{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T18:22:08Z","timestamp":1747074128388,"version":"3.40.4"},"reference-count":3,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Eyelid sebaceous carcinoma is a rare tumour with slow growth and it is one of the most aggressive malignancies of the eyelid. Death rate can reach 6%. The diagnosis is often delayed because it is confused with other periocular lesions. The authors describe a case with atypical presentation, regarding rapid growth rate and exophytic aspect. Female, 78\u2005years, presenting lower eyelid tumour with 4\u2005months of evolution. Ophthalmological examination showed a tarsal exophytic tumour (22\u2005mm), non-adherent to bulbar conjunctiva. She was medicated topically for 3\u2005months, with the diagnosis of chalazio. Total excision was performed for histological diagnosis. After diagnosis of sebaceous carcinoma with specific immunohistochemical markers, and without free tumour surgical limits, a second surgery was performed with a pentagon entire thickness excision. Being a rare tumour but with a considerable morbidity and mortality; early diagnosis and treatment is essential for a good prognosis and preservation of visual function.<\/jats:p>","DOI":"10.1136\/bcr-2012-006430","type":"journal-article","created":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T15:01:26Z","timestamp":1351782086000},"page":"bcr2012006430","source":"Crossref","is-referenced-by-count":1,"title":["Atypical \u2018benign behaviour\u2019 of eyelid sebaceous carcinoma"],"prefix":"10.1136","volume":"2012","author":[{"given":"Samuel","family":"Alves","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filipe","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mara","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o","family":"Cabral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,11,1]]},"reference":[{"key":"2025042707275465000_2012.oct31_1.bcr2012006430.1","unstructured":"Shields JA Shields CL . Sebaceous gland tumors. In: Shields JA Shields CL , eds. Atlas of eyelid and conjunctival tumors. Philadelphia, PA: Lippincott Williams and Wilkins, 1999:39\u201340."},{"key":"2025042707275465000_2012.oct31_1.bcr2012006430.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2004.07.031"},{"key":"2025042707275465000_2012.oct31_1.bcr2012006430.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2004.12.008"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-006430","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:28:04Z","timestamp":1745764084000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-006430"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,1]]},"references-count":3,"alternative-id":["10.1136\/bcr-2012-006430"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-006430","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2012,11,1]]}}}