{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T11:10:12Z","timestamp":1756293012570,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>In this case report, we present a patient with rare diagnosis of amyotrophic lateral sclerosis (ALS). In this patient, four different neurological disorders were diagnosed in a short-time period of 8\u2005months. The first three diagnoses, chronic low back and leg pain, a left frontal gemistocytic astrocytoma WHO grade 2 and suspected Lyme's disease, could not fully explain the signs of physical examination. Finally, the diagnosis of ALS could reduce these signs to the same denominator.<\/jats:p>","DOI":"10.1136\/bcr-2012-007018","type":"journal-article","created":{"date-parts":[[2013,1,10]],"date-time":"2013-01-10T09:31:22Z","timestamp":1357810282000},"page":"bcr2012007018","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic pathway to amyotrophic lateral sclerosis (ALS): the significance of Babinski's sign in a unique patient and the necessity for a multidisciplinary approach"],"prefix":"10.1136","volume":"2013","author":[{"given":"Vincent","family":"Bulthuis","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marielle","family":"Vlooswijk","sequence":"additional","affiliation":[{"name":"Department of Neurology, Maastricht University Medical Center, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henk van","family":"Santbrink","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Schijns","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,1,9]]},"reference":[{"key":"2025082703340496000_2013.jan09_1.bcr2012007018.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2009.11.016"},{"key":"2025082703340496000_2013.jan09_1.bcr2012007018.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60944-1"},{"key":"2025082703340496000_2013.jan09_1.bcr2012007018.3","doi-asserted-by":"publisher","DOI":"10.1038\/ng0394-267"},{"key":"2025082703340496000_2013.jan09_1.bcr2012007018.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61156-7"},{"key":"2025082703340496000_2013.jan09_1.bcr2012007018.5","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000326585.59428.df"},{"key":"2025082703340496000_2013.jan09_1.bcr2012007018.6","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181b87983"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-007018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:34:15Z","timestamp":1756290855000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-007018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,9]]},"references-count":6,"alternative-id":["10.1136\/bcr-2012-007018"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-007018","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,1,9]]}}}