{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:00:52Z","timestamp":1762866052229,"version":"3.40.4"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"published-print":{"date-parts":[[2012]]},"abstract":"<jats:p>An elderly gentleman, who had 12\u2005years earlier been successfully treated for colon cancer, presented with fever, rigours, right upper quadrant abdominal pain and tenderness. A CT of the abdomen revealed a colonic mass distal to the hepatic flexure with multiple gas locules and a walled off perforation. He underwent a right hemicolectomy. Histology confirmed multifocal colonic adenocarcinoma. His admission blood cultures grew<jats:italic>Clostridium septicum<\/jats:italic>. A week postoperatively he developed intermittent fevers and abdominal pain. Repeat CT revealed an abdominal collection adjacent to the new anastomosis, but more importantly, a sharply shouldered aneurysmal dilation of the infra-renal abdominal aorta. These findings prompted immediate surgical drainage of the collection, repair of the anastomostic leak, resection of the infected aortic aneurysm and replacement with a tube graft. This case highlights the clinical significance of<jats:italic>C septicum<\/jats:italic>bacteraemia: its association with occult colonic malignancy and with mycotic aneurysm formation. Clostridia isolated from blood cultures should not be dismissed as contaminants but fully identified to ensure appropriate patient management.<\/jats:p>","DOI":"10.1136\/bcr-2012-006167","type":"journal-article","created":{"date-parts":[[2012,9,7]],"date-time":"2012-09-07T12:03:33Z","timestamp":1347019413000},"page":"bcr2012006167","source":"Crossref","is-referenced-by-count":9,"title":["<i>Clostridium septicum<\/i>sepsis and its implications"],"prefix":"10.1136","volume":"2012","author":[{"given":"Muhammad","family":"Khalid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeka","family":"Lazarus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian CJW","family":"Bowler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris","family":"Darby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,9,7]]},"reference":[{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-1433.2001.02231.x"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(05)80023-6"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.3","first-page":"245","article-title":"Invasive Clostridium septicum infection in association with colorectal carcinoma","volume":"37","author":"Lorimer","year":"1994","journal-title":"Can J Surg"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.4","first-page":"30","article-title":"Clostridium septicum infection and associated malignancy","volume":"68","author":"Kornbluth","year":"1989","journal-title":"Report of 2 Cases and Rev Literature Medicine (Baltimore)"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.5","doi-asserted-by":"crossref","first-page":"248453","DOI":"10.1155\/2011\/248453","article-title":"Clostridium septicum sepsis and colon carcinoma: report of 4 cases","volume":"2011","author":"Mao","year":"2011","journal-title":"Case Rep Med"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.6","doi-asserted-by":"crossref","first-page":"121728","DOI":"10.1155\/2010\/121728","article-title":"Clostridium septicum aortitis and cecal adenocarcinoma","volume":"2010","author":"Moseley","year":"2010","journal-title":"Case Report Med"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.7","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-7-73"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(03)00612-8"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.9","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-003-1009-0"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.10","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.2214\/ajr.183.5.1831316","article-title":"Clostridium septicum infrarenal aortitis secondary to occult cecal adenocarcinoma","volume":"183","author":"Rucker","year":"2004","journal-title":"AJR Am J Roentgenol"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.11.058"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmv.2011.08.002"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.13","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.090946"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.14","doi-asserted-by":"publisher","DOI":"10.1016\/0163-4453(93)95595-A"},{"key":"2025042703071076000_2012.sep05_2.bcr2012006167.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2003.10.030"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-006167","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T10:07:17Z","timestamp":1745748437000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-006167"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"references-count":15,"alternative-id":["10.1136\/bcr-2012-006167"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-006167","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2012]]}}}