{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T08:10:01Z","timestamp":1756282201517,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Infantile hypertrophic pyloric stenosis (IHPS) is a common surgical cause of vomiting, which requires surgery in infant. There is the complete or partial obstruction of pylorus due to hypertrophy of circular muscle of the pylorus leading gastric outlet obstruction. The occurrence of IHPS in dizygotic twins is rarer and the theory of genetic origin alone does not explain it. Recent literature points to the association of bottle feeding in singletons to be a major aetiological factor for this condition. Here, we present a rare case of dizygotic twins who were bottle-fed and were affected with IHPS. We review the literature and focus on the question of whether this condition in twins supports a genetic or environmental origin of IHPS.<\/jats:p>","DOI":"10.1136\/bcr-2013-008779","type":"journal-article","created":{"date-parts":[[2013,4,10]],"date-time":"2013-04-10T00:21:29Z","timestamp":1365553289000},"page":"bcr2013008779","source":"Crossref","is-referenced-by-count":3,"title":["Infantile hypertrophic pyloric stenosis in twins"],"prefix":"10.1136","volume":"2013","author":[{"given":"Vijay Kumar","family":"Kundal","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, SMS Medical College, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mufique","family":"Gajdhar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, SMS Medical College, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arvind Kumar","family":"Shukla","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, SMS Medical College, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raksha","family":"Kundal","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, SMS Medical College, Jaipur, Rajasthan, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,4,9]]},"reference":[{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.1","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1001\/jama.2010.784","article-title":"Familial aggregation and heritability of pyloric stenosis","volume":"2013","author":"Krogh","year":"2010","journal-title":"JAMA"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.2","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1001\/archpedi.1993.02160350077012","article-title":"The genetics of infantile hypertrophic pyloric stenosis: a reanalysis","volume":"2013","author":"Michel","year":"1993","journal-title":"Am J Dis Child"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.3","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1136\/jmg.6.3.233","article-title":"Inheritance of congenital pyloric stenosis","volume":"2013","author":"Carter","year":"1969","journal-title":"J Med Genet"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.4","first-page":"195","article-title":"The continuing enigma of pyloric stenosis of infancy: a review","volume":"2013","author":"Mac Mohan","year":"2006","journal-title":"Epidemiology"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.5","doi-asserted-by":"crossref","first-page":"E70","DOI":"10.1542\/peds.108.4.e70","article-title":"Parallel incidences of sudden infant death syndrome and infantile hypertrophic pyloric stenosis: a common cause?","volume":"2013","author":"Persson","year":"2001","journal-title":"Pediatrics"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.6","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1046\/j.1365-3016.1997.d01-32.x","article-title":"The epidemiology of infantile hypertrophic pyloric stenosis","volume":"2013","author":"Schechter","year":"1997","journal-title":"Paediatr Perinat Epidemiol"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.7","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1177\/000992289002901002","volume":"2013","author":"Sharma","year":"1990","journal-title":"Clin Pediatr"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.8","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1148\/radiology.178.3.1994426","article-title":"Antropyloric muscle thickness at US in infants: what is normal?","volume":"2013","author":"O'Keeffe","year":"1991","journal-title":"Radiology"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.9","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1093\/oxfordjournals.bmb.a069918","article-title":"The inheritance of congenital pyloric stenosis","volume":"2013","author":"Carter","year":"1961","journal-title":"Br Med Bull"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.10","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1001\/archpedi.1993.02160350077012","article-title":"The genetics of infantile hypertrophic pyloric stenosis. A reanalysis","volume":"2013","author":"Mitchell","year":"1993","journal-title":"Am J Dis Child"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.11","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1086\/505952","article-title":"Linkage of monogenic infantile hypertrophic stenosis to chromosome16p 12- p13 and evidence for genetic heterogeneity","volume":"2013","author":"Capon","year":"2006","journal-title":"Am J Hum Genet"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.12","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1136\/jmg.13.4.290","article-title":"Genetic analysis of pyloric stenosis suggesting a specific maternal effect","volume":"2013","author":"Kidd","year":"1976","journal-title":"J Med Genet"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.13","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1136\/bmj.325.7371.1011","article-title":"Maternal smoking and risk of hypertrophic infantile pyloric stenosis: 10 year population based cohort study","volume":"2013","author":"Sorenson","year":"2002","journal-title":"Br Med J"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1080\/0144361021000043227","article-title":"Sex ratio imbalance and birth weight in newborns with isolated hypertrophic pyloric stenosis","volume":"2013","author":"Bianca","year":"2003","journal-title":"J Obstet Gynaecol"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.15","doi-asserted-by":"crossref","first-page":"843","DOI":"10.2214\/ajr.177.4.1770843","article-title":"In vivo visualization of pyloric mucosal hypertrophy in infants with hypertrophic pyloric stenosis: is there an etiologic role?","volume":"2013","author":"Hernanz-Schulman","year":"2001","journal-title":"AJR Am J Roentgenol"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.16","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1054\/mehy.1999.1020","article-title":"Is Helicobacter pylori a cause of infantile pyloric stenosis?","volume":"2013","author":"Paulozzi","year":"2000","journal-title":"Med Hypotheses"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.17","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1056\/NEJM199208203270801","article-title":"Gastricoutlet obstruction induced by prostaglandins therapy in neonates","volume":"2013","author":"Peled","year":"1992","journal-title":"N Engl J Med"},{"key":"2025082700333880000_2013.apr09_1.bcr2013008779.18","first-page":"1","article-title":"Bottle-feeding and the risk of pyloric stenosis","volume":"2013","author":"Krogh","year":"2012","journal-title":"Pediatrics"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-008779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:33:52Z","timestamp":1756280032000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-008779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,9]]},"references-count":18,"alternative-id":["10.1136\/bcr-2013-008779"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-008779","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,4,9]]}}}