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As a remission-maintaining drug, we decided to treat her with subcutaneous immunoglobulin (CSL Behring) at 0.2\u2005g\/kg\/week at doses higher than usually employed in replacement therapy in CVID. At 3-year follow-up, the response to treatment was good. No relapses occurred. Our case suggests the effectiveness and safety of subcutaneous immunoglobulin in maintaining remission and in sparing prednisone in a woman with recurrent myelitis associated with CVID.<\/jats:p>","DOI":"10.1136\/bcr-01-2012-5637","type":"journal-article","created":{"date-parts":[[2012,8,9]],"date-time":"2012-08-09T13:08:04Z","timestamp":1344517684000},"page":"bcr0120125637","source":"Crossref","is-referenced-by-count":7,"title":["Recurrent myelitis in common variable immunodeficiency successfully managed with high-dose subcutaneous immunoglobulin"],"prefix":"10.1136","volume":"2012","author":[{"given":"Maria Giovanna","family":"Danieli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Pettinari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Marinangeli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Logullo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,8,9]]},"reference":[{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2007.03432.x"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.2","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-007-9075-1"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2011.05.018"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2009.04.005"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.5","doi-asserted-by":"publisher","DOI":"10.1006\/clim.2001.5140"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2004.02.001"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.7","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-008-0898-3"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.8","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-009-8155-9"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.9","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-007-0561-4"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2011.00330.x"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2008.04.012"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2011.01.002"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.13","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.8.5571"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.14","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000101715.32569.1A"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2011.01.006"},{"key":"2025042702505006000_2012.aug07_1.bcr0120125637.16","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2010.09.004"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-01-2012-5637","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:51:00Z","timestamp":1745747460000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-01-2012-5637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,9]]},"references-count":16,"alternative-id":["10.1136\/bcr-01-2012-5637"],"URL":"https:\/\/doi.org\/10.1136\/bcr-01-2012-5637","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,9]]}}}