{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:34:59Z","timestamp":1787016899513,"version":"build-2736575974"},"reference-count":25,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>\n                    We present two uncommon underlying causes of a sore throat which, if missed or delayed in diagnosis, can lead to disastrous consequences. Our first case is of Lemierre's syndrome diagnosed in a 21-year-old man presenting with a 5-day history of sore throat, fever, right-sided pleuritic chest pain and bilateral pulmonary nodules on CT imaging.\n                    <jats:italic>Fusobacterium necrophorum<\/jats:italic>\n                    cultured from peripheral blood and an occluded left internal jugular vein on ultrasound lead to an eventual diagnosis. Our second case presents a 29-year-old woman with a 5-day history of sore throat, fever and right-sided pleuritic chest pain. A left-sided quinsy was diagnosed and aspirated and the patient was discharged home. She represented shortly with worsening pleuritic pain and was found to have a right-sided pleural effusion with descending mediastinitis originating from the tonsillar abscess. Delayed diagnosis resulted in open thoracotomy, decortication and prolonged intravenous antibiotics.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2013-008739","type":"journal-article","created":{"date-parts":[[2013,4,30]],"date-time":"2013-04-30T01:10:53Z","timestamp":1367284253000},"page":"bcr2013008739","source":"Crossref","is-referenced-by-count":6,"title":["Just a sore throat? Uncommon causes of significant respiratory disease"],"prefix":"10.1136","volume":"2013","author":[{"given":"Dalia","family":"Wahab","sequence":"first","affiliation":[{"name":"Department of Respiratory, Royal Brompton Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Bichard","sequence":"additional","affiliation":[{"name":"Palliative Care Department, Royal Free Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Respiratory, Royal Brompton Hospital, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhupinder","family":"Mann","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, West Middlesex University Hospital, Isleworth, Middlesex, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,4,29]]},"reference":[{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.1","first-page":"e20","article-title":"Sore throat progressing to embolic sepsis: a case of Lemierre's syndrome","volume":"2013","author":"Dirks","year":"2010","journal-title":"Can Respir J"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.2","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1086\/313970","article-title":"Human necrobacillosis, with emphasis on Lemierre's syndrome","volume":"2013","author":"Kristensen","year":"2000","journal-title":"Clin Infect Dis"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.3","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1186\/1752-1947-2-374","article-title":"Lemierre's syndrome due to community-acquired meticillin-resistant Staphylococcus aureus infection and presenting with orbital cellulitis: a case report","volume":"2013","author":"Kadhiravan","year":"2008","journal-title":"J Med Case Rep"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.4","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1128\/CMR.00011-07","article-title":"Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre's syndrome","volume":"2013","author":"Riordan","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.5","first-page":"199","article-title":"Peritonsillar abscess","volume":"2013","author":"Galioto","year":"2008","journal-title":"Am Fam Physician"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.6","first-page":"123943","article-title":"Variant of Lemierre's syndrome secondary to trauma","volume":"2013","author":"Bukari","year":"2010","journal-title":"Int J 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Hospital","volume":"2013","author":"Ramirez","year":"2003","journal-title":"Pediatrics"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.10","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3904\/kjim.2007.22.3.211","article-title":"Lemierre syndrome: a case of postanginal sepsis","volume":"2013","author":"Seo","year":"2007","journal-title":"Korean J Intern Med"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.7883\/yoken.JJID.2009.133","article-title":"Lemierre's syndrome followed by acute respiratory distress syndrome successfully rescued by antibiotics and hemoperfusion with polymyxin B-immobilized fiber","volume":"2013","author":"Takazono","year":"2009","journal-title":"Jpn J Infect Dis"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.12","doi-asserted-by":"crossref","first-page":"6658","DOI":"10.1186\/1752-1947-3-6658","article-title":"Lemierre's syndrome resulting from streptococcal induced otitis media and mastoiditis: a case report","volume":"2013","author":"Harris","year":"2009","journal-title":"J Med Case Rep"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.13","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1007\/s11606-009-1001-1","article-title":"A sore throat\u2014potentially life-threatening?","volume":"2013","author":"Li","year":"2009","journal-title":"J Gen Intern Med"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.14","doi-asserted-by":"crossref","first-page":"6397","DOI":"10.1186\/1757-1626-2-6397","article-title":"Lemierre's syndrome, re-emergence of a forgotten disease: a case report","volume":"2013","author":"Kushawaha","year":"2009","journal-title":"Cases J"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.15","first-page":"982494","article-title":"A unique case of Lemierre syndrome associated with thrombophilia in an adult and the role of anticoagulation","volume":"2013","author":"Lakshminarayana","year":"2010","journal-title":"Case Report Med"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.3349\/ymj.2007.48.1.55","article-title":"Predisposing factors of complicated deep neck infection: an analysis of 158 cases","volume":"2013","author":"Lee","year":"2007","journal-title":"Yonsei Med J"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1159\/000096715","article-title":"Parapharyngeal abscess: comprehensive management protocol","volume":"2013","author":"Oh","year":"2007","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.18","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s00405-004-0800-6","article-title":"Parapharyngeal abscess: diagnosis, complications and management in 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Laryngol"},{"key":"2025082803233822000_2013.apr29_1.bcr2013008739.25","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1017\/S0022215100133092","article-title":"Mediastinitis\u2014a rare complication of a peritonsillar abscess","volume":"2013","author":"Nielsen","year":"1996","journal-title":"J Laryngol Otol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-008739","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:23:50Z","timestamp":1756376630000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-008739"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,29]]},"references-count":25,"alternative-id":["10.1136\/bcr-2013-008739"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-008739","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,29]]}}}