{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:17:46Z","timestamp":1790259466992,"version":"4.1.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[1993,9,1]],"date-time":"1993-09-01T00:00:00Z","timestamp":746841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1993,9,1]],"date-time":"1993-09-01T00:00:00Z","timestamp":746841600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1993,9]]},"DOI":"10.1136\/ard.52.9.677","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"677-680","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":89,"title":["Presence of foam cells containing oxidised low density lipoprotein in the synovial membrane from patients with rheumatoid arthritis."],"prefix":"10.1016","volume":"52","author":[{"given":"P.G","family":"Winyard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Tatzber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Esterbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.L","family":"Kus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.R","family":"Blake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.J","family":"Morris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0049-0172(82)90020-8","article-title":"Pathogenesis of rheumatoid arthritis: a vascular hypothesis","volume":"12","author":"M, Rothschild B.; T, Masi A.","year":"1992","unstructured":"Rothschild B M, Masi A T. Pathogenesis of rheumatoid arthritis: a vascular hypothesis. Semin Arthritis Rheum 1992;12:11-31.","journal-title":"Semin Arthritis Rheum"},{"key":"ref_2","first-page":"9","article-title":"Beyond cholesterol: modifications of low density lipoprotein that increase its artherogenicity","volume":"320","author":"Steinberg, D.; Parthasarathy, S.; E, Carew T.; C, Khoo J.; L, Witztum J.","year":"1989","unstructured":"Steinberg D, Parthasarathy S, Carew T E, Khoo J C, Witztum J L. Beyond cholesterol: modifications of low density lipoprotein that increase its artherogenicity. N EnglJ7 Med 1989; 320:9 15-24.","journal-title":"N EnglJ7 Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1146\/annurev.bi.52.070183.001255","article-title":"Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis","volume":"52","author":"S, Brown M.; L, Goldstein J.","year":"1983","unstructured":"Brown M S, Goldstein J L. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Ann Rev Biochem 1983; 52: 223-61.","journal-title":"Ann Rev Biochem"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1172\/JCI115111","article-title":"Gene expression in macrophage-rich human atherosclerotic lesions. 15-Lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts","volume":"87","author":"Yla-Herttuala, S.; E, Rosenfeld M.; Parthasarathy, S.","year":"1991","unstructured":"Yla-Herttuala S, Rosenfeld M E, Parthasarathy S, et al. Gene expression in macrophage-rich human atherosclerotic lesions. 15-Lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts. J Clin Invest 1991;87: 1146-52.","journal-title":"J Clin Invest"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/ard.51.4.481","article-title":"Occurrence of (E)-4-hydroxy-2-nonenal in plasma and synovial fluid of patients with rheumatoid arthritis and osteoarthritis","volume":"51","author":"L, Selley M.; J, Boume D.; R, Bartlett M.","year":"1992","unstructured":"Selley M L, Boume D J, Bartlett M R, et al. Occurrence of (E)-4-hydroxy-2-nonenal in plasma and synovial fluid of patients with rheumatoid arthritis and osteoarthritis. Ann Rheum Dis 1992; 51: 481-4.","journal-title":"Ann Rheum Dis"},{"key":"ref_6","first-page":"395","article-title":"Ironpromoted oxidative damage in rheumatic diseases","volume-title":"human diseases","author":"W, Trenam C.; G, Winyard P.; J, Morris C.; R, Blake D.","year":"1992","unstructured":"Trenam C W, Winyard P G, Morris C J, Blake D R. Ironpromoted oxidative damage in rheumatic diseases. In: Lauffer R B, ed. Iron and human diseases. Boca Raton: CRC Press, 1992: 395-417."},{"key":"ref_7","first-page":"657","article-title":"lipids and lipoproteins in knee-joint synovial fluid and serum from patients with inflammatory joint disease","volume":"83","author":"Fairbum, K.; Grootveld, M.; J, Ward R.","year":"1993","unstructured":"Fairbum K, Grootveld M, Ward R J, et al. ox-Tocopherol, lipids and lipoproteins in knee-joint synovial fluid and serum from patients with inflammatory joint disease. Clin Sci 1993; 83: 657-64.","journal-title":"Clin Sci"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1021\/tx00014a001","article-title":"and functional properties of oxidised low-density lipoprotein","volume":"3","author":"Esterbauer, H.; Dieber-Rotheneder, M.; Waeg, G.; Striegl, G.; Biochemical, Jurgens G.; structural","year":"1990","unstructured":"Esterbauer H, Dieber-Rotheneder M, Waeg G, Striegl G, Jurgens G. Biochemical, structural, and functional properties of oxidised low-density lipoprotein. Chem Res Toxicol 1990; 3: 77-92.","journal-title":"Chem Res Toxicol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1172\/JCI114562","article-title":"Minimally modified low density lipoprotein stimulates monocyte endothelial cell interactions","volume":"85","author":"A, Berliner J.; C, Territo M.; A, Sevanian","year":"1990","unstructured":"Berliner J A, Territo M C, Sevanian A, et al. Minimally modified low density lipoprotein stimulates monocyte endothelial cell interactions. J Clin Invest 1990; 85: 1260-6.","journal-title":"J Clin Invest"},{"key":"ref_10","first-page":"369","article-title":"The pathogenesis of atherosclerosis","volume":"295","author":"Ross, R.; A, Glomset J.","year":"1976","unstructured":"Ross R, Glomset J A. The pathogenesis of atherosclerosis. NEnglJ7Med 1976; 295: 369-77."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1172\/JCI112212","article-title":"Self-perpetuating mechanisms of immunoglobulin G aggregation in rheumatoid inflammation","volume":"76","author":"Lunec, J.; R, Blake D.; J, McCleary S.; Brailsford, S.; A, Bacon P.","year":"1985","unstructured":"Lunec J, Blake D R, McCleary S J, Brailsford S, Bacon P A. Self-perpetuating mechanisms of immunoglobulin G aggregation in rheumatoid inflammation. J Clin Invest 1985; 76: 2084-90.","journal-title":"J Clin Invest"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1161\/01.ATV.10.3.336","article-title":"Distribution of oxidation specific lipidprotein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits","volume":"10","author":"E, Rosenfeld M.; W, Palinski; Y, Henttuala S.; S, Butler; L, Witztum J.","year":"1990","unstructured":"Rosenfeld M E, Palinski W, Henttuala S Y, Butler S, Witztum J L. Distribution of oxidation specific lipidprotein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits. Arteriosclerosis 1990; 10: 336-49.","journal-title":"Arteriosclerosis"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1161\/01.ATV.11.5.1322","article-title":"Effects of copper and histidine on oxidative modification of low density lipoprotein and its subsequent binding to collagen","volume":"11","author":"Kalant, N.; McCormick, S.; A, Parniak M.","year":"1991","unstructured":"Kalant N, McCormick S, Parniak M A. Effects of copper and histidine on oxidative modification of low density lipoprotein and its subsequent binding to collagen. Arteriosclerosis and Thrombosis 1991; 11: 1322-9.","journal-title":"Arteriosclerosis and Thrombosis"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0021-9150(78)90069-2","article-title":"Fibrous longspacing collagen in human atherosclerosis","volume":"31","author":"J, Morris C.; H, Bradby G.V.; W, Walton K.","year":"1978","unstructured":"Morris C J, Bradby G V H, Walton K W. Fibrous longspacing collagen in human atherosclerosis. Atherosclerosis 1978;31: 345-54.","journal-title":"Atherosclerosis"},{"key":"ref_15","article-title":"Development of an in vivo H202-initiated model of joint inflammation: histological and systemic studies","author":"J, Dabbagh A.; R, Blake D.; J, Morris C.","unstructured":"Dabbagh A J, Blake D R, Morris C J. Development of an in vivo H202-initiated model of joint inflammation: histological and systemic studies. Int J Exp Pathol. In press.","journal-title":"Int J Exp"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724032357?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724032357?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.52.9.677","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T08:48:35Z","timestamp":1737449315000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724032357"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,9]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[1993,9]]}},"alternative-id":["S0003496724032357"],"URL":"https:\/\/doi.org\/10.1136\/ard.52.9.677","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[1993,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Presence of foam cells containing oxidised low density lipoprotein in the synovial membrane from patients with rheumatoid arthritis.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.52.9.677","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1993 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}