{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:49:27Z","timestamp":1756385367382,"version":"3.40.4"},"reference-count":13,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>This case report describes the unusual presentation of a previously very well woman with<jats:italic>Streptococcus<\/jats:italic><jats:italic>agalactiae<\/jats:italic>endocarditis in the emergency department. History, examination and preliminary laboratory and radiological investigations supported a diagnosis of acalculous cholecystitis, for which she was given intravenous broad spectrum antimicrobial therapy. One day following admission, the patient deteriorated and became unresponsive. Subsequent MRI of the brain revealed multiple bihemispheric cerebral emboli and a large, mobile mitral valve thrombus was visualised on her transoesophageal echocardiogram.<jats:italic>S agalactiae<\/jats:italic>was cultured from venous blood samples and her antimicrobial cover was adjusted accordingly. Despite her presumed guarded prognosis, this patient made a remarkable recovery. To our knowledge, the association of<jats:italic>S agalactiae<\/jats:italic>endocarditis with acalculous cholecystitis has not been previously described.<\/jats:p>","DOI":"10.1136\/bcr-2012-008278","type":"journal-article","created":{"date-parts":[[2013,2,12]],"date-time":"2013-02-12T07:37:58Z","timestamp":1360654678000},"page":"bcr-2012-008278","source":"Crossref","is-referenced-by-count":4,"title":["<i>Streptococcus agalactiae<\/i>endocarditis presenting as acalculous cholecystitis in a previously well woman"],"prefix":"10.1136","volume":"2013","author":[{"given":"Linda","family":"Brewer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda Hanora","family":"Lavan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Cullen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Duggan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,2,11]]},"reference":[{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra010082"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.333.7563.334"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.3","doi-asserted-by":"publisher","DOI":"10.1086\/340538"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.4","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.17.2056"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.5","doi-asserted-by":"crossref","first-page":"e182","DOI":"10.1016\/j.ijid.2011.11.008","article-title":"Group B Streptococcus infections in non-pregnant adults: the role of immunosuppression","volume":"16","author":"Sunkara","year":"2012","journal-title":"Int J Infect Dis"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2010.04.005"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(03)00444-7"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.8","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.repc.2012.01.017","article-title":"Streptococcus agalactiae endocarditis","volume":"31","author":"Machado","year":"2012","journal-title":"Rev Port Cardiol"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.9","first-page":"21","article-title":"Streptococcus agalactiae (Group B) endocarditis. A description of 12 cases and review of the literature","volume":"3","author":"Scully","year":"1987","journal-title":"Infection"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.10","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e318245cc21"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.11","doi-asserted-by":"crossref","unstructured":"Cheng HL Lin WC Shih PY . Streptococcus agalactiae infective endocarditis with large vegetation in a patient with underlying protein S deficiency. Infection 2012. (Epub ahead of print) PMID:23001489.","DOI":"10.1007\/s15010-012-0334-6"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.12","first-page":"285","article-title":"Staphylococcus aureus cholecystitis: a report of three cases with review of the literature","volume":"75","author":"Merchant","year":"2002","journal-title":"Yale J Biol Med"},{"key":"2025042701584701000_2013.feb11_1.bcr-2012-008278.13","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2008.603"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-008278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T08:58:55Z","timestamp":1745744335000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-008278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,11]]},"references-count":13,"alternative-id":["10.1136\/bcr-2012-008278"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-008278","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,2,11]]}}}