{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:10:06Z","timestamp":1745745006415,"version":"3.40.4"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Graves ophthalmopathy (GO) is commonly associated with hyperthyroidism, however its coexistence with hypothyroidism is seen uncommonly in 5% of cases. The ophthalmic signs in GO are usually bilaterally symmetrical, however in 10\u201315% of cases patients may present asymmetrically. The ophthalmic signs in GO are commonly seen with other systemic features of thyroid disease, however when a patient present with asymmetric ophthalmic signs in the absence of other thyroid manifestations, it is difficult to consider the possibility of thyroid disorder, which may result in delayed diagnosis and further progression of disease. Here, we report a case of 22-year-old man who presented with progressive painless bulging of right eye without other features of thyroid disease which on workup was diagnosed as a case of autoimmune hypothyroidism.<\/jats:p>","DOI":"10.1136\/bcr-2012-007485","type":"journal-article","created":{"date-parts":[[2013,1,4]],"date-time":"2013-01-04T08:09:17Z","timestamp":1357286957000},"page":"bcr2012007485","source":"Crossref","is-referenced-by-count":1,"title":["Asymmetric graves ophthalmopathy as a sole manifestation of autoimmune hypothyroidism"],"prefix":"10.1136","volume":"2013","author":[{"given":"Sudhir Kumar","family":"Verma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirdesh","family":"Jain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameer","family":"Saraf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailesh Kumar","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,1,3]]},"reference":[{"key":"2025042701324547000_2013.jan03_1.bcr2012007485.1","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/S0002-9394(14)70276-4","article-title":"Clinical features of Graves\u2019 ophthalmopathy in an incidence cohort","volume":"121","author":"Bartley","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"2025042701324547000_2013.jan03_1.bcr2012007485.2","first-page":"44","article-title":"Basic and clinical science course","volume":"7","author":"Graves ophthalmopathy","year":"2002","journal-title":"Am Acad Ophthalmol"},{"doi-asserted-by":"publisher","key":"2025042701324547000_2013.jan03_1.bcr2012007485.3","DOI":"10.1097\/01.IOP.0000124675.80763.5A"},{"key":"2025042701324547000_2013.jan03_1.bcr2012007485.4","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S0002-9394(14)70439-8","article-title":"Chronology of Graves\u2019 ophthalmopathy in an incidence cohort","volume":"121","author":"Bartley","year":"1996","journal-title":"Am J Ophthalmol"},{"doi-asserted-by":"crossref","unstructured":"Fatourechi V . Pretibial myxedema (thyroid dermopathy). In: Heymann WR , ed. Kindle edn. Thyroid disorder with cutaneous manifestations. London: Springer, 2008:107.","key":"2025042701324547000_2013.jan03_1.bcr2012007485.5","DOI":"10.1007\/978-1-84800-187-9_10"},{"doi-asserted-by":"publisher","key":"2025042701324547000_2013.jan03_1.bcr2012007485.6","DOI":"10.1210\/jc.80.9.2830"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-007485","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T08:32:52Z","timestamp":1745742772000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-007485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,3]]},"references-count":6,"alternative-id":["10.1136\/bcr-2012-007485"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-007485","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,1,3]]}}}