{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T10:25:25Z","timestamp":1791973525474,"version":"4.4.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2002,12,1]],"date-time":"2002-12-01T00:00:00Z","timestamp":1038700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2002,12,1]],"date-time":"2002-12-01T00:00:00Z","timestamp":1038700800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ard.eular.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of the Rheumatic Diseases"],"published-print":{"date-parts":[[2002,12]]},"DOI":"10.1136\/ard.61.12.1065","type":"journal-article","created":{"date-parts":[[2002,11,12]],"date-time":"2002-11-12T20:42:43Z","timestamp":1037133763000},"page":"1065-1070","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":171,"title":["Definition of risk factors for death, end stage renal disease, and thromboembolic events in a monocentric cohort of 338 patients with systemic lupus erythematosus"],"prefix":"10.1016","volume":"61","author":[{"given":"K","family":"Manger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B","family":"Manger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Repp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Geisselbrecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Geiger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Pfahlberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Harrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J R","family":"Kalden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1136\/ard.61.12.1065_bib1","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1172\/JCI116000","article-title":"Major histocompatibility complex haplotypes and complement C4 alleles in systemic lupus erythematosus. Results of a multicenter study","volume":"90","author":"Hartung","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1136\/ard.61.12.1065_bib2","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1002\/1529-0131(199807)41:7<1181::AID-ART6>3.0.CO;2-C","article-title":"Fcgamma receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: association with clinical symptoms","volume":"41","author":"Manger","year":"1998","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.61.12.1065_bib3","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1749-6632.1997.tb52070.x","article-title":"Clinical relevance of Fc gamma receptor polymorphisms","volume":"815","author":"Rascu","year":"1997","journal-title":"Ann NY Acad Sci"},{"key":"10.1136\/ard.61.12.1065_bib4","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/00002281-199809000-00002","article-title":"The genetics of lupus","volume":"10","author":"Tan","year":"1998","journal-title":"Curr Opin Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib5","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/S0952-7915(98)80090-3","article-title":"The genetics of human systemic lupus erythematosus","volume":"10","author":"Harley","year":"1998","journal-title":"Curr Opin Immunol"},{"key":"10.1136\/ard.61.12.1065_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1097\/00002281-200003000-00001","article-title":"Update on genetic risk factors for systemic lupus erythematosus and rheumatoid arthritis","volume":"12","author":"Criswell","year":"2000","journal-title":"Curr Opin Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/art.1780390303","article-title":"The development and initial validation of the Systemic Lupus International Collaborating Clinics\/American College of Rheumatology damage index for systemic lupus erythematosus [see comments]","volume":"39","author":"Gladman","year":"1996","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.61.12.1065_bib8","first-page":"541","volume":"10","author":"Vitali","year":"1992","journal-title":"Clin Exp Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib9","first-page":"549","volume":"10","author":"Bencivelli","year":"1992","journal-title":"Clin Exp Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib10","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1002\/art.1780251101","article-title":"The 1982 revised criteria for the classification of systemic lupus erythematosus","volume":"25","author":"Tan","year":"1982","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.61.12.1065_bib11","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1002\/art.1780400928","article-title":"Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [letter] [see comments]","volume":"40","author":"Hochberg","year":"1997","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.61.12.1065_bib12","series-title":"Harrison's principles of internal medicine","first-page":"1876","article-title":"Systemic lupus erythematosus","volume":"2","author":"Hahn","year":"1998"},{"key":"10.1136\/ard.61.12.1065_bib13","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"53","author":"Kaplan EL","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1136\/ard.61.12.1065_bib14","series-title":"Survival analysis: A self learning text","volume":"1","author":"Kleinbaum","year":"1986"},{"key":"10.1136\/ard.61.12.1065_bib15","series-title":"Analysis of survival data","author":"Cox Dr","year":"1984"},{"key":"10.1136\/ard.61.12.1065_bib16","series-title":"Medical uses of statistics","author":"Bailar","year":"1986"},{"key":"10.1136\/ard.61.12.1065_bib17","first-page":"1061","article-title":"Mortality studies in systemic lupus erythematosus. Results from a single center. III. Improved survival over 24 years","volume":"24","author":"Urowitz","year":"1997","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib18","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/00002281-199509000-00007","article-title":"Prognosis and treatment of systemic lupus erythematosus","volume":"7","author":"Gladman","year":"1995","journal-title":"Curr Opin Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib19","first-page":"1259","article-title":"Mortality studies in systemic lupus erythematosus. Results from a single center. I. Causes of death","volume":"22","author":"Abu-Shakra","year":"1995","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib20","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3109\/03009749109165284","article-title":"Outcome of systemic lupus erythematosus. A study of 66 patients over 7 years with special reference to the predictive value of anti-DNA antibody determinations","volume":"20","author":"Gripenberg","year":"1991","journal-title":"Scand J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0049-0172(91)90040-7","article-title":"Variables associated with decreased survival in systemic lupus erythematosus","volume":"21","author":"Seleznick","year":"1991","journal-title":"Semin Arthritis Rheum"},{"key":"10.1136\/ard.61.12.1065_bib22","first-page":"685","article-title":"Incidence studies of systemic lupus erythematosus in southern Sweden: increasing age, decreasing frequency of renal manifestations and good prognosis","volume":"27","author":"Stahl-Hallengren","year":"2000","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib23","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1080\/030097499442522","article-title":"Mortality and causes of death of 513 Danish patients with systemic lupus erythematosus","volume":"28","author":"Jacobsen","year":"1999","journal-title":"Scand J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib24","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0002-9343(76)90431-9","article-title":"The bimodal mortality pattern of systemic lupus erythematosus","volume":"60","author":"Urowitz","year":"1976","journal-title":"Am J Med"},{"key":"10.1136\/ard.61.12.1065_bib25","first-page":"171","article-title":"Systemic lupus erythematosus survival in Hungary. Results from a single centre","volume":"17","author":"Kiss","year":"1999","journal-title":"Clin Exp Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib26","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/rheumatology\/39.3.238","article-title":"How to improve morbidity and mortality in systemic lupus erythematosus","volume":"39","author":"Urowitz","year":"2000","journal-title":"Rheumatology (Oxford)"},{"key":"10.1136\/ard.61.12.1065_bib27","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1093\/oxfordjournals.aje.a009122","article-title":"Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study","volume":"145","author":"Manzi","year":"1997","journal-title":"Am J Epidemiol"},{"key":"10.1136\/ard.61.12.1065_bib28","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/rheumatology\/39.4.399","article-title":"A prospective study of survival and prognostic indicators of systemic lupus erythematosus in a southern Chinese population","volume":"39","author":"Mok","year":"2000","journal-title":"Rheumatology (Oxford)"},{"key":"10.1136\/ard.61.12.1065_bib29","first-page":"539","article-title":"Causes of death in Korean patients with systemic lupus erythematosus: a single center retrospective study","volume":"17","author":"Kim","year":"1999","journal-title":"Clin Exp Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib30","first-page":"220","article-title":"Systemic lupus erythematosus in men: a multivariate analysis of gender differences in clinical manifestations","volume":"17","author":"Ward","year":"1990","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib31","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1191\/096120398678919930","article-title":"Survival analysis of 306 European Spanish patients with systemic lupus erythematosus","volume":"7","author":"Blanco","year":"1998","journal-title":"Lupus"},{"key":"10.1136\/ard.61.12.1065_bib32","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/00005792-198905000-00002","article-title":"Outcome in systemic lupus erythematosus: a prospective study of patients from a defined population","volume":"68","author":"Jonsson","year":"1989","journal-title":"Medicine (Baltimore)"},{"key":"10.1136\/ard.61.12.1065_bib33","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1136\/ard.48.6.447","article-title":"Systemic lupus erythematosus. I. Outcome and survival: Dutch experience with 110 patients studied prospectively","volume":"48","author":"Swaak","year":"1989","journal-title":"Ann Rheum Dis"},{"key":"10.1136\/ard.61.12.1065_bib34","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/art.1780330105","article-title":"Prognosis in systemic lupus erythematosus. Negative impact of increasing age at onset, black race, and thrombocytopenia, as well as causes of death","volume":"33","author":"Reveille","year":"1990","journal-title":"Arthritis Rheum"},{"key":"10.1136\/ard.61.12.1065_bib35","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1097\/00005792-199905000-00003","article-title":"Morbidity and mortality in systemic lupus erythematosus during a 5-year period. A multicenter prospective study of 1,000 patients. European Working Party on Systemic Lupus Erythematosus","volume":"78","author":"Cervera","year":"1999","journal-title":"Medicine (Baltimore)"},{"key":"10.1136\/ard.61.12.1065_bib36","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1007\/BF01451283","article-title":"A multicentre study of 513 Danish patients with systemic lupus erythematosus. II. Disease mortality and clinical factors of prognostic value","volume":"17","author":"Jacobsen","year":"1998","journal-title":"Clin Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib37","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/0002-9343(79)91109-4","article-title":"Late onset systemic lupus erythematosus","volume":"66","author":"Baker","year":"1979","journal-title":"Am J Med"},{"key":"10.1136\/ard.61.12.1065_bib38","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/rheumatology\/38.10.953","article-title":"Systemic lupus erythematosus: clinical features in patients with a disease duration of over 10 years, first evaluation","volume":"38","author":"Swaak","year":"1999","journal-title":"Rheumatology (Oxford)"},{"key":"10.1136\/ard.61.12.1065_bib39","first-page":"373","article-title":"The Systemic Lupus International Collaborating Clinics\/American College of Rheumatology (SLICC\/ACR) Damage Index for Systemic Lupus Erythematosus International Comparison","volume":"27","author":"Gladman","year":"2000","journal-title":"J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib40","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1093\/rheumatology\/35.3.248","article-title":"SLICC\/ACR Damage Index is valid, and renal and pulmonary organ scores are predictors of severe outcome in patients with systemic lupus erythematosus","volume":"35","author":"Stoll","year":"1996","journal-title":"Br J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib41","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/rheumatology\/29.3.185","article-title":"Estimating the incidence of systemic lupus erythematosus in a defined population using multiple sources of retrieval [see comments]","volume":"29","author":"Jonsson","year":"1990","journal-title":"Br J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib42","first-page":"527","article-title":"Disease activity in systemic lupus erythematosus: report of the Consensus Study Group of the European Workshop for Rheumatology Research. I. A descriptive analysis of 704 European lupus patients. European Consensus Study Group for Disease Activity in SLE","volume":"10","author":"Vitali","year":"1992","journal-title":"Clin Exp Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib43","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1177\/096120339200100207","article-title":"The long-term clinical outcome of 56 patients with biopsy-proven lupus nephritis followed at a single center","volume":"1","author":"Derksen","year":"1992","journal-title":"Lupus"},{"key":"10.1136\/ard.61.12.1065_bib44","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1191\/096120398678920811","article-title":"End-stage renal disease in lupus: disease activity, dialysis, and the outcome of transplantation","volume":"7","author":"Stone","year":"1998","journal-title":"Lupus"},{"key":"10.1136\/ard.61.12.1065_bib45","first-page":"862","article-title":"Prognostic factors in diffuse proliferative lupus nephritis","volume":"47","author":"Abraham","year":"1999","journal-title":"J Assoc Physicians India"},{"key":"10.1136\/ard.61.12.1065_bib46","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1080\/03009749950155464","article-title":"Prognostic value of renal biopsy and clinical variables in patients with lupus nephritis and normal serum creatinine","volume":"28","author":"Jacobsen","year":"1999","journal-title":"Scand J Rheumatol"},{"key":"10.1136\/ard.61.12.1065_bib47","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1346-8138.1998.tb02416.x","article-title":"Long term follow-up of patients with systemic lupus erythematosus","volume":"25","author":"Xie","year":"1998","journal-title":"J Dermatol"},{"key":"10.1136\/ard.61.12.1065_bib48","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1191\/096120300678828226","article-title":"Detection of coronary artery disease and the role of traditional risk factors in the Hopkins lupus cohort [in process citation]","volume":"9","author":"Petri","year":"2000","journal-title":"Lupus"},{"key":"10.1136\/ard.61.12.1065_bib49","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1055\/s-0038-1650686","article-title":"Lupus anticoagulant is the strongest risk factor for both venous and arterial thrombosis in patients with systemic lupus erythematosus. Comparison between different assays for the detection of antiphospholipid antibodies [see comments]","volume":"76","author":"Horbach","year":"1996","journal-title":"Thromb Haemost"},{"key":"10.1136\/ard.61.12.1065_bib50","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1002\/1529-0131(199805)41:5<831::AID-ART9>3.0.CO;2-1","article-title":"Risk factors for ovarian failure in patients with systemic lupus erythematosus receiving cyclophosphamide therapy","volume":"41","author":"Mok","year":"1998","journal-title":"Arthritis Rheum"}],"container-title":["Annals of the Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724091623?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0003496724091623?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ard.61.12.1065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T23:37:45Z","timestamp":1737243465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0003496724091623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12]]},"references-count":50,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["S0003496724091623"],"URL":"https:\/\/doi.org\/10.1136\/ard.61.12.1065","relation":{},"ISSN":["0003-4967"],"issn-type":[{"value":"0003-4967","type":"print"}],"subject":[],"published":{"date-parts":[[2002,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Definition of risk factors for death, end stage renal disease, and thromboembolic events in a monocentric cohort of 338 patients with systemic lupus erythematosus","name":"articletitle","label":"Article Title"},{"value":"Annals of the Rheumatic Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ard.61.12.1065","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2002 Copyright 2002 by Annals of the Rheumatic Diseases, Published by Elsevier Inc. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}