patients with rheumatoid arthritis. IX European Congress of Rheumatology. Abstract No 801","volume-title":"Immunofluorescence microscopical demonstration of antibodies against the cytoskeleton using cultured cells and foetal tissues as substrates. 4th International Congress of Immunology. Abstract 19.3.03","volume":"177","author":"Linder, E.; Hormia, M.; Wafin, F.; Isomaka, H.; V-0, Lehto; Stenman, S.","year":"1979","unstructured":"Linder E, Hormia M, Wafin F, Isomaka H, Lehto V-0, Stenman S. Antibodies against two types of cytoskeletal intermediate sized flaments in sera for patients with rheumatoid arthritis. IX European Congress of Rheumatology. Abstract No 801. 1979: 177 12 Linder E, Lehto V P, Kurki P, Stenman S. Immunofluorescence microscopical demonstration of antibodies against the cytoskeleton using cultured cells and foetal tissues as substrates. 4th International Congress of Immunology. Abstract 19.3.03. 1980."},{"key":"ref_12","first-page":"244","article-title":"Contractile proteins as autoantigens. Methods Achiev Exp Pathol","volume":"9","author":"J, Holborow E.","year":"1979","unstructured":"Holborow E J. Contractile proteins as autoantigens. Methods Achiev Exp Pathol 1979; 9: 244-60."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0022-1759(80)90103-9","article-title":"Immunoperoxidase EM localisation of cytoplasmic actin in cultured fibroblasts","volume":"34","author":"Osung 0 A, Toh B H, Gray A","year":"1980","unstructured":"Osung 0 A, Toh B H, Gray A, et al. Immunoperoxidase EM localisation of cytoplasmic actin in cultured fibroblasts. J Immunol Methods 1980; 34: 303-14.","journal-title":"J Immunol Methods"},{"key":"ref_14","first-page":"461","article-title":"in original serum","volume":"9","year":"1979","unstructured":"in original serum. ScandJ Immunol 1979; 9: 461-6.","journal-title":"ScandJ Immunol"},{"key":"ref_15","article-title":"Mrs PAH: A simple microtitre plate test for rheumatoid factors of different isotypes","author":"March, R.; Reeback, J.; J, Holborow E.; A, Coombs R.R.","unstructured":"March R, Reeback J, Holborow E J, Coombs R R A. Mrs PAH: A simple microtitre plate test for rheumatoid factors of different isotypes. J Immunol Methods in press.","journal-title":"J Immunol Methods"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"5034","DOI":"10.1073\/pnas.75.10.5034","article-title":"Different intermediate sized filaments distinguished by immunofluorescent microscopy","volume":"75","author":"W, Franke W.; E, Schmid; M, Osborn; K, Weber","year":"1978","unstructured":"Franke W W, Schmid E, Osborn M, Weber K. Different intermediate sized filaments distinguished by immunofluorescent microscopy. Proc Natl Acad Sci USA 1978; 75: 5034-8.","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1136\/jcp.29.5.403","article-title":"Classification of smooth muscle autoantibodies detected by immunofluorescence","volume":"29","author":"F, Bottazzo G.; A, Florin-Christensen; A, Fairfax; G, Swana; D, Doniach; V, Groeschel-Stewart","year":"1976","unstructured":"Bottazzo G F, Florin-Christensen A, Fairfax A, Swana G, Doniach D, Groeschel-Stewart V. Classification of smooth muscle autoantibodies detected by immunofluorescence. J Clin Pathol 1976; 29: 403-10.","journal-title":"J Clin Pathol"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0014-4835(76)90159-7","article-title":"Microtubules and microfilaments of bovine lens epithelial cells. Electron microscopy and immunofluorescence staining with specific antibodies","volume":"23","year":"1976","unstructured":"Lonchampt M 0, Laurent M, Courtois Y, Trenchev P, Hughes R C. Microtubules and microfilaments of bovine lens epithelial cells. Electron microscopy and immunofluorescence staining with specific antibodies. Exp. Eye Res 1976; 23: 505-18.","journal-title":"Exp. Eye Res"},{"key":"ref_19","first-page":"3894","article-title":"Co-existence of desmin and the fibroblastic intermediate filament subunit in muscle and non-muscle cells","volume-title":"Identification and comparative peptide analysis. Proc Natl Acad Sci","volume":"76","author":"L, Gard D.; B, Bell P.; E, Lazarides","year":"1979","unstructured":"Gard D L, Bell P B, Lazarides E. Co-existence of desmin and the fibroblastic intermediate filament subunit in muscle and non-muscle cells. Identification and comparative peptide analysis. Proc Natl Acad Sci USA 1979; 76: 3894-8."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0014-4827(79)90418-X","article-title":"Widespread occurrence of intermediate sized filaments of the vimentin type in cultured cells from diverse vertebrates","volume":"123","author":"W, Franke W.; E, Schmid; S, Winter; M, Osborn; K, Weber","year":"1979","unstructured":"Franke W W, Schmid E, Winter S, Osborn M, Weber K. Widespread occurrence of intermediate sized filaments of the vimentin type in cultured cells from diverse vertebrates. Exp Cell Res 1979; 123: 25-46.","journal-title":"Exp Cell Res"},{"key":"ref_21","first-page":"481","article-title":"Smooth muscle autoantibodies, viral infections","volume-title":"and malignant disease. Proc R Soc Med","volume":"65","author":"J, Holborow E.","year":"1972","unstructured":"Holborow E J. Smooth muscle autoantibodies, viral infections and malignant disease. Proc R Soc Med 1972; 65: 481."},{"key":"ref_22","first-page":"22","article-title":"Smooth muscle antibodies and other tissue antibodies in cytomegalovirus infection. Clin Exp Immunol","volume":"22","author":"Andersen, P.; K, Andersen H.","year":"1975","unstructured":"Andersen P, Andersen H K. Smooth muscle antibodies and other tissue antibodies in cytomegalovirus infection. Clin Exp Immunol 1975; 22: 22-9."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1136\/jcp.32.12.1257","article-title":"Mechanisms of smooth muscle antibody production-a clinical study in children with infections, haemolytic syndromes and idiopathic thrombocytopaenic purpura","volume":"32","author":"Kanakoudi-Tsakalidis, F.; Cassimos, C.; PapastavrouMaroudi, T.","year":"1979","unstructured":"Kanakoudi-Tsakalidis F, Cassimos C, PapastavrouMaroudi T, et al. Mechanisms of smooth muscle antibody production-a clinical study in children with infections, haemolytic syndromes and idiopathic thrombocytopaenic purpura. J Clin Pathol 1979; 32: 1257-63.","journal-title":"J Clin Pathol"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0090-1229(79)90093-X","article-title":"Autoantibody to 'intermediate filaments' in infectious mononucleosis","volume":"14","author":"Linder, E.; Kurki, P.; C, Andersson L.","year":"1979","unstructured":"Linder E, Kurki P, Andersson L C. Autoantibody to 'intermediate filaments' in infectious mononucleosis. Clin Immunol Immunopathol 1979; 14: 411-7.","journal-title":"Clin Immunol Immunopathol"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1093\/oxfordjournals.bmb.a071343","article-title":"Self-tolerance and autoimmunity","volume":"32","author":"C, Allison A.; M, Denman A.","year":"1976","unstructured":"Allison A C, Denman A M. Self-tolerance and autoimmunity. Br Med Bull 1976; 32: 124-9.","journal-title":"Br Med Bull"},{"key":"ref_26","first-page":"621","article-title":"Smooth muscle autoantibodies and autoantigens. Clin Exp Immunol","volume":"32","author":"H, Toh B.","year":"1980","unstructured":"Toh B H. Smooth muscle autoantibodies and autoantigens. Clin Exp Immunol 1980; 32: 621-8."}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724137922?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724137922?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.41.1.69","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T06:25:27Z","timestamp":1737527127000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724137922"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,2]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1982,2]]}},"alternative-id":["S0003496724137922"],"URL":"https:\/\/doi.org\/10.1136\/ard.41.1.69","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[1982,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antibody to intermediate filaments of the cytoskeleton.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.41.1.69","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1982 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}