{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:48:56Z","timestamp":1778546936045,"version":"3.51.4"},"reference-count":27,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>The following report describes a previously healthy 2-year-old girl with herpes zoster ophthalmicus (HZO). The child presented with a painless vesicular skin eruption covering the left forehead. There was only a history of household exposure to varicella zoster virus (VZV) and the child had not been vaccinated against VZV. PCR assays on vesicular fluid identified VZV DNA. Treatment with acyclovir was started early in the clinical course. In addition, the girl was treated with locally administered ophthalmological acyclovir ointment. Besides some dermal excoriations, a complete resolution of the HZO was achieved without sequelae.<\/jats:p>","DOI":"10.1136\/bcr-2012-007015","type":"journal-article","created":{"date-parts":[[2012,10,30]],"date-time":"2012-10-30T17:00:22Z","timestamp":1351616422000},"page":"bcr2012007015","source":"Crossref","is-referenced-by-count":11,"title":["Herpes zoster ophthalmicus in an otherwise healthy 2-year-old child"],"prefix":"10.1136","volume":"2012","author":[{"given":"Marijn","family":"Soeteman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rick P P","family":"Willems","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamiu O","family":"Busari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,10,30]]},"reference":[{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(86)80875-7"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.2","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1542\/peds.76.4.512","article-title":"Epidemiology of herpes zoster in children and adolescents: a population-based study","volume":"76","author":"Guess","year":"1985","journal-title":"Pediatrics"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.3","doi-asserted-by":"publisher","DOI":"10.1080\/080352598750014139"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.4","doi-asserted-by":"publisher","DOI":"10.1111\/j.0736-8046.2004.21104.x"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2005.06.009"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2006.03.059"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2008.10.006"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.8","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3129\/can j ophthalmol.06-117","article-title":"Herpes zoster ophthalmicus and sixth nerve palsy in a pediatric patient","volume":"42","author":"Liao","year":"2007","journal-title":"Can J Ophthalmol"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.9","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1097\/01.inf.0000160989.09263.54","article-title":"Varicella zoster virus encephalitis in a previously healthy 5-year-old child with herpes zoster ophthalmicus","volume":"24","author":"Ofek-Shlomai","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.10","doi-asserted-by":"publisher","DOI":"10.1097\/01.inf.0000126901.88982.32"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2009.04.035"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.12","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e31815cb239"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2003.08.006"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.14","doi-asserted-by":"publisher","DOI":"10.1053\/spid.2002.29753"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.15","doi-asserted-by":"crossref","unstructured":"Gnann Jr, JW . Antiviral therapy of varicella-zoster virus infections. In: Arvin A, Campadelli-Fiume G, Mocarski E, Moore PS, Roizman B, Whitley R, Yamanishi K, eds. Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis. Cambridge:Cambridge University Press, 2007:1175\u201391.","DOI":"10.1017\/CBO9780511545313.066"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.16","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200111000-00014"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.17","first-page":"373","article-title":"Treatment of herpes zoster","volume":"54","author":"Opstelten","year":"2008","journal-title":"Can Fam Physician"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111283252203"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.19","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1994.170"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.20","doi-asserted-by":"publisher","DOI":"10.1086\/522631"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2010.02352.x"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.22","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181ddefb6"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.23","doi-asserted-by":"publisher","DOI":"10.3341\/kjo.2010.24.2.126"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.24","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2633"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.25","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181ddef9e"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.26","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-002-0981-1"},{"key":"2025042707265831000_2012.oct30_1.bcr2012007015.27","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-0567"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-007015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:27:05Z","timestamp":1745764025000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-007015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,30]]},"references-count":27,"alternative-id":["10.1136\/bcr-2012-007015"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-007015","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,30]]}}}