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In this study, we are presenting a literature review of related cases, and a 29-year-old man referred from the emergency department with a multiple distal ileal perforation that was diagnosed with GPA, and successfully treated with rituximab.<\/jats:p>","DOI":"10.1136\/bcr-2012-007518","type":"journal-article","created":{"date-parts":[[2013,1,23]],"date-time":"2013-01-23T05:49:43Z","timestamp":1358920183000},"page":"bcr2012007518","source":"Crossref","is-referenced-by-count":8,"title":["Rituximab seems a promising therapeutic option in granulomatosis with polyangiitis with intestinal perforation: a case report and literature review"],"prefix":"10.1136","volume":"2013","author":[{"given":"Muhammet Sait","family":"Dag","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Gaziantep University, School of Medicine, Sahinbey Medical Center, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yavuz","family":"Pehlivan","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Gaziantep University, School of Medicine, Sahinbey Medical Center, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ediz","family":"Tutar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Gaziantep University, School of Medicine, Sahinbey Medical Center, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bunyamin","family":"Kisacik","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Gaziantep University, School of Medicine, Sahinbey Medical Center, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,1,22]]},"reference":[{"key":"2025082801133261000_2013.jan22_1.bcr2012007518.1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.7326\/0003-4819-98-1-76","article-title":"Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years","volume":"98","author":"Fauci","year":"1983","journal-title":"Ann Intern Med"},{"key":"2025082801133261000_2013.jan22_1.bcr2012007518.2","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/thx.54.7.629","article-title":"Rare diseases. 3: Wegener's granulomatosis","volume":"54","author":"Langford","year":"1999","journal-title":"Thorax"},{"key":"2025082801133261000_2013.jan22_1.bcr2012007518.3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.4240\/wjgs.v2.i5.169","article-title":"Intestinal perforation as an early complication in Wegener's granulomatosis","volume":"2","author":"Samim","year":"2010","journal-title":"World J Gastrointest Surg"},{"key":"2025082801133261000_2013.jan22_1.bcr2012007518.4","doi-asserted-by":"publisher","DOI":"10.2174\/1874306400903010094"},{"key":"2025082801133261000_2013.jan22_1.bcr2012007518.5","doi-asserted-by":"crossref","first-page":"925","DOI":"10.7326\/0003-4819-123-12-199512150-00005","article-title":"The role of antineutrophil cytoplasmic antibody (c-ANCA) testing in the diagnosis of Wegener granulomatosis. 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