{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T17:48:19Z","timestamp":1759513699098,"version":"3.40.4"},"reference-count":7,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:title\/><jats:p>Primary malignant melanoma of the lacrimal sac is extremely rare. It is usually diagnosed at an advanced stage after excision or biopsy of a tumour. We treated a 59-year-old man with tearing and bloody discharge from the right eye. Clinical examination revealed a firm, localised mass at the inner canthus consistent with a lacrimal sac swelling. Sac washout demonstrated obstruction to entry into the lacrimal sac with a reflux of blood-stained fluid. The pathological findings and the immunohistochemical studies showed a malignant melanoma of the lacrimal sac. We performed radical surgery and radiation therapy. Follow-up 4\u2005months after surgery revealed no evidence of recurrence. Because this tumour often presents with symptoms similar to dacryocystitis and may masquerade as a chronic dacryocystitis, ophthalmologists should be aware of this disease entity when encountered with patients with epiphora and mass in the medial canthal area.<\/jats:p>","DOI":"10.1136\/bcr-2012-006349","type":"journal-article","created":{"date-parts":[[2012,8,13]],"date-time":"2012-08-13T14:12:49Z","timestamp":1344867169000},"page":"bcr2012006349","source":"Crossref","is-referenced-by-count":11,"title":["Primary malignant melanoma of the lacrimal sac"],"prefix":"10.1136","volume":"2012","author":[{"given":"Yang-Jun","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shao-Jun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,8,13]]},"reference":[{"key":"2025042702513474000_2012.aug09_1.bcr2012006349.1","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-008-1740-0"},{"key":"2025042702513474000_2012.aug09_1.bcr2012006349.2","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0b013e31814db537"},{"key":"2025042702513474000_2012.aug09_1.bcr2012006349.3","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2006.21.4.248"},{"key":"2025042702513474000_2012.aug09_1.bcr2012006349.4","doi-asserted-by":"publisher","DOI":"10.1159\/000076146"},{"key":"2025042702513474000_2012.aug09_1.bcr2012006349.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2005.01.012"},{"key":"2025042702513474000_2012.aug09_1.bcr2012006349.6","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1997.232"},{"key":"2025042702513474000_2012.aug09_1.bcr2012006349.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(99)90038-8"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-006349","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:51:43Z","timestamp":1745747503000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-006349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,13]]},"references-count":7,"alternative-id":["10.1136\/bcr-2012-006349"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-006349","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2012,8,13]]}}}