{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:54:15Z","timestamp":1756385655009,"version":"3.44.0"},"reference-count":3,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Spontaneous non-traumatic <jats:italic>Escherichia coli<\/jats:italic> meningitis is very rare in adults. We report a case of a 48-year-old woman with Marfan's syndrome with <jats:italic>E coli<\/jats:italic> meningitis. Apparently, the relation between an increased risk of meningitis and Marfan's syndrome is not well known. This patient was discharged on intravenous \u00a0antibiotic therapy after a diagnosis of <jats:italic>E coli<\/jats:italic> meningitis without looking for the cause by imaging studies previously. Her blood cultures were negative ruling out haematogenous spread. Our work-up revealed extensive dural ectasia with intrasacral meningoceles extending into the pelvis possibly acting as a portal of entry for the bacteria into the brain from the gastrointestinal tract.<\/jats:p>","DOI":"10.1136\/bcr-2013-008592","type":"journal-article","created":{"date-parts":[[2013,3,5]],"date-time":"2013-03-05T22:28:22Z","timestamp":1362522502000},"page":"bcr2013008592","source":"Crossref","is-referenced-by-count":4,"title":["An unusual case of <i>E coli<\/i> meningitis in a patient with Marfan's syndrome"],"prefix":"10.1136","volume":"2013","author":[{"given":"Raghesh Varot","family":"Kangath","sequence":"first","affiliation":[{"name":"Scott & White Infectious Diseases Division, Texas A & M School of Medicine, Temple, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Midturi","sequence":"additional","affiliation":[{"name":"Infectious Diseases Division, Scott & White Hospital, Temple, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,3,5]]},"reference":[{"key":"2025082802261300000_2013.mar05_1.bcr2013008592.1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00009-08"},{"key":"2025082802261300000_2013.mar05_1.bcr2013008592.2","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000131212.36990.0A"},{"key":"2025082802261300000_2013.mar05_1.bcr2013008592.3","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3928\/01477447-20080201-21","article-title":"Giant anterior sacral meningocele presenting as bacterial meningitis in a previously healthy adult","volume":"31","author":"Miletic","year":"2008","journal-title":"Orthopedics"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-008592","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:26:20Z","timestamp":1756373180000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-008592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,5]]},"references-count":3,"alternative-id":["10.1136\/bcr-2013-008592"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-008592","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,3,5]]}}}