{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:08:07Z","timestamp":1781910487912,"version":"3.54.5"},"reference-count":17,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Intraocular tuberculosis (TB) infection can have different clinical manifestations including retinal vasculitis. It more frequently involves the veins and is associated with retina haemorrhages and neovascularisation. The diagnosis may be difficult and presumptive being based on clinical findings and evidence of systemic TB infection. The authors present a case of a 61-year-old woman with blurred vision and floaters in her left eye for 6\u2005years, associated with recurrent vitreous haemorrahages. A temporal branch retinal vein occlusion was presumed. Four years later her right eye was also involved. Her best-corrected visual acuity (BCVA) was 20\/50 in both eyes. Fundoscopic examination showed bilateral venous occlusion with vascular staining on fluorescein angiography suggestive of vasculitis secondary to Eales Disease (ED). The interferon gamma release assay (IGRA-QuantiFERON-TB Gold) was positive and antituberculosis treatment (ATT) was started. Her final BCVA was 20\/20 bilaterally, without recurrences over a follow-up of 15\u2005months. The use of ATT is likely to reduce recurrent vitreous haemorrhages and eliminate future recurrences.<\/jats:p>","DOI":"10.1136\/bcr-2013-008924","type":"journal-article","created":{"date-parts":[[2013,6,4]],"date-time":"2013-06-04T00:53:39Z","timestamp":1370307219000},"page":"bcr2013008924","source":"Crossref","is-referenced-by-count":6,"title":["Tubercular retinal vasculitis"],"prefix":"10.1136","volume":"2013","author":[{"given":"Maria Sara","family":"Patricio","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Hospital de Egas Moniz, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Portelinha","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital de Egas Moniz, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Picoto","family":"Passarinho","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital de Egas Moniz, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta Esteves","family":"Guedes","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Hospital de Egas Moniz, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,6,3]]},"reference":[{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00005792-198401000-00003","article-title":"Extrapulmonary tuberculosis revisited: a review of experience at Boston City and other hospitals","volume":"2013","author":"Alvarez","year":"1984","journal-title":"Medicine (Baltimore)"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.2","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0002-9394(14)70328-9","article-title":"Polymerase chain reaction for the detection of Mycobacterium tuberculosis in ocular tuberculosis","volume":"2013","author":"Kotake","year":"1994","journal-title":"Am J Ophthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.3","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1034\/j.1600-0420.1998.760609.x","article-title":"Management of presumed intraocular tuberculosis: possible role of the polymerase chain reaction","volume":"2013","author":"Gupta","year":"1998","journal-title":"Acta Ophthalmol Scand"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.4","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0161-6420(99)90068-4","article-title":"Choroidal tuberculosis diagnosed by polymerase chain reaction. A clinicopathologic case report","volume":"2013","author":"Bowyer","year":"1999","journal-title":"Ophthalmology"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.5","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/S0002-9394(14)76260-9","article-title":"Tuberculous choroiditis diagnosed by chorioretinal endobiopsy","volume":"2013","author":"Barondes","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.6","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1001\/archopht.124.12.1777","article-title":"Tuberculous uveitis: distribution of Mycobacterium tuberculosis in the retinal pigment epithelium","volume":"2013","author":"Rao","year":"2006","journal-title":"Arch Ophthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.7","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1097\/00006982-200110000-00004","article-title":"PCR-positive tubercular retinal vasculitis: clinical characteristics and management","volume":"2013","author":"Gupta A, Gupta V, Arora S","year":"2001","journal-title":"Retina"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.8","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.survophthal.2007.08.015","article-title":"Intraocular tuberculosis\u2013an update","volume":"2013","author":"Gupta","year":"2007","journal-title":"Surv Ophthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.9","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.ajo.2008.06.011","article-title":"Role of anti-tubercular therapy in uveitis with latent\/manifest tuberculosis","volume":"2013","author":"Bansal","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.10","first-page":"267","article-title":"Retinal Hemorrhages associated with epistaxis and constipation","volume":"2013","author":"Eales","year":"1880","journal-title":"Birmingham Med Rev"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.11","first-page":"41","article-title":"Primary retinal hemorrhage in young men","volume":"2013","author":"Eales","year":"1882","journal-title":"Ophthalmic Rev"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.12","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0039-6257(02)00288-6","article-title":"Eales Disease an update","volume":"2013","author":"Biswas J, Sharma T, Gopal L","year":"2002","journal-title":"Surv Ophthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.13","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1001\/archopht.1959.00940090747011","article-title":"Recurrent intraocular hemorrhage in young adults (Eales\u2019 disease)","volume":"2013","author":"Elliot","year":"1959","journal-title":"AMA Arch Opthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.14","first-page":"164","article-title":"Mycobacterium tuberculosis as a causative agent in Eales\u2019 disease; PCR based analysis of vitreous samples","volume":"2013","author":"Niazi","year":"2010","journal-title":"IDJ of PAK"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.15","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1136\/bjo.83.8.994","article-title":"Use of polymerase chain reaction in detection of Mycobacterium tuberculosis complex DNA from vitreous sample of Eales\u2019 disease","volume":"2013","author":"Biswas J, Therese L, Madhavan HN","year":"1999","journal-title":"Br J Ophthalmol"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.16","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3109\/09273948.2012.658134","article-title":"et al. Quantitative polymerase chain reaction for Mycobacterium tuberculosis in so-called Eales\u2019 disease","volume":"2013","author":"Singh","year":"2012","journal-title":"Ocul Immunol Inflamm"},{"key":"2025082801222482000_2013.jun03_1.bcr2013008924.17","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1038\/eye.2009.315","article-title":"Eales\u2019 disease: diagnosis and management","volume":"2013","author":"Das","year":"2010","journal-title":"Eye"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-008924","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:22:36Z","timestamp":1756369356000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-008924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,3]]},"references-count":17,"alternative-id":["10.1136\/bcr-2013-008924"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-008924","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,3]]}}}