{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:05:19Z","timestamp":1762160719626,"version":"3.33.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1995,3]]},"DOI":"10.1136\/ard.54.3.225","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T23:49:46Z","timestamp":1217288986000},"page":"225-228","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Antibody to Mycobacterium tuberculosis 65 kDa heat shock protein in patients with rheumatoid arthritis\u2013a survey of antigen-specific antibody isotypes and subclasses in an endemic area of previous tuberculosis infection."],"prefix":"10.1016","volume":"54","author":[{"given":"N.S.","family":"Lai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.","family":"Lan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.L.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.H.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"article-title":"Antigen-specific antibodies of the IgG, IgA, and IgM isotypes and IgG subclasses in serum, SF, or both, were measured by enzyme linked immunosorbent assay (ELISA) using alkaline phosphatase-conjugated mouse anti-human IG1, IgG2, IgG4, IgG, IgA, and IgM antibodies, at 1\/500 dilution. The reaction was stopped after 30 minutes and the amount of bound enzyme assayed; absorbance values were read at 405 nm in an ELISA reader (Metertech, 1960). Absorbance was calculated as the mean of triplicate well readings. In each experiment, 65 kDa antigen-specific monoclonal antibody was used as positive control. The optic density (OD) ratio was calculated as OD of the test samples divided by OD of a standard normal serum used in each plate. The control solution (phosphate buffered saline) never gave a value greater than 0-01. The standard deviations of the triplicate wells were all less than 10%","author":"KDA, H.S.P.","key":"ref_1","unstructured":"KDA HSP Antigen-specific antibodies of the IgG, IgA, and IgM isotypes and IgG subclasses in serum, SF, or both, were measured by enzyme linked immunosorbent assay (ELISA) using alkaline phosphatase-conjugated mouse anti-human IG1, IgG2, IgG4, IgG, IgA, and IgM antibodies, at 1\/500 dilution. The reaction was stopped after 30 minutes and the amount of bound enzyme assayed; absorbance values were read at 405 nm in an ELISA reader (Metertech, 1960). Absorbance was calculated as the mean of triplicate well readings. In each experiment, 65 kDa antigen-specific monoclonal antibody was used as positive control. The optic density (OD) ratio was calculated as OD of the test samples divided by OD of a standard normal serum used in each plate. The control solution (phosphate buffered saline) never gave a value greater than 0-01. The standard deviations of the triplicate wells were all less than 10%."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/1529-0131(195910)2:5<440::AID-ART1780020510>3.0.CO;2-N","article-title":"Studies of polyarthritis and other lesions induced in rats by injection of mycobacteria antigen","volume":"2","author":"M, Pearson C.; D, Wood F.","year":"1964","unstructured":"Pearson C M, Wood F D. Studies of polyarthritis and other lesions induced in rats by injection of mycobacteria antigen. Arthritis Rheum 1964; 2: 440-5.","journal-title":"Arthritis Rheum"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"5117","DOI":"10.1073\/pnas.82.15.5117","article-title":"Arthritis induced by a T lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycan","volume":"82","author":"W, Van Eden; J, Holoshitz; Z, Nevo; A, Frenkel; A, Klajkan; R, Cohen I.","year":"1985","unstructured":"Van Eden W, Holoshitz J, Nevo Z, Frenkel A, Klajkan A, Cohen I R. Arthritis induced by a T lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycan. IProc Natl Acad Sci USA 1985; 82: 5117-20.","journal-title":"IProc Natl Acad Sci USA"},{"key":"ref_4","first-page":"171","article-title":"Cloning of the mycobacterial epitope recognized by T lymphocyte in adjuvant arthritis","volume":"331","author":"W, Van Eden; R, Thole J.E.; R, Van Der Zee","year":"1981","unstructured":"Van Eden W, Thole J E R, Van Der Zee R, et al. Cloning of the mycobacterial epitope recognized by T lymphocyte in adjuvant arthritis. Nature 1981; 331: 171-3.","journal-title":"Nature"},{"key":"ref_5","first-page":"478","article-title":"Synovial fluid T cell reactivity against 65 KD heat shock protein of mycobacterium in early chronic arthritis","volume":"ii:","author":"M, Res P.C.; G, Schaar C.; C, Breedveld F.","year":"1988","unstructured":"Res P C M, Schaar C G, Breedveld F C, et al. Synovial fluid T cell reactivity against 65 KD heat shock protein of mycobacterium in early chronic arthritis. Lancet 1988; ii: 478-80.","journal-title":"Lancet"},{"key":"ref_6","first-page":"211","article-title":"Antibodies level to mycobacteria in relation to HLA type: evidence for nonHLA-linked high levels of antibody to the 65 KD heat shock protein ofM. bovis in rheumatoid arthritis. Clin Exp Immunol","volume":"72","author":"M, Bahr G.; W, Rook G.A.; A, Saffar M.; A, Van Embden J.D.; L, Stanford J.; K, Behbehani","year":"1988","unstructured":"Bahr G M, Rook G A W, Saffar M A, Van Embden J D A, Stanford J L, Behbehani K. Antibodies level to mycobacteria in relation to HLA type: evidence for nonHLA-linked high levels of antibody to the 65 KD heat shock protein ofM. bovis in rheumatoid arthritis. Clin Exp Immunol 1988; 72: 211-15."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1136\/ard.48.2.118","article-title":"Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis","volume":"48","author":"Tsoulfa, G.; W, Rook G.A.; A, Van Embden J.D.","year":"1989","unstructured":"Tsoulfa G, Rook G A W, Van Embden J D A, et al. Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis. Ann Rheum Dis 1989; 48: 118-23.","journal-title":"Ann Rheum Dis"},{"key":"ref_8","first-page":"519","article-title":"Elevated IgG antibody levels to the mycobacterial 65 KD heat shock protein are characteristic of patients with rheumatoid arthritis","volume":"30","author":"Tsoulfa, G.; A, Rook G.; M, Bahr G.","year":"1989","unstructured":"Tsoulfa G, Rook G A, Bahr G M, et al. Elevated IgG antibody levels to the mycobacterial 65 KD heat shock protein are characteristic of patients with rheumatoid arthritis. ScandJl1mmunol 1989; 30: 519-27."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/rheumatology\/31.9.615","article-title":"Detection of mycobacterium tuberculosis antigen in synovial fluid of patients with rheumatoid arthritis","volume":"31","author":"L, Lan J.; H, Wu C.","year":"1992","unstructured":"Lan J L, Wu C H. Detection of mycobacterium tuberculosis antigen in synovial fluid of patients with rheumatoid arthritis. BrJ Rheum 1992; 31: 615-8.","journal-title":"BrJ Rheum"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1002\/art.1780340909","article-title":"Autoantibodies to human stress proteins","volume":"34","author":"N, Jarjour W.; D, Jeffiies B.; S, Davis J.; J, Welch W.; T, Mimura; B, Winfield J.","year":"1991","unstructured":"Jarjour W N, Jeffiies B D, Davis J S, Welch W J, Mimura T, Winfield J B. Autoantibodies to human stress proteins. Arthritis Rheum 1991; 34: 1133-38.","journal-title":"Arthritis Rheum"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/0896-8411(91)90051-D","article-title":"Reaction of antibody to mycobacterial 65 KD heat shock protein with human chondrocytes","volume":"4","author":"Kimura, L.; Plymyer, M.; Mclean, L.; Yamaga, K.; Lance, E.","year":"1991","unstructured":"Kimura L, Plymyer M, Mclean L, Yamaga K, Lance E. Reaction of antibody to mycobacterial 65 KD heat shock protein with human chondrocytes. J Autoimmun 1991; 4: 881-92.","journal-title":"J Autoimmun"},{"key":"ref_12","first-page":"1013","article-title":"Antibodies to the mycobacterial 65 KD heat shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis","volume":"137","author":"R, Graeff-Meeder E.; M, Voorhorst; W, Van Eden","year":"1990","unstructured":"Graeff-Meeder E R, Voorhorst M, Van Eden W, et al. Antibodies to the mycobacterial 65 KD heat shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis. Am J Pathol 1990; 137: 1013-7.","journal-title":"Am J Pathol"},{"issue":"1371","key":"ref_13","first-page":"80","article-title":"Antigenic specificity of rheumatoid synovial fluid lymphocytes","volume":"32","author":"M, Pope R.; A, Pahlavani M.; E, LaCour; S, Sambol; V, Desai B.","year":"1989","unstructured":"Pope R M, Pahlavani M A, LaCour E, Sambol S, Desai B V. Antigenic specificity of rheumatoid synovial fluid lymphocytes. Arthritis Rheum 1989; 32: 1371 -80.","journal-title":"Arthritis Rheum"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0049-0172(91)90010-W","article-title":"Lymphocyte migration in healthy and inflammatory rheumatic disease","volume":"20","author":"Manolios, N.; Geczy, C.; Schrieber, L.","year":"1991","unstructured":"Manolios N, Geczy C, Schrieber L. Lymphocyte migration in healthy and inflammatory rheumatic disease. Seminar Arthritis Rheum 1991; 20: 339-52.","journal-title":"Seminar Arthritis Rheum"},{"key":"ref_15","first-page":"357","article-title":"Selective IgG subclass deficiency: quantification and clinical relevance. Clin Exp Immunol","volume":"81","author":"Jefferis, R.; S, Kumararatne D.","year":"1990","unstructured":"Jefferis R, Kumararatne D S. Selective IgG subclass deficiency: quantification and clinical relevance. Clin Exp Immunol 1990; 81: 357-67."},{"key":"ref_16","first-page":"297","article-title":"Analysis of immune complexes in synovial effusions of patients with rheumatoid arthritis. Clin Exp Immunol","volume":"39","author":"Male, D.; M, Roitt I.; C, Hay F.","year":"1980","unstructured":"Male D, Roitt I M, Hay F C. Analysis of immune complexes in synovial effusions of patients with rheumatoid arthritis. Clin Exp Immunol 1980; 39: 297-332."}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724403312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724403312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.54.3.225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T11:32:54Z","timestamp":1737545574000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724403312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,3]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,3]]}},"alternative-id":["S0003496724403312"],"URL":"https:\/\/doi.org\/10.1136\/ard.54.3.225","relation":{},"ISSN":["0003-4967"],"issn-type":[{"type":"print","value":"0003-4967"}],"subject":[],"published":{"date-parts":[[1995,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antibody to Mycobacterium tuberculosis 65 kDa heat shock protein in patients with rheumatoid arthritis\u2013a survey of antigen-specific antibody isotypes and subclasses in an endemic area of previous tuberculosis infection.","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.54.3.225","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1995 \u00a9 THE AUTHORS. Published by Elsevier B.V. on behalf of European Alliance of Associations for Rheumatology, EULAR. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}