{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:01:59Z","timestamp":1773054119247,"version":"3.50.1"},"reference-count":61,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[1991,9,1]],"date-time":"1991-09-01T00:00:00Z","timestamp":683683200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1991,9,1]],"date-time":"1991-09-01T00:00:00Z","timestamp":683683200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1991,9]]},"DOI":"10.1136\/ard.50.9.653","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"653-657","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Juvenile chronic arthritis, chronic iridocyclitis, and reactivity to histones."],"prefix":"10.1016","volume":"50","author":[{"given":"A.M","family":"Leak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Woo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"ref_1","first-page":"875","article-title":"Autoimmune rheumatic disorders in childhood-a comparison with adult onset disease","volume":"73","author":"M, Leak A.; A, Isenberg D.","year":"1989","unstructured":"Leak A M, Isenberg D A. Autoimmune rheumatic disorders in childhood-a comparison with adult onset disease. Q 7 Med 1989; 73: 875-993."},{"key":"ref_2","first-page":"545","article-title":"Juvenile chronic arthritis with persistently positive tests for rheumatoid factor","volume":"30","author":"M, Ansell B.","year":"1983","unstructured":"Ansell B M. Juvenile chronic arthritis with persistently positive tests for rheumatoid factor. Ann Pediatr (Paris) 1983; 30: 545-50.","journal-title":"Ann Pediatr (Paris)"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0022-3476(73)80260-4","article-title":"Clinical correlates of antinuclear antibodies in juvenile rheumatoid arthritis","volume":"83","author":"E, Petty R.; T, Cassidy J.; B, Sullivan D.","year":"1973","unstructured":"Petty R E, Cassidy J T, Sullivan D B. Clinical correlates of antinuclear antibodies in juvenile rheumatoid arthritis. J Pediair 1973; 83: 386-9.","journal-title":"J Pediair"},{"key":"ref_4","first-page":"\"1039","article-title":"Antinuclear factors in childhood rheumatic diseases","volume":"69","author":"K, Kornreich H.; E, Drexler; V, Hanson","year":"1966","unstructured":"Kornreich H K, Drexler E, Hanson V. Antinuclear factors in childhood rheumatic diseases. J Pediatr 1966; 69: 1039-45. S Schaller J G, Johnson G D, Holborow E J, et al. The association of antinuclear antibodies with the chronic iridocyclitis of juvenile rheumatoid arthritis (Still's disease). Arthritis Rheum 1974; 17: 409-16.","journal-title":"J Pediatr; The association of antinuclear antibodies with the chronic iridocyclitis of juvenile rheumatoid arthritis (Still's disease"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1001\/archopht.1977.04450100096010","article-title":"Anterior uveitis in juvenile rheumatoid arthritis","volume":"95","author":"J, Kanski J.","year":"1977","unstructured":"Kanski J J. Anterior uveitis in juvenile rheumatoid arthritis. Arch Ophthalmol 1977; 95: 1794-7.","journal-title":"Arch Ophthalmol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/0049-0172(87)90019-9","article-title":"Uveitis associated with juvenile rheumatoid arthritis","volume":"16","author":"M, Rosenberg A.","year":"1987","unstructured":"Rosenberg A M. Uveitis associated with juvenile rheumatoid arthritis. Semin Arthritis Rheun 1987; 16: 158-73.","journal-title":"Semin Arthritis Rheun"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1001\/archopht.1983.01040020087015","article-title":"Early-onset pauciarticular juvenile rheumatoid arthritis. A histopathological study","volume":"101","author":"C, Merriam J.; T, Chylack L.; M, Albert D.","year":"1983","unstructured":"Merriam J C, Chylack L T, Albert D M. Early-onset pauciarticular juvenile rheumatoid arthritis. A histopathological study. Arch Ophthalmol 1983; 101: 1085-92.","journal-title":"Arch Ophthalmol"},{"key":"ref_8","first-page":"217","article-title":"Immunoglobulins and antinuclear antibodies in aqueous humour from patients with juvenile \"rheumatoid\" arthritis (Still's disease)","volume":"97","author":"S, Rahi A.H.; J, Kanski J.; A, Fielder","year":"1977","unstructured":"Rahi A H S, Kanski J J, Fielder A. Immunoglobulins and antinuclear antibodies in aqueous humour from patients with juvenile \"rheumatoid\" arthritis (Still's disease). Trans Ophthalmol Soc UK 1977; 97: 217-22.","journal-title":"Trans Ophthalmol Soc UK"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0889-857X(21)00819-X","article-title":"Current knowledge of the aetiology and pathogenesis ofchronic uveitis accompanying juvenile rheumatoid arthritis","volume":"13","author":"E, Petty R.","year":"1987","unstructured":"Petty R E. Current knowledge of the aetiology and pathogenesis ofchronic uveitis accompanying juvenile rheumatoid arthritis. Rhewn Dis Clin North Am 1987; 13: 19-36.","journal-title":"Rhewn Dis Clin North Am"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/0002-9394(79)90303-9","article-title":"Immune complexes in uveitis","volume":"87","author":"H, Char D.; P, Stein; R, Masi; M, Christensen","year":"1979","unstructured":"Char D H, Stein P, Masi R, Christensen M. Immune complexes in uveitis. AmJ Ophthalmol 1979; 87: 678-81.","journal-title":"AmJ Ophthalmol"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1002\/art.1780200807","article-title":"immune complexes and antinuclear antibodies in juvenile rheumatoid arthritis","volume":"20","author":"D, Rossen R.","year":"1977","unstructured":"Rossen R D, Brewer E J, Person D A, et al. Circulating immune complexes and antinuclear antibodies in juvenile rheumatoid arthritis. Arthritis Rheun 1977; 20: 1485-90.","journal-title":"Arthritis Rheun"},{"key":"ref_12","first-page":"665","article-title":"Clq binding in serum in juvenile rheumatoid arthritis","volume":"7","author":"J, Miller J.; L, Osborne C.; P, Hsu Y.","year":"1980","unstructured":"Miller J J, Osborne C L, Hsu Y P. Clq binding in serum in juvenile rheumatoid arthritis. J Rheumatol 1980; 7:665-70.","journal-title":"J Rheumatol"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1136\/ard.39.2.129","article-title":"Serologic abnormalities in juvenile chronic arthritis: a review of 46 cases","volume":"39","author":"Balogh, Z.; Meretey, K.; Falus, A.; Bozsoky, S.","year":"1980","unstructured":"Balogh Z, Meretey K, Falus A, Bozsoky S. Serologic abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rhewn Dis 1980; 39: 129-34.","journal-title":"Ann Rhewn Dis"},{"key":"ref_14","first-page":"615","article-title":"The significance of antinuclear antibodies in juvenile rheumatoid arthritis associated with chronic bilateral iridocyclitis","volume":"71","author":"M, Egeskjold E.; A, Johansen; H, Permin; M, Hoyeraal H.; T, S0rensen","year":"1982","unstructured":"Egeskjold E M, Johansen A, Permin H, Hoyeraal H M, S0rensen T. The significance of antinuclear antibodies in juvenile rheumatoid arthritis associated with chronic bilateral iridocyclitis. ActaPaediatrScand 1982; 71:615-20.","journal-title":"ActaPaediatrScand"},{"key":"ref_15","first-page":"24","article-title":"Biochemistry of the eye","volume-title":"Clinical ophthalmology","author":"Chader, G.","year":"1987","unstructured":"Chader G. Biochemistry of the eye. In: Miller S, ed. Clinical ophthalmology. Bristol: Wright, 1987: 24-45."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1002\/art.1780271111","article-title":"Use of the HEp2 cell substrate in the detection of antinuclear antibodies in juvenile rheumatoid arthritis","volume":"27","author":"G, Osborn T.; J, Patel N.; L, Moore T.; J, Zuckner","year":"1984","unstructured":"Osborn T G, Patel N J, Moore T L, Zuckner J. Use of the HEp2 cell substrate in the detection of antinuclear antibodies in juvenile rheumatoid arthritis. Arthritis Rheum 1984; 27: 1286-9.","journal-title":"Arthritis Rheum"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1136\/adc.61.2.168","article-title":"Antinuclear antibody studies in juvenile chronic arthritis","volume":"61","author":"M, Leak A.; J, Burman S.; M, Ansell B.","year":"1986","unstructured":"Leak A M, Burman S J, Ansell B M. Antinuclear antibody studies in juvenile chronic arthritis. Arch Dis Child 1986; 61: 168-72.","journal-title":"Arch Dis Child"},{"key":"ref_18","first-page":"358","article-title":"Autoantibody profile in juvenile arthritis","volume":"13","author":"Haynes, D.C.; E, Gershwin M.; L, Robbins D.; J, Miller J.; Cosca, D.","year":"1986","unstructured":"Haynes DC, Gershwin M E, Robbins D L, Miller J J, Cosca D. Autoantibody profile in juvenile arthritis. J Rheunatol 1986; 13: 358-63.","journal-title":"J Rheunatol"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/311532a0","article-title":"Structure of the nucleosome core particle at 7 A resolution","volume":"311","author":"J, Richmond T.; T, Finch J.; B, Rushton; D, Rhodes; A, Klug","year":"1984","unstructured":"Richmond T J, Finch J T, Rushton B, Rhodes D, Klug A. Structure of the nucleosome core particle at 7 A resolution. Nature 1984; 311: 532-7.","journal-title":"Nature"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/S0022-3476(77)80699-9","article-title":"A study of specificities of antinuclear antibodies in juvenile rheumatoid arthritis","volume":"90","author":"A, Alspaugh M.; J, Miller J.","year":"1977","unstructured":"Alspaugh M A, Miller J J. A study of specificities of antinuclear antibodies in juvenile rheumatoid arthritis. J Pediatr 1977; 90: 391-5.","journal-title":"J Pediatr"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1002\/art.1780170613","article-title":"Clinical features and serological abnormalities in juvenile rheumatoid arthritis","volume":"17","author":"D, Rudnicki R.; M, Ruderman; E, Scull","year":"1974","unstructured":"Rudnicki R D, Ruderman M, Scull E, et al. Clinical features and serological abnormalities in juvenile rheumatoid arthritis. Arthritis Rheum 1974; 17: 1007-15.","journal-title":"Arthritis Rheum"},{"key":"ref_22","first-page":"61","article-title":"Antibodies against dsDNA in patients with connective tissue disorders","volume":"203","author":"Permin, H.; Halberg, P.; Christiansen, E.","year":"1978","unstructured":"Permin H, Halberg P, Christiansen E. Antibodies against dsDNA in patients with connective tissue disorders. Acta Med Scand 1978; 203: 61-5.","journal-title":"Acta Med Scand"},{"key":"ref_23","first-page":"416","article-title":"Diagnostic significance of antibody to native DNA in children with juvenile chronic arthritis","volume":"93","author":"CassidyJ, T.; E, Walker S.; J, Soderstrom S.; E, Petty R.; B, Sullivan D.","year":"1978","unstructured":"CassidyJ T, Walker S E, Soderstrom S J, Petty R E, Sullivan D B. Diagnostic significance of antibody to native DNA in children with juvenile chronic arthritis.J7Iediatr 1978; 93: 416-20."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1002\/art.1780180602","article-title":"Antibodies to DNA in patients with rheumatoid arthritis and juvenile rheumatoid arthritis","volume":"18","author":"Bell, C.; Talal, N.; Schur, P.","year":"1975","unstructured":"Bell C, Talal N, Schur P. Antibodies to DNA in patients with rheumatoid arthritis and juvenile rheumatoid arthritis. Arthritis Rheum 1975; 18: 535-40.","journal-title":"Arthritis Rheum"},{"issue":"2","key":"ref_25","first-page":"18","article-title":"Anti-cardiolipin and anti-ssDNA antibodies in ANA positive juvenile arthritis and other rheumatic diseases [abstract]. Clin Exp Rheumatol","volume":"5","author":"M, Leak A.; B, Colaco C.; A, Isenberg D.; C, Dudeney; J, Burman S.; M, Ansell B.","year":"1987","unstructured":"Leak A M, Colaco C B, Isenberg D A, Dudeney C, Burman S J, Ansell B M. Anti-cardiolipin and anti-ssDNA antibodies in ANA positive juvenile arthritis and other rheumatic diseases [abstract]. Clin Exp Rheumatol 1987; 5 (suppl 2): 18."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1136\/ard.47.3.178","article-title":"Autoantibody profile in juvenile chronic arthritis","volume":"47","author":"M, Leak A.","year":"1988","unstructured":"Leak A M. Autoantibody profile in juvenile chronic arthritis [review]. Ann Rheum Dis 1988; 47: 178-82.","journal-title":"Ann Rheum Dis"},{"key":"ref_27","first-page":"362","article-title":"Antinuclear antibodies in Greek juvenile arthritis patients. Clin Exp Rheumatol","volume":"3","author":"D, Siamopoulos-Mavrides A.; K, Mavrides A.","year":"1984","unstructured":"Siamopoulos-Mavrides A D, Mavrides A K. Antinuclear antibodies in Greek juvenile arthritis patients. Clin Exp Rheumatol 1984; 3: 362-3."},{"key":"ref_28","first-page":"512","article-title":"Antinuclear antibody specificity in juvenile chronic arthritis","volume":"33","author":"T, Saulsbury F.","year":"1985","unstructured":"Saulsbury F T. Antinuclear antibody specificity in juvenile chronic arthritis. Clin Res 1985; 33: 512a.","journal-title":"Clin Res"},{"key":"ref_29","first-page":"67","article-title":"Identification of nuclear antigens bound by sera from patients with juvenile rheumatoid arthritis","volume":"29","author":"Brunet, C.; Craft, J.; Nakamura, M.; Pachman, L.; Athreya, B.; Hardin, J.","year":"1986","unstructured":"Brunet C, Craft J, Nakamura M, Pachman L, Athreya B, Hardin J. Identification of nuclear antigens bound by sera from patients with juvenile rheumatoid arthritis [abstract]. Arthnrtis Rheum 1986; 29: S67.","journal-title":"Arthnrtis Rheum"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1002\/j.2326-5205.1989.tb00025.x","article-title":"Reactivity of antinuclear antibodies with histones and other antigens in juvenile rheumatoid arthritis","volume":"32","author":"N, Malleson P.; E, Petty R.; M, Fung; M, Candido E.P.","year":"1989","unstructured":"Malleson P N, Petty R E, Fung M, Candido E P M. Reactivity of antinuclear antibodies with histones and other antigens in juvenile rheumatoid arthritis. Arthritis Rheum 1989; 32: 919-23.","journal-title":"Arthritis Rheum"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1002\/j.2326-5205.1989.tb00019.x","article-title":"Antibodies to histones HI and H5 in sera of patients with juvenile rheumatoid arthritis","volume":"32","author":"D, Pauls J.; E, Silverman; M, Laxer R.; J, Fritzler M.","year":"1989","unstructured":"Pauls J D, Silverman E, Laxer R M, Fritzler M J. Antibodies to histones HI and H5 in sera of patients with juvenile rheumatoid arthritis. Arthritis Rheum 1989; 32: 877-83.","journal-title":"Arthritis Rheum"},{"key":"ref_32","article-title":"Antibodies to HEp2 nuclei in juvenile rheumatoid arthritis (JRA) analysed by immunoblotting","author":"M, Rosenberg A.; A, Prokopchuk P.","unstructured":"Rosenberg A M, Prokopchuk P A. Antibodies to HEp2 nuclei in juvenile rheumatoid arthritis (JRA) analysed by immunoblotting [abstract]. Arthritis Rheum 1989; 32: SI51."},{"key":"ref_33","first-page":"31","article-title":"Etude des anticorps antinucleaires et anti-histones au coms de l'arthrite chronique juvenile","volume":"56","author":"Job-Deslandre, C.; Kapel, N.; J, Weill B.; Maheu, E.; J, Menkes C.","year":"1989","unstructured":"Job-Deslandre C, Kapel N, Weill B J, Maheu E, Menkes C J. Etude des anticorps antinucleaires et anti-histones au coms de l'arthrite chronique juvenile. Rev Rhum Mal Osteoartic 1989; 56: 31-3.","journal-title":"Rev Rhum Mal Osteoartic"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1136\/ard.48.2.114","article-title":"Identification of antihistone antibodies in subsets of juvenile chronic arthritis","volume":"48","author":"Ostensen, M.; Fredriksen, K.; Kass, E.; Rekvig, O.-P.","year":"1989","unstructured":"Ostensen M, Fredriksen K, Kass E, Rekvig O-P. Identification of antihistone antibodies in subsets of juvenile chronic arthritis. Ann Rheun Dis 1989; 48: 114-7.","journal-title":"Ann Rheun Dis"},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1159\/000235131","article-title":"Antibodies from patients with rheumatoid arthritis and juvenile chronic arthritis analysed with core histone synthetic peptides","volume":"91","author":"Tuaillon, N.; Muller, S.; Pasquali, J.-L.","year":"1990","unstructured":"Tuaillon N, Muller S, Pasquali J-L, et al. Antibodies from patients with rheumatoid arthritis and juvenile chronic arthritis analysed with core histone synthetic peptides. It Arch Alergy Appl Immunol 1990; 91: 297-305.","journal-title":"It Arch Alergy Appl Immunol"},{"key":"ref_36","first-page":"104","article-title":"Reactivity to histones and histone peptides in early onset pauciarticular juvenile chronic arthritis","volume":"28","author":"M, Leak A.; S, Muller; N, Tuaillon; P, Woo","year":"1989","unstructured":"Leak A M, Muller S, Tuaillon N, Woo P. Reactivity to histones and histone peptides in early onset pauciarticular juvenile chronic arthritis [abstract]. BrJ Rheumatol 1989; 28: 104.","journal-title":"BrJ Rheumatol"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1126\/science.3983639","article-title":"Crystallographic structure of the octameric histone cores of the nucleosome at a resolution of 3.3A","volume":"228","author":"W, Burlingame R.; E, Love W.; C, Wang B.; R, Hamlin; X, Nguyen H.; N, Moudrianakis E.","year":"1985","unstructured":"Burlingame R W, Love W E, Wang B C, Hamlin R, Nguyen H X, Moudrianakis E N. Crystallographic structure of the octameric histone cores of the nucleosome at a resolution of 3.3A. Science 1985; 228: 546-53.","journal-title":"Science"},{"key":"ref_38","first-page":"271","article-title":"Antihistone antibodies in systemic lupus erythematosus","author":"In, Rubin P.L.","year":"1987","unstructured":"Rubin P L. In: Lahita R G, ed. Antihistone antibodies in systemic lupus erythematosus. USA: Wiley, 1987: 271-89."},{"key":"ref_39","first-page":"139","article-title":"Specificity of antihistone antibodies in systemic rheumatic disease","volume":"1","author":"Muller, S.; V, Van Regenmortel H.M.","year":"1988","unstructured":"Muller S, Van Regenmortel H M V. Specificity of antihistone antibodies in systemic rheumatic disease. International Journal of Immunopathology and Pharmacology 1988; 1: 139-48.","journal-title":"International Journal of Immunopathology and Pharmacology"},{"key":"ref_40","first-page":"3115","article-title":"Antibodies from patients with drug-induced and idiopathic lupus erythematosus react with epitopes restricted to the amino and carboxyl terminus of histone","volume":"135","author":"Gohill, J.; D, Cary P.; Couppez, M.; J, Fritzler M.","year":"1985","unstructured":"Gohill J, Cary P D, Couppez M, Fritzler M J. Antibodies from patients with drug-induced and idiopathic lupus erythematosus react with epitopes restricted to the amino and carboxyl terminus of histone. J Immunol 1985; 135: 3115-21.","journal-title":"J Immunol"},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"446","DOI":"10.4049\/jimmunol.138.2.446","article-title":"Antihistone antibodies in idiopathic and drug-induced lupus recognise distinct intrahistone regions","volume":"138","author":"P, Portanova J.; E, Amdt R.; M, Tan E.; L, Kotzin B.","year":"1987","unstructured":"Portanova J P, Amdt R E, Tan E M, Kotzin B L. Antihistone antibodies in idiopathic and drug-induced lupus recognise distinct intrahistone regions. J Immunol 1987; 138: 446-51.","journal-title":"J Immunol"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"476","DOI":"10.4049\/jimmunol.80.6.476","article-title":"Identification of the nuclear component of the interaction of lupus erythematosus globulin and nuclei","volume":"80","author":"J, Friou G.","year":"1958","unstructured":"Friou G J. Identification of the nuclear component of the interaction of lupus erythematosus globulin and nuclei. J Immunol 1958; 80: 476-81.","journal-title":"J Immunol"},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1111\/j.1365-3083.1976.tb03030.x","article-title":"Studies on antibodies to histones by immunofluorescence","volume":"5","author":"M, Tan E.; J, Robinson; P, Robitaille","year":"1976","unstructured":"Tan E M, Robinson J, Robitaille P. Studies on antibodies to histones by immunofluorescence. Scand J Immunol 1976; 5: 811-8.","journal-title":"Scand J Immunol"},{"key":"ref_44","first-page":"304","article-title":"The clinical application of an ELISA technique for the detection of anti-histone antibodies","volume":"13","author":"Epstein, A.; Greenberg, M.; Halbert, S.; Kramer, L.; Barland, P.","year":"1986","unstructured":"Epstein A, Greenberg M, Halbert S, Kramer L, Barland P. The clinical application of an ELISA technique for the detection of anti-histone antibodies. J Rheumatol 1986; 13: 304-7.","journal-title":"J Rheumatol"},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0090-1229(85)90038-8","article-title":"IgG antibodies to the histone complex H2A-H2B characterise procainamide-induced lupus","volume":"36","author":"L, Rubin R.","year":"1985","unstructured":"Rubin R L, McNally E M, Nusinow S R, Robinson C A, Tan E M. IgG antibodies to the histone complex H2A-H2B characterise procainamide-induced lupus. Clin Immunol Immunopathol 1985; 36: 49-59.","journal-title":"Clin Immunol Immunopathol"},{"key":"ref_46","first-page":"722","article-title":"Anti-histone antibodies detected by ELISA and immunoblotting in systemic lupus erythematosus and rheumatoid arthritis","volume":"13","author":"Costa 0, Monier J-C","year":"1986","unstructured":"Costa 0, Monier J-C. Anti-histone antibodies detected by ELISA and immunoblotting in systemic lupus erythematosus and rheumatoid arthritis. J Rheunatol 1986; 13: 722-5.","journal-title":"J Rheunatol"},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications","volume":"76","author":"Towbin, H.; Staehelin, T.; Gordon, J.","year":"1979","unstructured":"Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350-4.","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref_48","first-page":"49","article-title":"Antinuclear antibodies in the immunotaxonomy of connective tissue disorders","volume":"56","author":"N, Maini R.; J, Charles P.; J, Venables P.","year":"1985","unstructured":"Maini R N, Charles P J, Venables P J. Antinuclear antibodies in the immunotaxonomy of connective tissue disorders. ScandJ Rheumatol [Suppl] 1985; 56: 49-57.","journal-title":"ScandJ Rheumatol [Suppl]"},{"key":"ref_49","first-page":"285","article-title":"Patterns of anti-histone antibody specificity in systemic rheumatic disease","volume":"28","author":"M, Bernstein R.; N, Hobbs R.; S, Lea D.; J, Ward D.; V, Hughes G.R.","year":"1985","unstructured":"Bernstein R M, Hobbs R N, Lea D S, Ward D J, Hughes G R V. Patterns of anti-histone antibody specificity in systemic rheumatic disease. Arthritis Rheum 1985; 28: 285-93.","journal-title":"Arthritis Rheum"},{"key":"ref_50","first-page":"934","article-title":"Profiles of antibodies to histones, DNA and IgG in patients with systemic rheumatic diseases determined by ELISA","volume":"12","author":"Gripenberg, M.; Helve, T.; Kurki, P.","year":"1985","unstructured":"Gripenberg M, Helve T, Kurki P. Profiles of antibodies to histones, DNA and IgG in patients with systemic rheumatic diseases determined by ELISA. J Rheumatol 1985; 12: 934-9.","journal-title":"J Rheumatol"},{"key":"ref_51","first-page":"235","article-title":"Iluorimetric assay tor human antibodies to all the histones. J7 Immunol","volume":"65","author":"N, Hobbs R.; J, Lea D.; J, Ward O.","year":"1983","unstructured":"Hobbs R N, Lea D J, Ward O J. Iluorimetric assay tor human antibodies to all the histones. J7 Immunol Methods 1983; 65: 235-43.","journal-title":"Methods"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1136\/ard.46.5.408","article-title":"Antibodies to the five histones and poly(adenosine diphosphate-ribose) in drug induced lupus: implications for pathogenesis","volume":"46","author":"N, Hobbs R.; A-L, Clayton; M, Bernstein R.","year":"1987","unstructured":"Hobbs R N, Clayton A-L, Bernstein R M. Antibodies to the five histones and poly(adenosine diphosphate-ribose) in drug induced lupus: implications for pathogenesis. Ann Rhewn Dis 1987; 46: 408-16.","journal-title":"Ann Rhewn Dis"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0003-2697(81)90090-7","article-title":"Enzymelinked immunosorbent assay in the study of histone antigens and nucleosome structure","volume":"113","author":"Romac, J.; P, Bouley J.; V, Van Regenmortel M.H.","year":"1981","unstructured":"Romac J, Bouley J P, Van Regenmortel M H V. Enzymelinked immunosorbent assay in the study of histone antigens and nucleosome structure. Anal Biochem 1981; 113: 366-71.","journal-title":"Anal Biochem"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/art.1780230503","article-title":"Characteristics of antinuclear antibodies in rheumatoid arthritis","volume":"23","author":"T, Aitcheson C.; C, Peebles; F, Joslin; M, Tan E.","year":"1980","unstructured":"Aitcheson C T, Peebles C, Joslin F, Tan E M. Characteristics of antinuclear antibodies in rheumatoid arthritis. Arthritis Rheum 1980; 23: 528-38.","journal-title":"Arthritis Rheum"},{"issue":"5","key":"ref_55","first-page":"326","article-title":"Antibodies to histones in rheumatoid arthritis","volume":"1988","author":"Muzellec, Y.; LeGoff, P.; Jouquan, J.; Fauquert, P.; Muller, S.; Youinon, P.","unstructured":"Muzellec Y, LeGoff P, Jouquan J, Fauquert P, Muller S, Youinon P. Antibodies to histones in rheumatoid arthritis. Diagn Clin Immunol 1988-5: 326-31.","journal-title":"Diagn Clin Immunol"},{"key":"ref_56","first-page":"499","article-title":"Uveitis and arthritis induced by adjuvant: clinical, immunologic and histologic characteristics","volume":"16","author":"E, Petty R.; W, Johnston; Q, McCormick A.; W, Hunt D.; J, Rootman; F, Rollins D.","year":"1989","unstructured":"Petty R E, Johnston W, McCormick A Q, Hunt D W, Rootman J, Rollins D F. Uveitis and arthritis induced by adjuvant: clinical, immunologic and histologic characteristics. J Rhewnatol 1989; 16: 499-505.","journal-title":"J Rhewnatol"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0002-9394(80)90108-7","article-title":"Retinal S antigen and uveitis","volume":"89","author":"B, Nussenblatt R.; I, Gery; J, Ballantine E.; B, Wacker W.","year":"1980","unstructured":"Nussenblatt R B, Gery I, Ballantine E J, Wacker W B. Retinal S antigen and uveitis. AmJ Ophthalmol 1980; 89: 173-9.","journal-title":"AmJ Ophthalmol"},{"key":"ref_58","first-page":"1512","article-title":"Molecular mimicry. Yeast histone H3-induced experimental autoimmune uveitis","volume":"142","author":"A, L.; T, Shinohara","year":"1989","unstructured":"Singh V K, Yamaki K, Donoso L A, Shinohara T. Molecular mimicry. Yeast histone H3-induced experimental autoimmune uveitis. J7 Immunol 1989; 142: 1512-7."},{"key":"ref_59","first-page":"426","article-title":"Early-onset pauciarticular juvenile rheumatoid arthritis associated with human leukocyte antigen DRwS, iritis and antinuclear antibody. J7 Clin Invest","volume":"66","author":"Glass, D.; Litvin, D.; Wallace, K.; etal","year":"1980","unstructured":"Glass D, Litvin D, Wallace K, etal. Early-onset pauciarticular juvenile rheumatoid arthritis associated with human leukocyte antigen DRwS, iritis and antinuclear antibody. J7 Clin Invest 1980; 66: 426-9."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1136\/ard.45.6.464","article-title":"Genetic susceptibility to early onset pauciarticular juvenile chronic arthritis: a study of HLA and complement markers in 158 British patients","volume":"45","author":"J, Hall P.; J, Burman S.; R, Laurent M.","year":"1986","unstructured":"Hall P J, Burman S J, Laurent M R, et al. Genetic susceptibility to early onset pauciarticular juvenile chronic arthritis: a study of HLA and complement markers in 158 British patients. Ann Rheum Dis 1986; 45: 464-74.","journal-title":"Ann Rheum Dis"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"9489","DOI":"10.1073\/pnas.86.23.9489","article-title":"A specific HLA-DP[i allele is associated with juvenile rheumatoid arthritis, but not adult rheumatoid arthritis","volume":"86","author":"B, Begovich A.; L, Bugawan T.; S, Nepom B.","year":"1989","unstructured":"Begovich A B, Bugawan T L, Nepom B S, et al. A specific HLA-DP[i allele is associated with juvenile rheumatoid arthritis, but not adult rheumatoid arthritis. Proc Natl Acad Sci USA 1989; 86: 9489-93.","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724106796?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724106796?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.50.9.653","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T05:25:28Z","timestamp":1737523528000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724106796"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,9]]},"references-count":61,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1991,9]]}},"alternative-id":["S0003496724106796"],"URL":"https:\/\/doi.org\/10.1136\/ard.50.9.653","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[1991,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Juvenile chronic arthritis, chronic iridocyclitis, and reactivity to histones.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.50.9.653","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1991 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}