{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T17:25:34Z","timestamp":1770830734409,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[1993,11,1]],"date-time":"1993-11-01T00:00:00Z","timestamp":752112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1993,11,1]],"date-time":"1993-11-01T00:00:00Z","timestamp":752112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1993,11]]},"DOI":"10.1136\/ard.52.11.806","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"806-811","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Vascular cell adhesion molecule 1 and alpha 4 and beta 1 integrins in lymphocyte aggregates in Sj\u00f6gren's syndrome and rheumatoid arthritis."],"prefix":"10.1016","volume":"52","author":[{"given":"J.C.","family":"Edwards","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.S.","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Speight","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.A.","family":"Isenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"ref_1","first-page":"1","article-title":"Lymphocyte and APC traffic. In: Advanced immunology","author":"Male, D.; Champion, B.; Cooke, A.","year":"1987","unstructured":"Male D, Champion B, Cooke A. Lymphocyte and APC traffic. In: Advanced immunology. London: Gower Medical, 1987: 1-8."},{"key":"ref_2","first-page":"999","article-title":"Sj6gren's syndrome","volume-title":"Textbook of rheumatology","author":"Whaley, K.; A, Alspaugh M.","year":"1989","unstructured":"Whaley K, Alspaugh M A. Sj6gren's syndrome. In: Kelley W N, Harris E D, Ruddy S, Sledge C B, eds. Textbook of rheumatology. 3rd ed. Philadelphia: Saunders, 1989: 999-1012.","edition":"3rd ed"},{"key":"ref_3","article-title":"Rheumatoid arthritis: cell and tissue pathology","volume-title":"basis of connective tissue diseases","author":"L, Gardner D.","unstructured":"Gardner D L. Rheumatoid arthritis: cell and tissue pathology. In: Gardner D L, ed. Pathological basis of connective tissue diseases. London: Arnold, 1992: 455."},{"issue":"3","key":"ref_4","first-page":"191","article-title":"naive helper T cells in labial glands from patients with Sjogrens syndrome. Virch Arch A Pathol Anat Histopathol","volume":"419","author":"B, Matthews J.","year":"1991","unstructured":"Matthews J B, Deacon E M, Kitas G D, et al. Primed and naive helper T cells in labial glands from patients with Sjogrens syndrome. Virch Arch A Pathol Anat Histopathol 1991; 419(3): 191-7."},{"key":"ref_5","first-page":"210","article-title":"T cell subpopulations in the labial minor salivary gland histopathologic lesion of Sjogrens syndrome","volume":"18","author":"N, Skopouli F.; C, Fox P.; V, Galanopoulou; C, Atkinson J.; S, Jaffes E.; M, Moutsopoulos H.","year":"1991","unstructured":"Skopouli F N, Fox P C, Galanopoulou V, Atkinson J C, Jaffes E S, Moutsopoulos H M. T cell subpopulations in the labial minor salivary gland histopathologic lesion of Sjogrens syndrome. J Rheumatol 1991; 18: 210-10.","journal-title":"J Rheumatol"},{"key":"ref_6","series-title":"Ann Rheum Dis","first-page":"691","article-title":"cell receptor expression in Sjogren's syndrome","volume":"50","author":"Zumla, A.; Mathur, M.; Stewart, J.; S, Wilkinson L.; Isenberg, D.","year":"1991","unstructured":"Zumla A, Mathur M, Stewart J, Wilkinson L S, Isenberg D. T cell receptor expression in Sjogren's syndrome. Ann Rheum Dis 1991; 50: 691-3."},{"key":"ref_7","first-page":"1504","article-title":"Analysis of T cells bearing different isotypic forms of the gamma\/delta T cell receptor in patients with systemic autoimmune diseases","volume":"18","author":"Gerli, R.; Agea, E.; Bertotto, A.","year":"1991","unstructured":"Gerli R, Agea E, Bertotto A, et al. Analysis of T cells bearing different isotypic forms of the gamma\/delta T cell receptor in patients with systemic autoimmune diseases. JRheumatol 1991; 18: 1504-10.","journal-title":"JRheumatol"},{"key":"ref_8","first-page":"603","article-title":"T cells bearing -y\/8 T cell receptor and their expression of activation antigen in peripheral blood from patients with Sj6grens syndrome. Clin Exp Rheumatol","volume":"9","author":"Ichikawa, Y.; Shimizu, H.; Yoshida, M.; Takaya, M.; Arimori, S.","year":"1991","unstructured":"Ichikawa Y, Shimizu H, Yoshida M, Takaya M, Arimori S. T cells bearing -y\/8 T cell receptor and their expression of activation antigen in peripheral blood from patients with Sj6grens syndrome. Clin Exp Rheumatol 1991; 9: 603-9."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/art.1780310108","article-title":"Increased helper and decreased suppressor inducer phenotypes in the rheumatoid joint","volume":"31","author":"P, Lasky H.; K, Bauer; M, Pope R.","year":"1988","unstructured":"Lasky H P, Bauer K, Pope R M. Increased helper and decreased suppressor inducer phenotypes in the rheumatoid joint. Arthnitis Rheum 1988; 31: 52-9.","journal-title":"Arthnitis Rheum"},{"key":"ref_10","first-page":"11","article-title":"Development of malignant lymphoma in myoepithelial sialadenitis (salivary tissue)","volume":"395","author":"Schmid, U.; Helbron, D.; Lennert, K.","year":"1982","unstructured":"Schmid U, Helbron D, Lennert K. Development of malignant lymphoma in myoepithelial sialadenitis (salivary tissue). PatholAnat 1982; 395: 11-14.","journal-title":"PatholAnat"},{"key":"ref_11","first-page":"657","article-title":"Denman A M. The rheumatoid synovial membrane participates in systemic anti-viral responses. Clin Exp Immunol 1985; 62","author":"K, Pelton B.; R, Harvey A.","unstructured":"Pelton B K, Harvey A R, Denman A M. The rheumatoid synovial membrane participates in systemic anti-viral responses. Clin Exp Immunol 1985; 62: 657-62."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1002\/art.1780280704","article-title":"IgG and IgM rheumatoid factor synthesis in rheumatoid synovial membrane cell cultures","volume":"28","author":"M, Wernick R.; E, Lipsky P.; E, Marban-Arcos; J, Maliakkal J.; D, Edelbaum; M, Ziff","year":"1985","unstructured":"Wernick R M, Lipsky P E, Marban-Arcos E, Maliakkal J J, Edelbaum D, Ziff M. IgG and IgM rheumatoid factor synthesis in rheumatoid synovial membrane cell cultures. Arthritis Rheum 1985; 28: 742-4.","journal-title":"Arthritis Rheum"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(92)90115-S","article-title":"Integrins: versatility modulation, and signalling in cell adhesion","volume":"69","author":"0, Hynes R","year":"1991","unstructured":"Hynes R 0. Integrins: versatility modulation, and signalling in cell adhesion. Cell 1991; 69: 11-25.","journal-title":"Cell"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"4207","DOI":"10.4049\/jimmunol.147.12.4207","article-title":"The VLA-4NCAM-1 pathway is involved in lymphocyte adhesion to endothelium in rheumatoid synovium","volume":"147","author":"M, Van Dinther-Jansen A.C.H.; E, Horst; G, Koopman","year":"1991","unstructured":"Van Dinther-Jansen A C H M, Horst E, Koopman G, et al. The VLA-4NCAM-1 pathway is involved in lymphocyte adhesion to endothelium in rheumatoid synovium. JlImmunol 1991; 147: 4207-10.","journal-title":"JlImmunol"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/0092-8674(89)90775-7","article-title":"Direct expression cloning of vascular cell adhesion molecule-i, a cytokine induced endothelial protein that binds to lymphocytes","volume":"59","author":"Osbom, L.; Hession, C.; Tizard, R.","year":"1989","unstructured":"Osbom L, Hession C, Tizard R, et al. Direct expression cloning of vascular cell adhesion molecule-i, a cytokine induced endothelial protein that binds to lymphocytes. Cell 1989; 59: 1203-5.","journal-title":"Cell"},{"key":"ref_16","first-page":"385","article-title":"Vascular and nonvascular expression of INCAM-1 10. A target for mononuclear leucocyte adhesion molecule in normal and inflamed human tissues","volume":"138","author":"E, Rice G.; M, Munro J.; C, Corless; P, Bevilaqua M.","year":"1991","unstructured":"Rice G E, Munro J M, Corless C, Bevilaqua M P. Vascular and nonvascular expression of INCAM-1 10. A target for mononuclear leucocyte adhesion molecule in normal and inflamed human tissues. AmJfPathol 1991; 138: 385-93.","journal-title":"AmJfPathol"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1002\/eji.1830211132","article-title":"Signalling by vascular cell adhesion molecule-1 (VCAM-1) through VLA-4 promotes CD3 dependent T cell proliferation","volume":"21","author":"Burkly, C.; Jakubowski, A.; M, Newman B.; D, Rosa M.; Chi-Rosso, G.; R, Lobb R.","year":"1991","unstructured":"Burkly C, Jakubowski A, Newman B M, Rosa M D, Chi-Rosso G, Lobb R R. Signalling by vascular cell adhesion molecule-1 (VCAM-1) through VLA-4 promotes CD3 dependent T cell proliferation. Eur J Immunol 1991; 21: 2871-5.","journal-title":"Eur J Immunol"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1126\/science.1697696","article-title":"Adhesion of human B cells to germinal centers in vitro involves VLA-4 and INCAM-I 10","volume":"249","author":"S, Freedman A.; M, Munro J.; E, Rice G.","year":"1990","unstructured":"Freedman A S, Munro J M, Rice G E, et al. Adhesion of human B cells to germinal centers in vitro involves VLA-4 and INCAM-I 10. Science 1990; 249: 1030-3.","journal-title":"Science"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1002\/eji.1830211021","article-title":"Differential expression of VLA-4 integrin by resident and peripheral blood B lymphocytes. Acquisition of functionally active a4, B1 fibronectin receptors upon B cell activation","volume":"21","year":"1991","unstructured":"Postig A, Campanero M R, Garcia-Pardo A, Corbi A L, Sanchez-Madrid F, De Landazuri M 0. Differential expression of VLA-4 integrin by resident and peripheral blood B lymphocytes. Acquisition of functionally active a4,B1 fibronectin receptors upon B cell activation. Eur J Immunol 1991; 21: 2437-45.","journal-title":"Eur J Immunol"},{"key":"ref_20","first-page":"315","article-title":"revised criteria for classification of rheumatoid arthritis","volume":"31","author":"C, Arnett F.; M, Edworthy S.; A, Bloch D.","year":"1987","unstructured":"Arnett F C, Edworthy S M, Bloch D A, et al. The 1987 revised criteria for classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-24.","journal-title":"The"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.4049\/jimmunol.144.7.2558","article-title":"A monoclonal antibody that detects a novel antigen on endothelial cells that is induced by tumour necrosis factor, IL-1 or lipopolysaccharide","volume":"144","author":"M, Wellicome S.; H, Thornhill M.; C, Pitzalis","year":"1990","unstructured":"Wellicome S M, Thornhill M H, Pitzalis C, et al. A monoclonal antibody that detects a novel antigen on endothelial cells that is induced by tumour necrosis factor, IL-1 or lipopolysaccharide. J Immunol 1990; 144: 2558-65.","journal-title":"J Immunol"},{"key":"ref_22","first-page":"322","article-title":"Immunohistological analysis of human mononuclear phagocytes and dendritic cells by using monoclonal antibodies","volume":"54","author":"A, Franklin W.; Y, Mason D.; K, Pulford","year":"1986","unstructured":"Franklin W A, Mason D Y, Pulford K, et al. Immunohistological analysis of human mononuclear phagocytes and dendritic cells by using monoclonal antibodies. Lab Invest 1986; 54: 322-6.","journal-title":"Lab Invest"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/eji.1830110412","article-title":"Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal antibody","volume":"11","author":"L, Beverley P.C.; E, Callard R.","year":"1981","unstructured":"Beverley P C L, Callard R E. Distinctive functional characteristics of human T lymphocytes defined by E rosetting or a monoclonal antibody. EurJ Immunol 1981; 11: 329-34.","journal-title":"EurJ Immunol"},{"key":"ref_24","series-title":"Proceedings of the second international workshop on human leucocyte differentiation antigens","article-title":"B cell leukaemia panel workshop","volume":"38","author":"M, Nadler L.","unstructured":"Nadler L M. B cell leukaemia panel workshop. In: Reinhertz E, ed. Proceedings of the second international workshop on human leucocyte differentiation antigens. Vol. 38. Berlin: Springer, 1985: 43."},{"key":"ref_25","first-page":"1343","article-title":"VLA-3 a novel polypeptide association within the VLA-moleculer complex: cell distribution and biochemical characterisation","volume":"16","year":"1986","unstructured":"Sanchez-Madrid F, De Landazuri M 0, Morago G, Cebrian M, Acevedo A, Bemabeu C. VLA-3 a novel polypeptide association within the VLA-moleculer complex: cell distribution and biochemical characterisation. EurlImmunol 1986; 16: 1343-9.","journal-title":"EurlImmunol"},{"key":"ref_26","volume-title":"4th leucocyte typing workshop","author":"Knapp, P.","year":"1989","unstructured":"Knapp P, ed. 4th leucocyte typing workshop. Oxford: Oxford University Press, 1989: 360, 1018."},{"key":"ref_27","first-page":"232","article-title":"Human B lymphoid differentiation; normal versus malignant","volume":"39","author":"Janossy, J.; Boffill, M.; J, Schuurman H.","year":"1991","unstructured":"Janossy J, Boffill M, Schuurman H J. Human B lymphoid differentiation; normal versus malignant. Netherlands J Med 1991; 39: 232-43.","journal-title":"Netherlands J Med"},{"issue":"1311","key":"ref_28","first-page":"6","article-title":"Newly produced virgin B cells migrate to secondary lymphoid organs but their capacity to enter follicles is restricted","volume":"17","author":"E, Lortan J.; A, Rowbottom C.; S, Oldfield; C, MacLennan I.","year":"1987","unstructured":"Lortan J E, Rowbottom C A, Oldfield S, MacLennan I C. Newly produced virgin B cells migrate to secondary lymphoid organs but their capacity to enter follicles is restricted. EurJImmunol 1987; 17: 1311 -6.","journal-title":"EurJImmunol"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1002\/art.1780261203","article-title":"Changes in vascular endothelium related to lymphocyte collections in diseased synovia","volume":"26","author":"J, Freemont A.; P, Jones C.J.; M, Bromley; P, Andrews","year":"1983","unstructured":"Freemont A J, Jones C J P, Bromley M, Andrews P. Changes in vascular endothelium related to lymphocyte collections in diseased synovia. Arthritis Rheum 1983; 26: 1427-33.","journal-title":"Arthritis Rheum"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724406973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724406973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.52.11.806","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T06:18:52Z","timestamp":1738304332000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724406973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,11]]},"references-count":29,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1993,11]]}},"alternative-id":["S0003496724406973"],"URL":"https:\/\/doi.org\/10.1136\/ard.52.11.806","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[1993,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vascular cell adhesion molecule 1 and alpha 4 and beta 1 integrins in lymphocyte aggregates in Sj\u00f6gren's syndrome and rheumatoid arthritis.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.52.11.806","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1993 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}