{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T05:13:04Z","timestamp":1737609184931,"version":"3.33.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1989,4,1]],"date-time":"1989-04-01T00:00:00Z","timestamp":607392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1989,4,1]],"date-time":"1989-04-01T00:00:00Z","timestamp":607392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1989,4]]},"DOI":"10.1136\/ard.48.4.295","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"295-301","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["HLA class II DR, DQ, and DP restriction fragment length polymorphisms in rheumatoid arthritis."],"prefix":"10.1016","volume":"48","author":[{"given":"W.M","family":"Howell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.R","family":"Evans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.J","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.I","family":"Cawley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"ref_1","article-title":"HLA and disease associations","author":"Tiwari, J.; Terasaki, P.","year":"1985","unstructured":"Tiwari J, Terasaki P. HLA and disease associations. New York: Springer, 1985."},{"key":"ref_2","first-page":"129","article-title":"Study of HLA antigens in ten multiple-case rheumatoid arthritis families","volume":"11","author":"Nunez, G.; E, Moore S.; V, Ball G.; R, Hurd E.; Stastny, P.","year":"1984","unstructured":"Nunez G, Moore S E, Ball G V, Hurd E R, Stastny P. Study of HLA antigens in ten multiple-case rheumatoid arthritis families. J Rheumatol 1984; 11: 129-35.","journal-title":"J Rheumatol"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1399-0039.1986.tb01499.x","article-title":"Genetics of rheumatoid arthritis","volume":"27","author":"Payami, H.; Thomson, G.; A, Kahn M.","year":"1986","unstructured":"Payami H, Thomson G, Kahn M A, et al. Genetics of rheumatoid arthritis. Tissue Antigens 1986; 27: 57-63.","journal-title":"Tissue Antigens"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00915418","article-title":"The molecular basis for HLA class II associations with rheumatoid arthritis","volume":"7","author":"T, Nepom G.; A, Hansen J.; S, Nepom B.","year":"1987","unstructured":"Nepom G T, Hansen J A, Nepom B S. The molecular basis for HLA class II associations with rheumatoid arthritis. J Clin Immunol 1987; 7: 1-7.","journal-title":"J Clin Immunol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0198-8859(87)90044-9","article-title":"HLA DQa and DQOf restriction fragment length polymorphisms associated with Felty's syndrome and DR4-positive rheumatoid arthritis","volume":"19","author":"M, Sansom D.; L, Bidwell J.; J, Maddison P.; G, Campion; T, Klouda P.; A, Bradley B.","year":"1987","unstructured":"Sansom D M, Bidwell J L, Maddison P J, Campion G, Klouda P T, Bradley B A. HLA DQa and DQOf restriction fragment length polymorphisms associated with Felty's syndrome and DR4-positive rheumatoid arthritis. Hum Immunol 1987; 19: 269-78.","journal-title":"Hum Immunol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1136\/jcp.40.9.948","article-title":"The HLA system: structure and function","volume":"40","author":"F, Bodmer W.","year":"1987","unstructured":"Bodmer W F. The HLA system: structure and function. J Clin Pathol 1987; 40: 948-58.","journal-title":"J Clin Pathol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1016\/0161-5890(86)90009-X","article-title":"HLA-DR allogenotyping using exonspecific cDNA probes and application of rapid minigel methods","volume":"23","author":"L, Bidwell J.; A, Jarrold E.","year":"1986","unstructured":"Bidwell J L, Jarrold E A. HLA-DR allogenotyping using exonspecific cDNA probes and application of rapid minigel methods. Mol Immunol 1986; 23: 1111-6.","journal-title":"Mol Immunol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/308327a0","article-title":"Isotypic and allotypic variation of human class II histocompatibility antigen a-chain genes","volume":"308","author":"Auffray, C.; W, Lillie J.; Arnot, D.; Grossberger, D.; Kappes, D.; L, Strominger J.","year":"1984","unstructured":"Auffray C, Lillie J W, Arnot D, Grossberger D, Kappes D, Strominger J L. Isotypic and allotypic variation of human class II histocompatibility antigen a-chain genes. Nature 1984; 308: 327-33.","journal-title":"Nature"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"3687","DOI":"10.1073\/pnas.79.12.3687","article-title":"Complete amino acid sequence of an HLA-DR antigen-like, l chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B","volume":"79","author":"Larhammar, D.; Schenning, L.; Gustafsson, K.","year":"1982","unstructured":"Larhammar D, Schenning L, Gustafsson K, et al. Complete amino acid sequence of an HLA-DR antigen-like,l chain as predicted from the nucleotide sequence: similarities with immunoglobulins and HLA-A, -B and -C antigens. Proc Natl Acad Sci USA 1982; 79: 3687-91.","journal-title":"and -C antigens. Proc Natl Acad Sci USA"},{"key":"ref_10","first-page":"3025","article-title":"Analysis by molecular cloning of the human class","volume-title":"II genes. Fed Proc","volume":"43","author":"Erlich, H.; Stetler, D.; Shang-Dong, R.; Saiki, R.","year":"1984","unstructured":"Erlich H, Stetler D, Shang-Dong R, Saiki R. Analysis by molecular cloning of the human class II genes. Fed Proc 1984; 43: 3025-30."},{"key":"ref_11","first-page":"6036","article-title":"Genetic mapping of a human class II antigen 5-chain cDNA clone to the SB region","volume-title":"of the HLA complex. Proc Natl Acad Sci","volume":"80","author":"Roux-Dosseto, M.; Auffray, C.; W, Lille J.","year":"1983","unstructured":"Roux-Dosseto M, Auffray C, Lille J W, et al. Genetic mapping of a human class II antigen 5-chain cDNA clone to the SB region of the HLA complex. Proc Natl Acad Sci USA 1983; 80: 6036-40."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/0003-2697(84)90381-6","article-title":"A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity","volume":"137","author":"P, Feinberg A.; B, Vogelstein","year":"1984","unstructured":"Feinberg A P, Vogelstein B. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1984; 137: 266-7.","journal-title":"Anal Biochem"},{"key":"ref_13","first-page":"6970","article-title":"Use of pooled DNA samples to detect linkage disequilibrium of polymorphic restriction fragments and human disease: studies of the HLA","volume-title":"class II loci. Proc Natl Acad Sci","volume":"82","author":"Arnheim, N.; Strange, C.; Erlich, H.","year":"1985","unstructured":"Arnheim N, Strange C, Erlich H. Use of pooled DNA samples to detect linkage disequilibrium of polymorphic restriction fragments and human disease: studies of the HLA class II loci. Proc Natl Acad Sci USA 1985; 82: 6970-4."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0022-2836(75)80083-0","article-title":"Detection of specific sequences among DNA fragments separated by gel electrophoresis","volume":"98","author":"M, Southern E.","year":"1975","unstructured":"Southern E M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 1975; 98: 503-17.","journal-title":"J Mol Biol"},{"article-title":"DR antigens in the British Isles. UK Transplant Service Report","year":"1985","key":"ref_15","unstructured":"Klouda P T, Molnar J, Wasik A, Bodmer J G. HLA-A, B and DR antigens in the British Isles. UK Transplant Service Report. November 1985."},{"key":"ref_16","first-page":"243","article-title":"LB and TA10 specificities of ninth workshop homozygous typing cells","author":"T, Schreuder G.M.; I, Doxiadis; J, Parlevliet; HLA-DR, Grosse-Wilde H.; D.Q.","year":"1984","unstructured":"Schreuder G M T, Doxiadis I, Parlevliet J, Grosse-Wilde H. HLA-DR, DQ, LB and TA10 specificities of ninth workshop homozygous typing cells. In: Albert E D, Baur M P, Mayr W R, eds. Histocompatibility testing 1984. Berlin: Springer, 1984: 243-8."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1136\/ard.45.8.627","article-title":"HLA and rheumatoid arthritis: combined analysis of 440 British patients","volume":"45","author":"Jaraquemada, D.; Ollier, W.; Awad, J.","year":"1986","unstructured":"Jaraquemada D, Ollier W, Awad J. HLA and rheumatoid arthritis: combined analysis of 440 British patients. Ann Rheum Dis 1986; 45: 627-36.","journal-title":"Ann Rheum Dis"},{"key":"ref_18","first-page":"13","article-title":"Multiple HLA associations and disease susceptibility","volume":"4","author":"A, Sachs J.; R, Kirwan J.","year":"1986","unstructured":"Sachs J A, Kirwan J R. Multiple HLA associations and disease susceptibility. Dis Markers 1986; 4: 13-27.","journal-title":"Dis Markers"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1399-0039.1988.tb02068.x","article-title":"HLA-DP in rheumatoid arthritis","volume":"31","author":"Pawelec, G.; Reeker, P.; Brackentz, D.","year":"1988","unstructured":"Pawelec G, Reeker P, Brackentz D, et al. HLA-DP in rheumatoid arthritis. Tissue Antigens 1988; 31: 83-9.","journal-title":"Tissue Antigens"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1056\/NEJM197804202981602","article-title":"Association of the B-cell alloantigen DRw4 with rheumatoid arthritis","volume":"298","author":"Stastny, P.","year":"1978","unstructured":"Stastny P. Association of the B-cell alloantigen DRw4 with rheumatoid arthritis. N Engl J Med 1978; 298: 869-71.","journal-title":"N Engl J Med"},{"key":"ref_21","first-page":"1002","article-title":"Identification of HLA-Dw14 genes in DR4+ rheumatoid arthritis","volume":"ii:","author":"T, Nepom G.; E, Seyfried C.; L, Holbeck S.; R, Wilske K.; S, Nepom B.","year":"1986","unstructured":"Nepom G T, Seyfried C E, Holbeck S L, Wilske K R, Nepom B S. Identification of HLA-Dw14 genes in DR4+ rheumatoid arthritis. Lancet 1986; ii: 1002-4.","journal-title":"Lancet"},{"key":"ref_22","first-page":"1118","article-title":"HLA-DQ beta-chain polymorphism in HLA-DR4 haplotypes associated with rheumatoid arthritis","volume":"ii:","author":"P, Singal D.; B, Reid; B, Kassam Y.; M, D.'Souza; G, Bensen W.; D, Adachi J.","year":"1987","unstructured":"Singal D P, Reid B, Kassam Y B, D'Souza M, Bensen W G, Adachi J D. HLA-DQ beta-chain polymorphism in HLA-DR4 haplotypes associated with rheumatoid arthritis. Lancet 1987; ii: 1118-20.","journal-title":"Lancet"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1084\/jem.164.1.333","article-title":"An HLA-D region restriction fragment length polymorphism associated with celiac disease","volume":"164","author":"D, Howell M.; K, Austin R.; D, Kelleher; T, Nepom G.; F, Kagnoff M.","year":"1986","unstructured":"Howell M D, Austin R K, Kelleher D, Nepom G T, Kagnoff M F. An HLA-D region restriction fragment length polymorphism associated with celiac disease. J Exp Med 1986; 164: 333-8.","journal-title":"J Exp Med"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1007\/BF00430317","article-title":"DNA polymorphism related to HLA-DR2 Dw2 in patients with narcolepsy","volume":"22","author":"Marcadet, A.; Gebuhrer, L.; Betuel, H.","year":"1985","unstructured":"Marcadet A, Gebuhrer L, Betuel H, et al. DNA polymorphism related to HLA-DR2 Dw2 in patients with narcolepsy. Immunogenetics 1985; 22: 679-83.","journal-title":"Immunogenetics"},{"key":"ref_25","first-page":"126","article-title":"HLA-DQfi chain restriction fragments can differentiate between healthy and narcoleptic individuals with HLA-DR2","volume-title":"Immunogenetics","volume":"23","author":"Inoko, H.; Ando, A.; Tsuji, K.; Matsui, K.; Juji, T.; Honda, Y.","year":"1986","unstructured":"Inoko H, Ando A, Tsuji K, Matsui K, Juji T, Honda Y. HLA-DQfi chain restriction fragments can differentiate between healthy and narcoleptic individuals with HLA-DR2. Immunogenetics 1986; 23: 126-8."},{"key":"ref_26","first-page":"6542","article-title":"Detection of diseasespecific restriction fragment length polymorphisms in pemphigus vulgaris linked to the DQwl and DQw3 alleles","volume-title":"of the HLAD region. Proc Natl Acad Sci USA","volume":"84","author":"Szafer, F.; Brautbar, C.; Tzfoni, E.","year":"1987","unstructured":"Szafer F, Brautbar C, Tzfoni E, et al. Detection of diseasespecific restriction fragment length polymorphisms in pemphigus vulgaris linked to the DQwl and DQw3 alleles of the HLAD region. Proc Natl Acad Sci USA 1987; 84: 6542-5."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"941","DOI":"10.4049\/jimmunol.137.3.941","article-title":"Only one DQPi restriction fragment pattern of each DR specificity is associated with insulin-dependent diabetes","volume":"137","author":"Bohme, J.; Carlsson, B.; Wallin, J.","year":"1986","unstructured":"Bohme J, Carlsson B, Wallin J, et al. Only one DQPi restriction fragment pattern of each DR specificity is associated with insulin-dependent diabetes. J Immunol 1986; 137: 941-7.","journal-title":"J Immunol"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1172\/JCI112931","article-title":"Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ","volume":"79","author":"Michelson, B.; Lernmark, A.","year":"1987","unstructured":"Michelson B, Lernmark A. Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ. J Clin Invest 1987; 79: 1144-52.","journal-title":"J Clin Invest"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1038\/329599a0","article-title":"HLA-DQ,1 gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus","volume":"329","author":"Todd J A, Bell J I, McDevitt H 0","year":"1987","unstructured":"Todd J A, Bell J I, McDevitt H 0. HLA-DQ,1 gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 1987; 329: 599-604.","journal-title":"Nature"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000349672411062X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000349672411062X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.48.4.295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T05:30:51Z","timestamp":1737523851000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000349672411062X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,4]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1989,4]]}},"alternative-id":["S000349672411062X"],"URL":"https:\/\/doi.org\/10.1136\/ard.48.4.295","relation":{},"ISSN":["0003-4967"],"issn-type":[{"type":"print","value":"0003-4967"}],"subject":[],"published":{"date-parts":[[1989,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HLA class II DR, DQ, and DP restriction fragment length polymorphisms in rheumatoid arthritis.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.48.4.295","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1989 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}