{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:21:29Z","timestamp":1773922889257,"version":"3.50.1"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>We present a rare case of osseous metaplasia in the breast with no other associated breast pathology. A 46-year-old HIV-positive lady presented to the breast clinic with new onset intermittent left-sided mastalgia. Clinical examination revealed an indeterminate mass in the left breast with palpable left axillary lymphadenopathy. Mammography and ultrasonography were suggestive of a possible malignancy, with the latter also detecting the presence of abnormal nodes in the axilla. An ultrasound-guided core biopsy of the breast lesion showed only hyalinised normal breast tissue on two occasions. Owing to the diagnostic uncertainty, the patient underwent a wire-guided excision biopsy of the breast lesion, with the final histology demonstrating bone matrix deposition with viable osteocytes within lacunae and associated osteoclasts with spindle cells, consistent with osseous metaplasia. A core biopsy of the axillary lymph nodes was normal. The patient was therefore reassured and discharged from the clinic.<\/jats:p>","DOI":"10.1136\/bcr-2012-008239","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T02:13:12Z","timestamp":1360030392000},"page":"bcr2012008239","source":"Crossref","is-referenced-by-count":5,"title":["An unusual breast lump: osseous metaplasia"],"prefix":"10.1136","volume":"2013","author":[{"given":"Meera","family":"Joshi","sequence":"first","affiliation":[{"name":"Department of General Surgery, Wycombe Hospital, Bucks NHS Trust, Bucks, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dionysios D","family":"Remoundos","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Wycombe Hospital, Bucks NHS Trust, Bucks, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farid","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Wycombe Hospital, Bucks NHS Trust, Bucks, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabrielle","family":"Rees","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Wycombe Hospital, Bucks NHS Trust, Bucks, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giles","family":"Cunnick","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Wycombe Hospital, Bucks NHS Trust, Bucks, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,2,4]]},"reference":[{"key":"2025082804205318000_2013.feb04_1.bcr2012008239.1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4741.2002.08011.x"},{"key":"2025082804205318000_2013.feb04_1.bcr2012008239.2","unstructured":"Hajdu SL . 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