{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T13:23:43Z","timestamp":1791120223592,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1984,4,1]],"date-time":"1984-04-01T00:00:00Z","timestamp":449625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1984,4,1]],"date-time":"1984-04-01T00:00:00Z","timestamp":449625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1984,4]]},"DOI":"10.1136\/ard.43.2.151","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"151-156","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Impaired polymorphonuclear leucocyte chemotaxis in rheumatoid arthritis."],"prefix":"10.1016","volume":"43","author":[{"given":"D.H","family":"Goddard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.P","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.R","family":"Kirwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.D","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.J","family":"Holborow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1172\/JCI106754","article-title":"Chemotaxis of polymorphonuclear leucocytes from patients with rheumatoid arthritis","volume":"50","author":"G, Mowat A.; J, Baum","year":"1971","unstructured":"Mowat A G, Baum J. Chemotaxis of polymorphonuclear leucocytes from patients with rheumatoid arthritis.J Clin Invest 1971; 50: 2541-4.","journal-title":"J Clin Invest"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1136\/ard.35.6.510","article-title":"Defective responsiveness of ascorbic acid of neutrophil random and chemotactic migration in Felty's syndrome and systemic lupus erythematosus","volume":"35","author":"J, Goetzl E.","year":"1976","unstructured":"Goetzl E J. Defective responsiveness of ascorbic acid of neutrophil random and chemotactic migration in Felty's syndrome and systemic lupus erythematosus. Ann Rheum Dis 1976; 35: 510-5.","journal-title":"Ann Rheum Dis"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1136\/ard.39.1.68","article-title":"Defective polymorphonuclear leucocyte chemotaxis in rheumatoid arthritis associated with a serum inhibitor","volume":"39","author":"M, Hanlon S.; S, Panayai G.; R, Laurent","year":"1980","unstructured":"Hanlon S M, Panayai G S, Laurent R. Defective polymorphonuclear leucocyte chemotaxis in rheumatoid arthritis associated with a serum inhibitor. Ann Rheum Dis 1980; 39: 68-74.","journal-title":"Ann Rheum Dis"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1136\/ard.40.4.370","article-title":"Polymorphonuclear cell function in rheumatoid arthritis and Felty's syndrome","volume":"40","author":"B, Howe G.; N, Fordham J.; A, Brown K.; F, Currey H.L.","year":"1981","unstructured":"Howe G B, Fordham J N, Brown K A, Currey H L F. Polymorphonuclear cell function in rheumatoid arthritis and Felty's syndrome. Ann Rhewn Dis 1981; 40: 370-5.","journal-title":"Ann Rhewn Dis"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1056\/NEJM197204062861401","article-title":"Defective chemotaxis associated with a serum inhibitor in cirrhotic patients","volume":"286","author":"N, DeMeo A.; R, Anderson B.","year":"1972","unstructured":"DeMeo A N, Anderson B R. Defective chemotaxis associated with a serum inhibitor in cirrhotic patients. N Engl J Med 1972; 286: 735-40.","journal-title":"N Engl J Med"},{"key":"ref_6","first-page":"878","article-title":"A serum inhibitor of leucotaxis in a child with recurrent infections","volume":"79","author":"W, Smith C.; C, Hollers J.; E, Dupree","year":"1972","unstructured":"Smith C W, Hollers J C, Dupree E, et al. A serum inhibitor of leucotaxis in a child with recurrent infections. J Lab Clin Med 1972; 79: 878-85.","journal-title":"J Lab Clin Med"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1056\/NEJM197401102900203","article-title":"Defective regulators of inflammatory mediators in Hodgkin's disease. Supernormal levels of chemotactic factor inactivator","volume":"290","author":"A, Ward P.; L, Berenberg J.","year":"1974","unstructured":"Ward P A, Berenberg J L. Defective regulators of inflammatory mediators in Hodgkin's disease. Supernormal levels of chemotactic factor inactivator. N Engl J Med 1974; 290: 76-80.","journal-title":"N Engl J Med"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"189","DOI":"10.4049\/jimmunol.113.1.189","article-title":"Characterisation of serum inhibitors of neutrophil chemotaxis associated with anergy","volume":"113","author":"E, Van Epps D.; L, Palmer D.; Jnr, Williams R.C.","year":"1974","unstructured":"Van Epps D E, Palmer D L, Williams R C Jnr. Characterisation of serum inhibitors of neutrophil chemotaxis associated with anergy. J Immunol 1974; 113: 189-200.","journal-title":"J Immunol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/0002-9343(75)90354-X","article-title":"Inhibitors of leucocyte chemotaxis in alcoholic liver disease","volume":"59","author":"E, Van Epps D.; G, Strickland R.; Jnr, Williams R.C.","year":"1975","unstructured":"Van Epps D E, Strickland R G, Williams R C Jnr. Inhibitors of leucocyte chemotaxis in alcoholic liver disease. Am J Med 1975; 59: 200-7.","journal-title":"Am J Med"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"414","DOI":"10.7326\/0003-4819-84-4-414","article-title":"dysfunction in sarcoidosis","volume":"84","author":"G, Maderazo E.","year":"1976","unstructured":"Maderazo E G, Ward P A, Woronick C L, et al. Leucocyte dysfunction in sarcoidosis. Ann Intern Med 1976; 84: 414-9.","journal-title":"Ann Intern Med"},{"key":"ref_11","first-page":"1025","article-title":"Defective leucotaxis in patients with lepromatous leprosy","volume":"87","author":"A, Ward P.; S, Goralnick; E, Bullock W.","year":"1976","unstructured":"Ward P A, Goralnick S, Bullock W E. Defective leucotaxis in patients with lepromatous leprosy. J Lab Clin Med 1976; 87: 1025-32.","journal-title":"J Lab Clin Med"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF00541267","article-title":"Immunoglobulin inclusions in rheumatoid arthritis polymorphonuclear cells: lack of correlation with circulating immune complexes","volume":"2","author":"H, Goddard D.; A, Brown K.; P, Kirk A.; D, McCarthy; D, Johnson G.; J, Holborow E.","year":"1982","unstructured":"Goddard D H, Brown K A, Kirk A P, McCarthy D, Johnson G D, Holborow E J. Immunoglobulin inclusions in rheumatoid arthritis polymorphonuclear cells: lack of correlation with circulating immune complexes. Rheumatol Int 1982; 2: 27-30.","journal-title":"Rheumatol Int"},{"key":"ref_13","first-page":"175","article-title":"Revision of diagnostic criteria for rheumatoid arthritis","volume":"9","author":"W, Ropes M.; A, Bennett G.; S, Cobb","year":"1958","unstructured":"Ropes M W, Bennett G A, Cobb S, et al. Revision of diagnostic criteria for rheumatoid arthritis. Bull Rheum Dis 1958; 9: 175-6.","journal-title":"Bull Rheum Dis"},{"key":"ref_14","first-page":"713","article-title":"Characterisation of lactic dehydrogenase of normal human granulocytes","volume":"61","author":"Dioguardi, N.; Agostini, A.; Fiorelli, G.; Lomanto, B.","year":"1963","unstructured":"Dioguardi N, Agostini A, Fiorelli G, Lomanto B. Characterisation of lactic dehydrogenase of normal human granulocytes. J Lab Clin med 1963; 61: 713-25.","journal-title":"J Lab Clin med"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1084\/jem.137.2.387","article-title":"Leucocyte locomotion and chemotaxis. New methods for evaluation and demonstration of cell-derived chemotactic factors","volume":"137","author":"H, Zigmond S.; G, Hirsch J.","year":"1973","unstructured":"Zigmond S H, Hirsch J G. Leucocyte locomotion and chemotaxis. New methods for evaluation and demonstration of cell-derived chemotactic factors. J Exp Med 1973; 137: 387-410.","journal-title":"J Exp Med"},{"key":"ref_16","first-page":"280","article-title":"Differential immunofluorescence staining of polymorphonuclear leucocytes for discrimination between surface bound and internalised immunoglobulin","volume":"0","author":"D, Johnson G.; H, Goddard D.; J, Holborow E.","year":"1982","unstructured":"Johnson G D, Goddard D H, Holborow E J. Differential immunofluorescence staining of polymorphonuclear leucocytes for discrimination between surface bound and internalised immunoglobulin. J Immunol Methods 1982; S0: 280.","journal-title":"J Immunol Methods"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0022-1759(72)90006-3","article-title":"The conjugation of immunoglobulins with tetramethylrhodamine isthiocynate: a comparison between amorphous and crystalline fluorochrome","volume":"1","author":"Amante, L.; Ancona, A.; Forni, L.","year":"1972","unstructured":"Amante L, Ancona A, Forni L. The conjugation of immunoglobulins with tetramethylrhodamine isthiocynate: a comparison between amorphous and crystalline fluorochrome. J Immunol Methods 1972; 1: 289-301.","journal-title":"J Immunol Methods"},{"key":"ref_18","first-page":"1","article-title":"The formation of immunoglobulins by human tissues in vitro-the methods and their specificity","volume":"11","author":"R, Van Furth; E, Schmit H.R.; H, Hijmans","year":"1966","unstructured":"Van Furth R, Schmit H R E, Hijmans H. The formation of immunoglobulins by human tissues in vitro-the methods and their specificity. Immunology 1966; 11: 1-15.","journal-title":"Immunology"},{"key":"ref_19","first-page":"15","volume-title":"Handbook of experimental immunology","author":"D, Johnson G.","year":"1978","unstructured":"Johnson G D, Holborow E J, Dorling J. In: Weir D M, ed. Handbook of experimental immunology. Oxford: Blackwell, 1978: 15-7."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0022-1759(81)90183-6","article-title":"A simple method of reducing the fading of immunofluorescence during microscopy","volume":"43","author":"D, Johnson G.; M, Araujo G.","year":"1981","unstructured":"Johnson G D, Araujo G M. A simple method of reducing the fading of immunofluorescence during microscopy. J Immunol Methods 1981; 43: 349-50.","journal-title":"J Immunol Methods"},{"key":"ref_21","first-page":"457","article-title":"Effects of human IgG on locomotion of human neutrophils related to IgG binding of a hydrophobic probe","volume":"4","author":"C, Wilkinson P.","year":"1980","unstructured":"Wilkinson P C. Effects of human IgG on locomotion of human neutrophils related to IgG binding of a hydrophobic probe. Immunology 1980; 4: 457.","journal-title":"Immunology"},{"key":"ref_22","first-page":"641","article-title":"Chemotaxis in leucocytes","volume":"35","author":"U, Keller H.; E, Sorkin","year":"1968","unstructured":"Keller H U, Sorkin E. Chemotaxis in leucocytes. Experientia 1968; 35: 641-52.","journal-title":"Experientia"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1136\/ard.43.2.146","article-title":"Changes in normal polymorphonuclear leucocyte motility after ingestion of IgG aggregates","volume":"43","author":"D, G.; J, Holborow E.","year":"1984","unstructured":"G D, Holborow E J. Changes in normal polymorphonuclear leucocyte motility after ingestion of IgG aggregates. Ann Rheum Dis 1984; 43: 146-150.","journal-title":"Ann Rheum Dis"},{"key":"ref_24","first-page":"239","article-title":"Book review Recent Advances in Rheumatology","volume":"3","author":"Dick, W.Carson","year":"1983","unstructured":"Book review Recent Advances in Rheumatology. No. 3. Eds. W. Carson Dick and J. M. H. Moll. Pp. 239. \u00a324-00. Churchill Livingstone: Edinburgh. 1983.","journal-title":"No"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724132980?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724132980?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.43.2.151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T06:19:26Z","timestamp":1738304366000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724132980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,4]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1984,4]]}},"alternative-id":["S0003496724132980"],"URL":"https:\/\/doi.org\/10.1136\/ard.43.2.151","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[1984,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impaired polymorphonuclear leucocyte chemotaxis in rheumatoid arthritis.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.43.2.151","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1984 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}