{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T03:54:52Z","timestamp":1777694092407,"version":"3.51.4"},"reference-count":32,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,11,1]],"date-time":"2000-11-01T00:00:00Z","timestamp":973036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[2000,11]]},"DOI":"10.1136\/ard.59.11.898","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T10:45:32Z","timestamp":1027766732000},"page":"898-903","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Characterisation of autoantibodies to neutrophil granule constituents among patients with reactive arthritis, rheumatoid arthritis, and ulcerative colitis"],"prefix":"10.1016","volume":"59","author":[{"given":"Henning","family":"Locht","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Skogh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan","family":"Wiik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1136\/ard.59.11.898_bib1","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0049-0172(95)80027-1","article-title":"Antineutrophil cytoplasmic antibodies: major autoantigens, pathophysiology and disease association.","volume":"25","author":"Schultz","year":"1995","journal-title":"Semin Arthritis Rheum"},{"key":"10.1136\/ard.59.11.898_bib2","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1093\/ndt\/14.6.1366","article-title":"Pathophysiology of ANCA-associated glomerulonephritis.","volume":"14","author":"Muller Kobold","year":"1999","journal-title":"Nephrol Dial Transplant"},{"key":"10.1136\/ard.59.11.898_bib3","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1006\/jaut.1993.1015","article-title":"Classic anti-neutrophil cytoplasmic autoantibodies (cANCA), \u201cWegener\u00e2\u20ac\u2122s autoantigen and their immunopathogenetic role in Wegener\u00e2\u20ac\u2122s granulomatosis.","volume":"3","author":"Gross","year":"1993","journal-title":"J Autoimmun"},{"key":"10.1136\/ard.59.11.898_bib4","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1365-3083.1991.tb01530.x","article-title":"Anti-granulocyte antibodies (C-ANCA, P-ANCA, GS-ANA) studied by confocal scanning laser fluorescence microscopy, ELISA and chemiluminescence techniques.","volume":"34","author":"Skogh","year":"1991","journal-title":"Scand J Immunol"},{"key":"10.1136\/ard.59.11.898_bib5","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1002\/art.1780351210","article-title":"Anti-lactoferrin antibodies in patients with rheumatoid arthritis are associated with vasculitis.","volume":"35","author":"Coremans","year":"1992","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.59.11.898_bib6","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1002\/art.1780380509","article-title":"Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus.","volume":"38","author":"Schnabel","year":"1995","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.59.11.898_bib7","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/gut.34.1.56","article-title":"Antilactoferrin antibodies and other types of ANCA in ulcerative colitis, primary sclerosing cholangitis and Crohn\u00e2\u20ac\u2122s disease.","volume":"34","author":"Peen","year":"1993","journal-title":"Gut"},{"key":"10.1136\/ard.59.11.898_bib8","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1365-2249.1992.tb05835.x","article-title":"Antineutrophil cytoplasmic antibodies (ANCA) directed against cathepsin G in ulcerative colitis, Crohn\u00e2\u20ac\u2122s disease and primary sclerosing cholangitis.","volume":"90","author":"Halbwachs-Mecarelli","year":"1992","journal-title":"Clin Exp Immunol"},{"key":"10.1136\/ard.59.11.898_bib9","series-title":"ANCA associated vasculitidis.","first-page":"267","article-title":"Autoantibodies directed against lysozyme: a new target antigen for antineutrophil cytoplasmic antibodies (ANCA).","author":"Schmitt","year":"1993"},{"key":"10.1136\/ard.59.11.898_bib10","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1046\/j.1365-2249.1996.d01-654.x","article-title":"Anti-neutrophil cytoplasmic antibodies (ANCA) directed against bactericidal\/permeability increasing protein (BPI): a new seromarker for inflammatory bowel disease and associated disorders.","volume":"104","author":"Stoffel","year":"1996","journal-title":"Clin Exp Immunol"},{"key":"10.1136\/ard.59.11.898_bib11","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1136\/gut.40.1.105","article-title":"Antineutrophil cytoplasm autoantibodies against bactericidal\/permeability increasing protein in inflammatory bowel disease.","volume":"40","author":"Walmsley","year":"1997","journal-title":"Gut"},{"key":"10.1136\/ard.59.11.898_bib12","first-page":"2304","article-title":"Antineutrophil cytoplasmic antibodies in reactive arthritis.","volume":"22","author":"Locht","year":"1995","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.59.11.898_bib13","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1006\/abio.1997.2374","article-title":"Purification of Wegener\u00e2\u20ac\u2122s granulomatosis autoantigen, proteinase 3, from neutrophils by Triton X-114 extraction of azurophilic granules.","volume":"253","author":"Heegaard","year":"1997","journal-title":"Anal Biochem"},{"key":"10.1136\/ard.59.11.898_bib14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0022-1759(97)00082-3","article-title":"A simple high yield procedure for purification of human proteinase 3, the main molecular target of cANCA.","volume":"206","author":"Stummann","year":"1997","journal-title":"J Immunol Methods"},{"key":"10.1136\/ard.59.11.898_bib15","first-page":"219","article-title":"Letter to the editor.","volume":"222","author":"Audrain","year":"1999","journal-title":"J Immunol Methods"},{"key":"10.1136\/ard.59.11.898_bib16","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1083\/jcb.97.1.52","article-title":"Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.","volume":"97","author":"Borregaard","year":"1983","journal-title":"J Cell Biol"},{"key":"10.1136\/ard.59.11.898_bib17","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1002\/1529-0131(199809)41:9<1521::AID-ART2>3.0.CO;2-A","article-title":"Antineutrophil cytoplasmic antibodies.","volume":"41","author":"Hoffman","year":"1998","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.59.11.898_bib18","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1046\/j.1523-1755.1998.00807.x","article-title":"Diagnostic value of standardized assays for anti-neutrophil cytoplasmic antibodies in ideopathic systemic vasculitis.","volume":"53","author":"Hagen","year":"1998","journal-title":"Kidney Int"},{"key":"10.1136\/ard.59.11.898_bib19","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1111\/j.1365-2249.1997.tb08324.x","article-title":"Specificities of anti-neutrophil autoantibodies in patients with rheumatoid arthritis (RA).","volume":"110","author":"Brimnes","year":"1997","journal-title":"Clin Exp Immunol"},{"key":"10.1136\/ard.59.11.898_bib20","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1023\/A:1026683224057","article-title":"Autoantibodies to molecular targets in neutrophils in patients with ulcerative colitis.","volume":"44","author":"Brimnes","year":"1999","journal-title":"Dig Dis Sci"},{"key":"10.1136\/ard.59.11.898_bib21","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1136\/jcp.47.3.257","article-title":"Neutrophil cytoplasmic antibodies (pANCA) in ulcerative colitis.","volume":"47","author":"Ellerbroek","year":"1994","journal-title":"J Clin Pathol"},{"key":"10.1136\/ard.59.11.898_bib22","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1006\/jaut.1996.0114","article-title":"Relationship between ANCA and clinical activity in inflammatory bowel diseases: variation in prevalence of ANCA and evidence of heterogeneity.","volume":"10","author":"Abad","year":"1997","journal-title":"J Autoimmun"},{"key":"10.1136\/ard.59.11.898_bib23","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/BF02088340","article-title":"Anti-neutrophil cytoplasmic antibodies (ANCA) in sera from patients with inflammatory bowel diseases (IBD).","volume":"39","author":"Broekroelofs","year":"1994","journal-title":"Dig Dis Sci"},{"key":"10.1136\/ard.59.11.898_bib24","first-page":"783","article-title":"Antigen specificity of circulating anti-neutrophil cytoplasmic antibodies in inflammatory bowel disease.","volume":"7","author":"Kossa","year":"1995","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1136\/ard.59.11.898_bib25","first-page":"2273","article-title":"The evolution of spondylarthropathies in relation to gut histology. II. Histological aspects.","volume":"22","author":"Mielants","year":"1995","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.59.11.898_bib26","doi-asserted-by":"crossref","first-page":"667","DOI":"10.3168\/jds.S0022-0302(97)75985-X","article-title":"Antibacterial peptides of bovine lactoferrin: purification and characterization.","volume":"80","author":"Dionysius","year":"1997","journal-title":"J Dairy Sci"},{"key":"10.1136\/ard.59.11.898_bib27","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1006\/cimm.1997.1246","article-title":"Bovine lactoferrin stimulates the phagocytic activity of human neutrophils: identification of its active domain.","volume":"187","author":"Miyachi","year":"1998","journal-title":"Cell Immunol"},{"key":"10.1136\/ard.59.11.898_bib28","doi-asserted-by":"crossref","first-page":"662","DOI":"10.4049\/jimmunol.144.2.662","article-title":"Bactericidal\/permeability increasing protein has endotoxin-neutralizing activity.","volume":"144","author":"Marra","year":"1990","journal-title":"J Immunol"},{"key":"10.1136\/ard.59.11.898_bib29","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/978-1-4615-2548-6_8","article-title":"The effect of lactoferrin on gram negative bacteria.","volume":"357","author":"Ellison","year":"1994","journal-title":"Adv Exp Med Biol"},{"key":"10.1136\/ard.59.11.898_bib30","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/978-1-4615-2548-6_14","article-title":"The role of lactoferrin as an anti-inflammatory molecule.","volume":"357","author":"Britigan","year":"1994","journal-title":"Adv Exp Med Biol"},{"key":"10.1136\/ard.59.11.898_bib31","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1042\/bj2640447","article-title":"Neutrophil degranulation inhibits potential hydroxyl-radical formation.","volume":"264","author":"Britigan","year":"1989","journal-title":"Biochem J"},{"key":"10.1136\/ard.59.11.898_bib32","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1056\/NEJM198901263200404","article-title":"Yersinia antigens in synovial fluid cells from patiens with reactive arthritis.","volume":"320","author":"Granfors","year":"1989","journal-title":"N Engl J Med"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724424680?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724424680?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.59.11.898","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T05:15:44Z","timestamp":1737263744000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724424680"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,11]]},"references-count":32,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2000,11]]}},"alternative-id":["S0003496724424680"],"URL":"https:\/\/doi.org\/10.1136\/ard.59.11.898","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[2000,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterisation of autoantibodies to neutrophil granule constituents among patients with reactive arthritis, rheumatoid arthritis, and ulcerative colitis","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.59.11.898","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Copyright 2000 by Annals of the Rheumatic Diseases, Published by Elsevier Inc. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}