{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T23:23:46Z","timestamp":1745018626051,"version":"3.33.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[1999,12]]},"DOI":"10.1136\/ard.58.12.757","type":"journal-article","created":{"date-parts":[[2008,12,6]],"date-time":"2008-12-06T00:32:33Z","timestamp":1228523553000},"page":"757-761","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Increased IgA rheumatoid factor and VH1 associated cross reactive idiotype expression in patients with Lyme arthritis and neuroborreliosis"],"prefix":"10.1016","volume":"58","author":[{"given":"John S","family":"Axford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David H E","family":"Rees","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rizgar A","family":"Mageed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Wordsworth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azita","family":"Alavi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen C","family":"Steere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1136\/ard.58.12.757_bib1","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1136\/ard.53.9.553","article-title":"Lyme arthritis","volume":"53","author":"Rees","year":"1994","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.58.12.757_bib2","doi-asserted-by":"crossref","first-page":"725","DOI":"10.7326\/0003-4819-107-5-725","article-title":"The clinical evolution of Lyme arthritis","volume":"107","author":"Steere","year":"1987","journal-title":"Ann Intern Med"},{"key":"10.1136\/ard.58.12.757_bib3","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1056\/NEJM199401273300401","article-title":"Detection of Borrelia burgdorferi DNA by the polymerase chain reaction in synovial fluid from patients with Lyme arthritis","volume":"330","author":"Nocton","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1136\/ard.58.12.757_bib4","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1002\/art.1780370616","article-title":"Treatment of Lyme arthritis","volume":"37","author":"Steere","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.58.12.757_bib5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1056\/NEJM199007263230402","article-title":"Association of chronic Lyme arthritis with HLA-DR4 and HLA-DR2 alleles [published erratum appears in N Engl J Med 1991;324:129] [see comments]","volume":"323","author":"Steere","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1136\/ard.58.12.757_bib6","doi-asserted-by":"crossref","first-page":"2774","DOI":"10.1128\/iai.61.7.2774-2779.1993","article-title":"Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi","volume":"61","author":"Kalish","year":"1993","journal-title":"Infect Immun"},{"key":"10.1136\/ard.58.12.757_bib7","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1084\/jem.180.6.2069","article-title":"The T helper response in Lyme arthritis: differential recognition of Borrelia burgdorferi outer surface protein A (OspA) in patients with treatment-resistant or treatment-responsive Lyme arthritis","volume":"180","author":"Lengl-JanBen","year":"1994","journal-title":"J Exp Med"},{"key":"10.1136\/ard.58.12.757_bib8","doi-asserted-by":"crossref","first-page":"10049","DOI":"10.1073\/pnas.86.24.10049","article-title":"HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region","volume":"86","author":"Wordsworth","year":"1989","journal-title":"Proct Natl Acad Sci"},{"key":"10.1136\/ard.58.12.757_bib9","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1136\/ard.52.3.199","article-title":"Expression of public idiotypes in patients with Lyme arthritis","volume":"52","author":"Axford","year":"1993","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.58.12.757_bib10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0896-8411(89)90106-6","article-title":"Autoreactive T cells in rheumatic disease (1). Analysis of growth frequencies and autoreactivity of T cells in patients with rheumatoid arthritis and Lyme disease","volume":"2","author":"Schlesier","year":"1989","journal-title":"J Autoimmun"},{"key":"10.1136\/ard.58.12.757_bib11","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1002\/art.1780310818","article-title":"Anticardiolipin antibodies in Lyme disease","volume":"31","author":"Mackworth-Young","year":"1988","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.58.12.757_bib12","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1093\/infdis\/167.6.1372","article-title":"Cross-reactivity between Borrelia burgdorferi flagellin and a human axonal 64,000 molecular weight protein","volume":"167","author":"Sigal","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1136\/ard.58.12.757_bib13","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1136\/ard.52.2.161","article-title":"Is measurement of rheumatoid factor isotypes clinically useful?","volume":"52","author":"Jonsson","year":"1993","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.58.12.757_bib14","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/art.1780220907","article-title":"IgG rheumatoid factor","volume":"22","author":"Pope","year":"1979","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.58.12.757_bib15","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1136\/ard.51.7.863","article-title":"Population study of the importance of rheumatoid factor isotypes in adults","volume":"51","author":"Jonsson","year":"1992","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.58.12.757_bib16","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0022-1759(84)90061-9","article-title":"Use of monoclonal antibodies and F(ab\u2018)2 enzyme conjugates in ELISA for IgM, IgA and IgG rheumatoid factors","volume":"71","author":"Tietsson","year":"1984","journal-title":"J Immunol Methods"},{"key":"10.1136\/ard.58.12.757_bib17","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1136\/ard.51.9.1029","article-title":"Clinical significance of rheumatoid factors in early rheumatoid arthritis: results of a follow up study","volume":"51","author":"van Zeben","year":"1992","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.58.12.757_bib18","first-page":"772","article-title":"IgM rheumatoid factor in Lyme disease: correlation with disease activity, total serum IgM and IgM specific antibody to Borrelia burgdorferi","volume":"14","author":"Kajula","year":"1987","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.58.12.757_bib19","doi-asserted-by":"crossref","first-page":"314","DOI":"10.3109\/03009748809096784","article-title":"Acquired transient autoimmune reactions in Lyme arthritis: correlation between rheumatoid factor and disease activity","volume":"75","author":"Goebel","year":"1988","journal-title":"Scand J Rheumatol Suppl"},{"key":"10.1136\/ard.58.12.757_bib20","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","article-title":"The American Rheumatology Association 1987 revised diagnostic criteria for the classification of RA","volume":"31","author":"Arnett","year":"1988","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.58.12.757_bib21","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1146\/annurev.iy.01.040183.003033","article-title":"Genetics, expression and function of idiotypes","volume":"1","author":"Rajewski","year":"1983","journal-title":"Ann Rev Immunol"},{"key":"10.1136\/ard.58.12.757_bib22","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1084\/jem.174.1.109","article-title":"Selective expression of a VHIV subfamily of immunoglobulin genes in human CD5+ B lymphocytes from cord blood","volume":"174","author":"Mageed","year":"1991","journal-title":"J Exp Med"},{"key":"10.1136\/ard.58.12.757_bib23","first-page":"1","article-title":"Hypervariable regions, idiotypy and the antibody combining site","volume":"30","author":"Capra","year":"1975","journal-title":"Adv Immunol"},{"key":"10.1136\/ard.58.12.757_bib24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/infdis\/167.2.392","article-title":"Western blotting in the serodiagnosis of Lyme disease","volume":"167","author":"Dressler","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1136\/ard.58.12.757_bib25","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/BF00541285","article-title":"Immunogenic and antigenic epitopes and immunoglobulins. XVII. Monoclonal anti-idiotopes reactive with common and restricted idiotopes to the heavy chain of human rheumatoid factor","volume":"6","author":"Mageed","year":"1986","journal-title":"Rheumatol Int"},{"key":"10.1136\/ard.58.12.757_bib26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF02274784","article-title":"A highly conserved conformational idiotope on human IgM rheumatoid factor paraproteins of the Wa cross-reactive idiotype family defined by a monoclonal antibody","volume":"10","author":"Mageed","year":"1990","journal-title":"Rheumatol Int"},{"key":"10.1136\/ard.58.12.757_bib27","doi-asserted-by":"crossref","first-page":"936","DOI":"10.4049\/jimmunol.146.3.936","article-title":"Expression of VHIII-associated cross-reactive idiotypes on human B lymphocytes. Association with staphylococcal protein A binding and Staphylococcus aureus Cowan I stimulation","volume":"146","author":"Shokri","year":"1991","journal-title":"J Immunol"},{"key":"10.1136\/ard.58.12.757_bib29","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1093\/infdis\/167.3.665","article-title":"Non-protein antigens of Borrelia burgdorferi","volume":"167","author":"Wheeler","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1136\/ard.58.12.757_bib28","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1093\/rheumatology\/32.10.862","article-title":"A quantitative ELISA for the measurement of rheumatoid factor associated cross-reactive idiotypes in serum from patients with rheumatic diseases","volume":"32","author":"Shokri","year":"1993","journal-title":"Br J Rheumatol"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724435310?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724435310?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.58.12.757","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T05:26:48Z","timestamp":1737264408000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724435310"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12]]},"references-count":29,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["S0003496724435310"],"URL":"https:\/\/doi.org\/10.1136\/ard.58.12.757","relation":{},"ISSN":["0003-4967"],"issn-type":[{"type":"print","value":"0003-4967"}],"subject":[],"published":{"date-parts":[[1999,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased IgA rheumatoid factor and VH1 associated cross reactive idiotype expression in patients with Lyme arthritis and neuroborreliosis","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.58.12.757","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1999 Annals of the Rheumatic Diseases, Published by Elsevier Inc. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}