{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:10:06Z","timestamp":1756368606463,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Cerebral cavernous malformation (CCM) in infants tends to have genetic predisposition. These cavernomas have a progressive course of events and associated neurological symptoms with increase in age. They most commonly present with seizure and syndrome of increased intracranial pressure comprising of headache, vomiting and focal neurological signs. We describe a case of a 7-month-old infant who presented with an acute onset of right facial paralysis with a background of familial CCM. The CT and MRI scan revealed fresh haemorrhage in the right cerebellar and pontine cavernomas with surrounding oedema and no evidence of obstructive hydrocephalus. These two cavernomas re-bled in a week duration causing episodes of incessant crying and irritability. After discussing the pros and cons of treatment, owing to stable clinical status, the patient is currently been managed conservatively.<\/jats:p>","DOI":"10.1136\/bcr-2012-007508","type":"journal-article","created":{"date-parts":[[2012,11,30]],"date-time":"2012-11-30T11:14:12Z","timestamp":1354274052000},"page":"bcr2012007508","source":"Crossref","is-referenced-by-count":0,"title":["Unilateral facial palsy in an infant: an unusual presentation of familial multiple cerebral cavernous malformation"],"prefix":"10.1136","volume":"2012","author":[{"given":"Zaitun","family":"Zakaria","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandrasekaran","family":"Kaliaperumal","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Children's University Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Caird","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Children's University Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Sattar","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Children's University Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2012,11,30]]},"reference":[{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00014581"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.2","unstructured":"Morrison L Akers A . Cerebral cavernous malformation, familial. In: Pagon RA Bird TD Dolan CR Stephens K Adam MP .eds. GeneReview. Seattle, WA: University of Washington, 1993."},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.3","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1227\/01.NEU.0000249188.38409.03","article-title":"Spectrum of genotype and clinical manifestations in cerebral cavernous malformations","volume":"59","author":"Gault","year":"2006","journal-title":"Neurosurgery"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.4","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20947"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.01.057"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.6","doi-asserted-by":"publisher","DOI":"10.3171\/2010.5.FOCUS10119"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1673.2006.01638.x"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.8","doi-asserted-by":"publisher","DOI":"10.3171\/2010.5.FOCUS10119"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.9","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1997.87.2.0190"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.10","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2006.104.3.429"},{"key":"2025082800475326000_2012.nov29_1.bcr2012007508.11","doi-asserted-by":"publisher","DOI":"10.3171\/2009.6.PEDS0923"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-007508","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:48:00Z","timestamp":1756367280000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-007508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,30]]},"references-count":11,"alternative-id":["10.1136\/bcr-2012-007508"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-007508","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2012,11,30]]}}}