{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:40Z","timestamp":1756425820230,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>An 85-year-old man was admitted to the medical intensive care unit with a 10-day history of severe breathlessness, fever and cough. The patient was known to have chronic obstructive pulmonary disease and had been receiving corticosteroids in the preceding 18\u2005months. He had been treated for tuberculosis 2.5\u2005years previously. On examination he was febrile, tachycardic with a respiratory rate of 46\/min. Auscultation revealed bilateral crepitation's and wheeze. Chest radiograph revealed patchy infiltrates on right lung. The patient developed respiratory depression and was mechanically ventilated. His sputum and endotracheal aspirates revealed <jats:italic>Nocardia brasiliensis<\/jats:italic> on culture which was found to be co-trimoxazole resistant. Once this became known imipenem was substituted for co-trimoxazole but unfortunately condition of the patient did not improve and he died following a cardiac arrest.<\/jats:p>","DOI":"10.1136\/bcr-2013-009069","type":"journal-article","created":{"date-parts":[[2013,4,17]],"date-time":"2013-04-17T23:53:45Z","timestamp":1366242825000},"page":"bcr2013009069","source":"Crossref","is-referenced-by-count":3,"title":["Emergence of co-trimoxazole resistant <i>Nocardia brasiliensis<\/i> causing fatal pneumonia"],"prefix":"10.1136","volume":"2013","author":[{"given":"Vineeta","family":"Khare","sequence":"first","affiliation":[{"name":"Department of Microbiology, Hind Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Microbiology, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himanshu","family":"D","sequence":"additional","affiliation":[{"name":"Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,4,17]]},"reference":[{"key":"2025082802262561000_2013.apr17_1.bcr2013009069.1","doi-asserted-by":"crossref","first-page":"4497","DOI":"10.1128\/JCM.41.10.4497-4501.2003","article-title":"Nocardiosis: review of clinical and laboratory experience","volume":"2013","author":"Saubolle","year":"2003","journal-title":"J Clin Microbiol"},{"key":"2025082802262561000_2013.apr17_1.bcr2013009069.2","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1128\/jcm.35.4.847-852.1997","article-title":"Comparison of agar dilution, broth microdilution, disk diffusion, E-test, and BACTEC radiometric methods for antimicrobial susceptibility testing of clinical isolates of the Nocardia asteroides complex","volume":"2013","author":"Ambaye","year":"1997","journal-title":"J Clin Microbiol"},{"key":"2025082802262561000_2013.apr17_1.bcr2013009069.3","first-page":"30","article-title":"Pulmonary nocardiosis in human immunodeficiency virus infection: a tuberculosis mimic","volume":"2013","author":"Subhash","year":"2001","journal-title":"J Postgrad Med"},{"key":"2025082802262561000_2013.apr17_1.bcr2013009069.4","unstructured":"Winn W Allen S Janda W . eds. 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