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The goals of treatment were to promptly reduce anxiety, minimise use of sedating pharmacotherapy, promote lucidity and prolong anxiety-free state thereby allowing time for important family interactions. Prompt, sustained relief of severe anxiety was necessary to achieve comfort at the end of life. Skilled additions of psychological therapies (eye movement desensitisation reprocessing, clinical hypnosis and breathing exercises) with combined pharmacotherapy (mirtazepine and quetiapine) led to control of anxiety and reduction of post-traumatic stress.<\/jats:p>","DOI":"10.1136\/bcr-2012-006800","type":"journal-article","created":{"date-parts":[[2012,10,9]],"date-time":"2012-10-09T08:37:58Z","timestamp":1349771878000},"page":"bcr2012006800","source":"Crossref","is-referenced-by-count":10,"title":["Challenges in management of complex panic disorder in a palliative care setting"],"prefix":"10.1136","volume":"2012","author":[{"given":"Itoro","family":"Udo","sequence":"first","affiliation":[{"name":"Liaison Psychiatry, Roseberry Park Hospital, Tees, Esk, Wear Valleys NHS Foundation Middlesbrough Trust, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Gash","sequence":"additional","affiliation":[{"name":"Liaison Psychiatry, Thatchell Center, University Hospital of North Tees, Tees, Esk, Wear Valleys NHS Foundation Trust, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2012,10,9]]},"reference":[{"key":"2025082623551473000_2012.oct08_1.bcr2012006800.1","unstructured":"Tees, Esk, Wear Valleys NHS Foundation Trust. 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