{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:24:19Z","timestamp":1780471459874,"version":"3.54.1"},"reference-count":17,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[1990,12,1]],"date-time":"1990-12-01T00:00:00Z","timestamp":660009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1990,12,1]],"date-time":"1990-12-01T00:00:00Z","timestamp":660009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1990,12]]},"DOI":"10.1136\/ard.49.12.976","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"976-979","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["DQw7 and the C4B null allele in rheumatoid arthritis and Felty's syndrome."],"prefix":"10.1016","volume":"49","author":[{"given":"R","family":"Clarkson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.S","family":"Bate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M","family":"Grennan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Chattopadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0198-8859(87)90076-0","article-title":"Molecular compkxity of HLA-DQw3: the TalO determinant is lcted on a subaet of DRw3 B chains","volume":"18","author":"F, Radka S.; G, Scott R.; J, Stewart S.","year":"1987","unstructured":"Radka S F, Scott R G, Stewart S J. Molecular compkxity of HLA-DQw3: the TalO determinant is lcted on a subaet of DRw3 B chains. Hum Immwl 1987; 18: 287-300.","journal-title":"Hum Immwl"},{"key":"ref_2","first-page":"1118","article-title":"HLA-DQ DR4 hployes a beta-chain","author":"P, Singal D.; B, Reid; B, Kasam Y.; M, Souza; G, Benen W.; D, Adachi J.","year":"1987","unstructured":"Singal D P, Reid B, Kasam Y B, Souza M, Benen W G, Adachi J D. HLA-DQ DR4 hployes a beta-chain pol ted with r toid in HLAarthitis. Lance 1987: 1118-9.","journal-title":"Lance"},{"key":"ref_3","first-page":"1","article-title":"The molecular basis for HLA cla II associations with rheumatoid arthritis","volume-title":"I Clsn Immuol","volume":"7","author":"T, Nepom G.; A, Hanen J.; S, Nepom B.","year":"1987","unstructured":"Nepom G T, Hanen J A, Nepom B S. The molecular basis for HLA cla II associations with rheumatoid arthritis. I Clsn Immuol 1987; 7: 1-7."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1136\/ard.45.7.534","article-title":"Immunogenetic heterogeneity of rheumatoid arthritis","volume":"45","author":"L, Westedt M.; C, Breedveld F.; M, Schreuder G.; D, D.'Amoro J.; A, Cats; P, De Vries R.R.","year":"1986","unstructured":"Westedt M L, Breedveld F C, Schreuder G M, D'Amoro J D, Cats A, De Vries R R P. Immunogenetic heterogeneity of rheumatoid arthritis. Ann Rheum Dis 1986; 45: 534-8.","journal-title":"Ann Rheum Dis"},{"key":"ref_5","first-page":"990","article-title":"DQB polymorphism and genetic susceptibility to Felty's syndrome","volume":"31","author":"S, So A.K.; A, Warner C.; D, Sansm; J, Walport M.","year":"1988","unstructured":"So A K S, Warner C A, Sansm D, Walport M J. DQB polymorphism and genetic susceptibility to Felty's syndrome. Ardtiis Rheun 1988; 31: 990-4.","journal-title":"Ardtiis Rheun"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0198-8859(87)90044-9","article-title":"HLA DQ alpha and DQ beta restriction fragment lngth polymorphism associated with Fedy's syndrome and DR4-positive rheumatoid arthritis","volume":"19","author":"M, Sansom D.; L, Bidwell J.; J, Maddison P.; G, Campion; T, Klouda D.; A, Bradley B.","year":"1987","unstructured":"Sansom D M, Bidwell J L, Maddison P J, Campion G, Klouda D T, Bradley B A. HLA DQ alpha and DQ beta restriction fragment lngth polymorphism associated with Fedy's syndrome and DR4-positive rheumatoid arthritis. Hum Immunol 1987; 19: 269-79.","journal-title":"Hum Immunol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/art.1780310807","article-title":"Complment C4B-null alleles in Felty's syndrome","volume":"31","author":"Thomson, W.; A, Sanders P.; Davis, M.; Davidson, J.; A, Dyer P.; M, Grennan D.","year":"1988","unstructured":"Thomson W, Sanders P A, Davis M, Davidson J, Dyer P A, Grennan D M. Complment C4B-null alleles in Felty's syndrome. Arthitis Rhem 1988; 31: 984-9.","journal-title":"Arthitis Rhem"},{"key":"ref_8","first-page":"718","article-title":"A comparison of clinical and immunogenetic features in familial and sporadic rheumatoid arthritis","volume":"14","author":"A, Sanders P.; M, Grennan D.; A, Dyer P.; W, Thomson; G, De Lange","year":"1987","unstructured":"Sanders P A, Grennan D M, Dyer P A, Thomson W, De Lange G. A comparison of clinical and immunogenetic features in familial and sporadic rheumatoid arthritis. Rheumatol 1987; 14: 718-22.","journal-title":"Rheumatol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1136\/ard.18.1.49","article-title":"Dgnostc criteria for rheumatoid arthritis. 1958 revision","volume":"18","author":"W, Ropes M.","year":"1959","unstructured":"Ropes M W. Dgnostc criteria for rheumatoid arthritis. 1958 revision. Ann Rheum Dis 1959; 18: 49-53.","journal-title":"Ann Rheum Dis"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1097\/00007890-198803000-00027","article-title":"A DNA-RFLP typing system that positively identifies serologically well-defined and illdefined HLA-DR and DQ aldles, including DRw1O","volume":"45","author":"L, Bidwell J.; A, Bidwell E.; A, Savage D.; D, Middleton; T, Klouda P.; A, Bradley B.","year":"1988","unstructured":"Bidwell J L, Bidwell E A, Savage D A, Middleton D, Klouda P T, Bradley B A. A DNA-RFLP typing system that positively identifies serologically well-defined and illdefined HLA-DR and DQ aldles, including DRw1O. TranspLatation 1988; 45: 640-6.","journal-title":"TranspLatation"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1042\/bj2390763","article-title":"Phenotyping of human complement component C4, a class-Ill HLA antgen","volume":"239","author":"Sim, E.; J, Cross S.","year":"1986","unstructured":"Sim E, Cross S J. Phenotyping of human complement component C4, a class-Ill HLA antgen. BiochemJ 1986; 239: 763-7.","journal-title":"BiochemJ"},{"key":"ref_12","article-title":"Non-pa statinsics for the behaioal sciences","author":"Siegd, S.","year":"1956","unstructured":"Siegd S. Non-pa statinsics for the behaioal sciences. New York: McGraw-Hill, 1956."},{"key":"ref_13","first-page":"82","article-title":"of i_mune-assoiated genetic markers of human diseas","author":"genetics. In, Mathews J.D.H.L.A.","year":"1984","unstructured":"Mathews J D. HLA genetics. In: Simons M H, Tait B D, eds. Detecton of i_mune-assoiated genetic markers of human diseas. Edinburgh: Churchill Livingstone, 1984, 82-105."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/sim.4780020109","article-title":"The association between HLA anugens and the presence of certain diseases","volume":"2","author":"R, Green J.; M, Chiew; H, Low; J, Woodrow","year":"1983","unstructured":"Green J R, Chiew M, Low H, Woodrow J. The association between HLA anugens and the presence of certain diseases. Stat Med 1983; 2: 79-85.","journal-title":"Stat Med"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1002\/art.1780301102","article-title":"The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis","volume":"30","author":"Gregersen, P.; Silver, J.; Winchester, R.","year":"1987","unstructured":"Gregersen P, Silver J, Winchester R. The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthitis Rhewn 1987; 30: 1205-13.","journal-title":"Arthitis Rhewn"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1136\/ard.49.10.763","article-title":"Molecular characterisation of C4 null alleles found in Felty's syndrome","volume":"49","author":"C, Hifllarby M.; T, Strachan; M, Grennan D.","year":"1990","unstructured":"Hifllarby M C, Strachan T, Grennan D M. Molecular characterisation of C4 null alleles found in Felty's syndrome. Ann Rheum Dis 1990; 49: 763-7.","journal-title":"Ann Rheum Dis"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/BF00541352","article-title":"Felty's syndrome: autoimmune neutropenia or immunecomplex mediated disease","volume":"5","author":"C, Breedveld F.; M, Lafeber G.J.; G, Doeker; F, Claus; A, Cats","year":"1985","unstructured":"Breedveld F C, Lafeber G J M, Doeker G, Claus F, Cats A. Felty's syndrome: autoimmune neutropenia or immunecomplex mediated disease. Rheumatol Int 1985; 5: 253-8.","journal-title":"Rheumatol Int"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724114239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724114239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.49.12.976","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T05:36:08Z","timestamp":1737524168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724114239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,12]]},"references-count":17,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1990,12]]}},"alternative-id":["S0003496724114239"],"URL":"https:\/\/doi.org\/10.1136\/ard.49.12.976","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[1990,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DQw7 and the C4B null allele in rheumatoid arthritis and Felty's syndrome.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.49.12.976","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1990 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}