{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:26:56Z","timestamp":1761895616928,"version":"3.40.4"},"reference-count":6,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>We describe a case of severe traumatic brain injury with multiple facial and skull fractures where CT angiogram (CTA) failed to yield a definite result of brain death as an ancillary test. A 28-year-old man was admitted following a road traffic accident with a Glasgow Coma Score (GCS) of 3\/15 and fixed pupils. CT brain revealed uncal herniation and diffuse cerebral oedema with associated multiple facial and skull fractures. 72\u2005h later, his clinical condition remained the same with high intracranial pressure refractory to medical management. Clinical confirmation on brain death was not feasible owing to facial injuries. A CTA, performed to determine brain perfusion, yielded a \u2018false-negative\u2019 result. Skull fractures have possibly led to venous prominence in the cortical and deep venous drainage system. This point needs to be borne in mind while considering CTA as an ancillary test to confirm brain death.<\/jats:p>","DOI":"10.1136\/bcr-2012-007754","type":"journal-article","created":{"date-parts":[[2013,1,9]],"date-time":"2013-01-09T14:07:35Z","timestamp":1357740455000},"page":"bcr2012007754","source":"Crossref","is-referenced-by-count":4,"title":["Brain dead or not? CT angiogram yielding false-negative result on brain death confirmation"],"prefix":"10.1136","volume":"2013","author":[{"given":"Robyn","family":"Johnston","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chandrasekaran","family":"Kaliaperumal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Wyse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Kaar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,1,8]]},"reference":[{"key":"2025042701341676000_2013.jan08_1.bcr2012007754.1","first-page":"641","article-title":"Diagnosis of brain death using two-phase spiral CT","volume":"19","author":"Dupas","year":"1998","journal-title":"Am J Neuroradiol"},{"key":"2025042701341676000_2013.jan08_1.bcr2012007754.2","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1017\/S0317167100008544","article-title":"Brain blood flow in the neurological determination of death: Canadian expert report","volume":"35","author":"Shemie","year":"2008","journal-title":"Can J Neurol Sci"},{"key":"2025042701341676000_2013.jan08_1.bcr2012007754.3","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A1614"},{"key":"2025042701341676000_2013.jan08_1.bcr2012007754.4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1017\/S0317167100009069","article-title":"A review of ancillary tests in evaluating brain death","volume":"35","author":"Heran","year":"2008","journal-title":"Can J Neurol Sci"},{"key":"2025042701341676000_2013.jan08_1.bcr2012007754.5","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1136\/jnis.2010.002246","article-title":"Three dimensional CT angiography versus digital subtraction angiography in the detection of intracranial aneurysms in subarachnoid hemorrhage","volume":"4","author":"Prestigiacomo","year":"2010","journal-title":"J Neurointerv Surg"},{"key":"2025042701341676000_2013.jan08_1.bcr2012007754.6","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-009-9220-1"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-007754","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T08:34:24Z","timestamp":1745742864000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-007754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1,8]]},"references-count":6,"alternative-id":["10.1136\/bcr-2012-007754"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-007754","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,1,8]]}}}