{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:19:37Z","timestamp":1758637177228,"version":"3.40.4"},"reference-count":15,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>This case illustrates an overlooked metastatic lung carcinoma to the orbit. The rapid onset of symptoms and oedema mimicked a cellulitis. The patient was initially treated with a broad-spectrum topical and intravenous antibiotic therapy. The white blood cell count (WBC) and C reactive protein (CRP) were normal. Compressive optic neuropathy and serous retinal detachment ensued. The initial chest x-ray revealed lung shadows; however, this was not reviewed. Eventually, CT of the chest was organised and showed a lung mass. The management of such a case remains a challenge for the uninitiated, and high index of suspicion is required to ensure early appropriate management. Despite complete resolution of the swelling with sequential chemotherapy (cisplatin and etoposide) and radiotherapy, the visual prognosis remained grim.<\/jats:p>","DOI":"10.1136\/bcr-2012-008410","type":"journal-article","created":{"date-parts":[[2013,4,24]],"date-time":"2013-04-24T03:55:59Z","timestamp":1366775759000},"page":"bcr2012008410","source":"Crossref","is-referenced-by-count":1,"title":["A case of misconstrue proptosis"],"prefix":"10.1136","volume":"2013","author":[{"given":"Patrick J T","family":"Chiam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian W-M","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan D","family":"Hubbard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suboda","family":"Weerasinghe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,4,23]]},"reference":[{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.1","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1159\/000334784","article-title":"Exophthalmos as a first manifestation of small cell lung cancer: a long-term follow-up","volume":"2013","author":"Konoglou","year":"2011","journal-title":"Case Rep Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.2","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1055\/s-2000-10383","article-title":"Diplopia as first symptom of a bronchogenic carcinoma","volume":"2013","author":"Velten","year":"2000","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.3","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0161-6420(90)32534-4","article-title":"Clinical characteristics of metastatic orbital tumors","volume":"2013","author":"Goldberg","year":"1990","journal-title":"Ophthalmology"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.4","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1136\/bjo.81.5.386","article-title":"Orbital metastases: diagnosis and course","volume":"2013","author":"Char","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.5","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/ICU.0b013e3282c5077c","article-title":"Metastatic tumors of the orbit and ocular adnexa","volume":"2013","author":"Ahmad","year":"2007","journal-title":"Curr Opin Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.6","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1001\/archopht.1974.01010010286003","article-title":"Carcinoma metastatic to the eye and orbit. I. A clinicopathologic study of 227 cases","volume":"2013","author":"Ferry","year":"1974","journal-title":"Arch Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.7","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1001\/archopht.1971.00990050675005","article-title":"The incidence of ocular metastatic carcinoma","volume":"2013","author":"Bloch","year":"1971","journal-title":"Arch Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.8","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1136\/bjo.80.2.125","article-title":"Frequency of ocular metastases in patients dying of cancer in eye bank populations","volume":"2013","author":"Eliassi-Rad","year":"1996","journal-title":"Br J Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.9","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/0002-9394(67)91297-4","article-title":"Tumor metastasis to the eye. I. Incidence in 213 adult patients with generalized malignancy","volume":"2013","author":"Albert","year":"1967","journal-title":"Am J Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.10","first-page":"51","article-title":"Secondary and metastatic tumors of the orbit","volume":"2013","author":"Jakobiec","year":"1998","journal-title":"Clin Opthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.11","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1002\/1097-0142(197609)38:3<1326::AID-CNCR2820380336>3.0.CO;2-#","article-title":"Carcinoma metastatic to the eye and orbit. III. A clinicopathologic study of 28 cases metastatic to the orbit","volume":"2013","author":"Font","year":"1976","journal-title":"Cancer"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.12","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/S0161-6420(79)35393-3","article-title":"Diagnosis and management of cancer metastatic to the uvea: a study of 70 cases","volume":"2013","author":"Stephens","year":"1979","journal-title":"Ophthalmology"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.13","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1001\/archopht.1987.01060090073031","article-title":"Metastatic tumors to the eye and orbit. Patient survival and clinical characteristics","volume":"2013","author":"Freedman","year":"1987","journal-title":"Arch Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.14","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0002-9394(14)77955-3","article-title":"Orbital fine-needle aspiration biopsy","volume":"2013","author":"Kennerdell","year":"1985","journal-title":"Am J Ophthalmol"},{"key":"2025042707421377000_2013.apr23_1.bcr2012008410.15","first-page":"1","article-title":"Tumors metastatic to the orbit","volume":"2013","author":"Goldberg","year":"1990","journal-title":"Surv Ophthamol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-008410","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T14:42:23Z","timestamp":1745764943000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-008410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,23]]},"references-count":15,"alternative-id":["10.1136\/bcr-2012-008410"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-008410","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,4,23]]}}}