{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T09:10:10Z","timestamp":1745745010614,"version":"3.40.4"},"reference-count":14,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A young male patient reported for evaluation of progressive easy fatigability, accompanied by a recent history of recurrent haemoptysis. His clinical examination was unremarkable except for evidence of pulmonary arterial hypertension (PAH). Routine investigations (haemogram, coagulogram, serological tests for connective tissue disorders and a sputum Ziehl Neelsen stain for acid-fast bacilli) were normal. Two-dimensional echocardiography suggested PAH (pulmonary artery systolic pressure\u201467\u2005mm\u2005Hg), whereas the 64-slice spiral CT pulmonary angiogram showed a dilated main pulmonary artery along with bilateral arteriovenous malformations. Cardiac catheterisation performed subsequently confirmed the presence of PAH. On the basis of the above findings, a diagnosis of hereditary haemorrhagic telangiectasia (HHT) complicated with PAH was made, and the patient was started on oral sildenafil therapy to which he responded well. This rare complication of HHT, which requires a high degree of suspicion for diagnosis, is discussed.<\/jats:p>","DOI":"10.1136\/bcr-2012-008352","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T18:25:36Z","timestamp":1359743136000},"page":"bcr2012008352","source":"Crossref","is-referenced-by-count":7,"title":["Pulmonary hypertension in a patient with hereditary haemorrhagic telangiectasia"],"prefix":"10.1136","volume":"2013","author":[{"given":"Davinder","family":"Chadha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay","family":"Handa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhishek","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,2,1]]},"reference":[{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.1","first-page":"1322","article-title":"Epistaxis repetees chez un sujet porteur de petits angiomes cutanes et muquez","volume":"13","author":"Rendu","year":"1896","journal-title":"Gaz H\u00f4pitaux"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.2","first-page":"333","article-title":"On a family form of recurring epistaxis, associated with multiple telangiectases of the skin and mucous membranes","volume":"12","author":"Osler","year":"1901","journal-title":"Bull Johns Hopkins Hosp"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.3","first-page":"160","article-title":"Multiple hereditary developmental angiomata (telangiectases) of the skin and mucous membranes associated with recurring hemorrhages","volume":"2","author":"Weber","year":"1907","journal-title":"Lancet"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.4","first-page":"785","article-title":"Hereditary hemorrhagic telangiectasia: diagnosis and management","volume":"82","author":"Olitsky","year":"2010","journal-title":"Am Fam Physician"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.5","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00061308"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.04.012"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.7","unstructured":"Raimondi A Blanco I Pomares X . 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Arch Bronconeumol 2012 Jun 22 (Epub ahead of print) PMID: 22727716."},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.8","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1002\/ajmg.a.32468","article-title":"BMPR2 mutation in a patient with pulmonary arterial hypertension and suspected hereditary hemorrhagic telangiectasia","volume":"146A","author":"Rigelsky","year":"2008","journal-title":"Am J Med Genet A"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.9","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-1402"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.10","doi-asserted-by":"publisher","DOI":"10.1159\/000103205"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.11","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1215111"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.12","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-010-0079-z"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.13","doi-asserted-by":"publisher","DOI":"10.1590\/S0066-782X2010000100007"},{"key":"2025042701541555000_2013.feb01_1.bcr2012008352.14","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00139009"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-008352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T08:54:23Z","timestamp":1745744063000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-008352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,1]]},"references-count":14,"alternative-id":["10.1136\/bcr-2012-008352"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-008352","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,2,1]]}}}