{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T12:57:59Z","timestamp":1773320279333,"version":"3.50.1"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Primary hepatic lymphoma (PHL) is rare and represents approximately 0.016% of all cases of non-Hodgkin\u2019s lymphoma (NHL). The majority of these are B-cell NHL of diffuse large B-cell type. Primary T-cell lymphoma constitutes approximately 5\u201310% of all PHLs arising in the liver, 90% being B-cell type. Peripheral T-cell lymphoma, \u03b3\u03b4 hepatosplenic T-cell lymphoma and \u03b1\u03b2 hepatosplenic T-cell lymphoma are the common T-cell lymphomas involving hepatic parenchyma. We encountered a case presenting with gross hepatomegaly extending beyond umbilicus, mild ascites, pedal oedema, icterus and dyspnoea. Haemogram showed moderate anaemia with counts. Bone marrow aspiration showed erythroid hyperplasia with dimorphic anaemia. There was no evidence of atypical lymphoid cells in peripheral blood of bone marrow. We present a rare case of primary T-cell lymphoma presenting as primary liver involvement without splenomegaly, lymphadenopathy, bone marrow or peripheral blood involvement.<\/jats:p>","DOI":"10.1136\/bcr-2012-008467","type":"journal-article","created":{"date-parts":[[2013,4,22]],"date-time":"2013-04-22T10:30:28Z","timestamp":1366626628000},"page":"bcr2012008467","source":"Crossref","is-referenced-by-count":5,"title":["Primary T-cell lymphoma of liver"],"prefix":"10.1136","volume":"2013","author":[{"given":"S","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Clinical Hematology & Medical Oncology, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Clinical Hematology & Medical Oncology, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"AK","family":"Tripathi","sequence":"additional","affiliation":[{"name":"Department of Clinical Hematology & Medical Oncology, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,4,22]]},"reference":[{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.1","doi-asserted-by":"crossref","first-page":"617","DOI":"10.2169\/internalmedicine.50.4686","article-title":"Primary hepatic peripheral T-cell lymphoma treated with corticosteroid","volume":"2013","author":"Miyashita","year":"2011","journal-title":"Intern Med"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.2","first-page":"213","article-title":"Primary focal T-cell lymphomas of the liver: a case report and review of the literature","volume":"2013","author":"Cerban","year":"2012","journal-title":"J Gastrointestin Liver Dis"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.3","doi-asserted-by":"crossref","first-page":"273","DOI":"10.3816\/CLM.2006.n.001","article-title":"Non-Hodgkin's lymphoma involving the liver: clinical and therapeutic considerations","volume":"2013","author":"Salmon","year":"2006","journal-title":"Clin Lymphoma Myeloma"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.4","doi-asserted-by":"crossref","first-page":"150","DOI":"10.3816\/CLM.2002.n.021","article-title":"Hepatitis C virus infection and B-cell non-Hodgkin's lymphomas: more than a simple association","volume":"2013","author":"Musto","year":"2002","journal-title":"Clin Lymphoma"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.5","first-page":"553","article-title":"Primary lymphoma of the liver in the acquired immunodeficiency syndrome","volume":"2013","author":"Caccamo","year":"1986","journal-title":"Arch Pathol Lab Med"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.6","first-page":"43","article-title":"Diffuse large B cell lymphoma of the liver: immunophenotyping profile, biological properties and association with hepatitis C virus infection","volume":"2013","author":"Ehsan","year":"2010","journal-title":"Nile Liver J"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.7","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.critrevonc.2004.10.010","article-title":"Primary non-Hodgkin's lymphoma of the liver","volume":"2013","author":"Noronha","year":"2005","journal-title":"Crit Rev Oncol Hematol"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.8","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1023\/A:1008214629544","article-title":"Alternating triple therapy for the treatment of intermediate grade and immunoblastic lymphoma","volume":"2013","author":"Cabanillas","year":"1998","journal-title":"Ann Oncol"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.9","first-page":"1336","article-title":"Aggressive primary hepatic lymphoma in Chinese patients. Presentation, pathologic features and outcome","volume":"2013","author":"Lei","year":"1995","journal-title":"Cancer"},{"key":"2025082802135380000_2013.apr22_1.bcr2012008467.10","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1309\/9DAQ-PWP3-XKDG-CUTG","article-title":"Peripheral T-cell lymphoma arising in the liver","volume":"2013","author":"Stancu","year":"2002","journal-title":"Am J Clin Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2012-008467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:14:04Z","timestamp":1756372444000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2012-008467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,22]]},"references-count":10,"alternative-id":["10.1136\/bcr-2012-008467"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2012-008467","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,22]]}}}