{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T13:54:33Z","timestamp":1770990873195,"version":"3.50.1"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 40-year-old healthy manual labourer from a malaria endemic area with no known risk factors for atherosclerotic coronary vascular disease was admitted to our hospital with a history of fever with chills and rigours. Physical examination revealed tachypnoea and icterus. Peripheral smear showed trophozoites of <jats:italic>Plasmodium vivax<\/jats:italic> and thrombocytopaenia. The patient was administered artesunate. Six hours after admission, he complained of severe substernal chest pain. A 12-lead ECG revealed ST elevations in leads I, II and aVL. Troponin T and creatine kinase MB were elevated and the random blood sugar was 49\u2005mg%. Echocardiogram revealed left ventricle lateral wall hypokinesia. Hypoglycaemia was corrected. A provisional diagnosis of acute coronary syndrome as a complication of malaria or its treatment was made. He was treated with low molecular weight heparin and nitrates. The patient improved symptomatically. A repeat ECG was normal.<\/jats:p>","DOI":"10.1136\/bcr-2012-007275","type":"journal-article","created":{"date-parts":[[2012,11,27]],"date-time":"2012-11-27T12:53:18Z","timestamp":1354020798000},"page":"bcr2012007275","source":"Crossref","is-referenced-by-count":6,"title":["Malaria and the heart"],"prefix":"10.1136","volume":"2012","author":[{"given":"Smitha","family":"Bhat","sequence":"first","affiliation":[{"name":"Department of Medicine, Father Muller Medical College, Mangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayaprakash","family":"Alva","sequence":"additional","affiliation":[{"name":"Department of Medicine, Father Muller Medical College, Mangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krithika","family":"Muralidhara","sequence":"additional","affiliation":[{"name":"Department of Medicine, Father Muller Medical College, Mangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayid","family":"Fahad","sequence":"additional","affiliation":[{"name":"Department of Medicine, Father Muller Medical College, Mangalore, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,11,27]]},"reference":[{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.1","unstructured":"White NJ Breman JG . Malaria. In: Fauci, Kasper, Hauser, Jameson, Loscalzo Longo. Harrison's principles of internal medicine. New York, USA: McGraw Hill, 2012."},{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.2","doi-asserted-by":"crossref","first-page":"194","DOI":"10.4269\/ajtmh.2009.80.194","article-title":"Severe Plasmodium vivax malaria: a report on serial cases from Bikaner in northwestern India","volume":"80","author":"Kochar","year":"2009","journal-title":"Am J Trop Med Hyg"},{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.3","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1007\/BF00180283","article-title":"Cardiac involvement during and after malaria","volume":"70","author":"Franzen","year":"1992","journal-title":"Clin Invest"},{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(96)90241-2"},{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.5","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-8-277"},{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.2310\/7060.2001.22133","article-title":"Myocarditis associated with Plasmodium falciparum malaria: a case report and a review of the literature","volume":"8","author":"Mohsen","year":"2001","journal-title":"J Travel Med"},{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.7","doi-asserted-by":"publisher","DOI":"10.4103\/0974-777X.59258"},{"key":"2025082804000341000_2012.nov22_2.bcr2012007275.8","unstructured":"Murray CJL Lopez AP . (eds) The global burden of disease: a comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020. Switzerland, Geneva: World Health Organization, 1996."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-007275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:00:26Z","timestamp":1756378826000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-007275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,27]]},"references-count":8,"alternative-id":["10.1136\/bcr-2012-007275"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-007275","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,27]]}}}