{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:27:55Z","timestamp":1777523275871,"version":"3.51.4"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Pulmonary veno-occlusive disease (PVOD) is a rare and challenging cause of pulmonary hypertension. Clinical presentation is non-specific, including dyspnoea, cough and fatigue. Diagnosis of PVOD is typically based on high clinical suspicion with a definitive diagnosis confirmed by histology. Our case involves a healthy 21-year-old man who developed dyspnoea on exertion at an elevated altitude during deployment to Afghanistan. His work-up included an echocardiogram, a high-resolution CT scan, V\/Q scan, pulmonary function tests with diffusion capacity, and a cardiac catheterisation with vasodilator challenge. Initially diagnosed with vasodilator responsive pulmonary arterial hypertension, an oral vasodilator was given with subsequent development of non-cardiogenic pulmonary oedema, thus confirming a clinical diagnosis of PVOD. He was medically stabilised with diuretic therapy, but developed progressive right-ventricular failure. For definitive treatment, he underwent a successful bilateral lung transplant. Explanted lung histology confirmed the diagnosis of PVOD.<\/jats:p>","DOI":"10.1136\/bcr-2012-007752","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T18:25:36Z","timestamp":1359743136000},"page":"bcr2012007752","source":"Crossref","is-referenced-by-count":5,"title":["Pulmonary veno-occlusive disease: an uncommon cause of pulmonary hypertension"],"prefix":"10.1136","volume":"2013","author":[{"given":"Kyle","family":"Masters","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,2,1]]},"reference":[{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.04.012"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.5.9912045"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.3","doi-asserted-by":"publisher","DOI":"10.1586\/ers.11.15"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2010.03.014"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.5","doi-asserted-by":"publisher","DOI":"10.1097\/00063198-199909000-00008"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra040291"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.7","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e31818193bb"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.8","doi-asserted-by":"publisher","DOI":"10.1378\/chest.118.6.1671"},{"key":"2025042701541199000_2013.feb01_1.bcr2012007752.9","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2004.02.008"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-007752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T08:54:20Z","timestamp":1745744060000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-007752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,1]]},"references-count":9,"alternative-id":["10.1136\/bcr-2012-007752"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-007752","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,1]]}}}