{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:24:00Z","timestamp":1756383840830,"version":"3.40.4"},"reference-count":12,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>In primary amyloidosis (AL), a fibrillar protein (amyloid light chain) is deposited in many organs; however, it is rare to have involvement of the vertebral bodies. Multiple myeloma is a well-known systemic amyloid disease that frequently has vertebral involvement. However, the pathology of vertebral involvement of these two clinical entities differs significantly. We report a patient with L4 vertebral collapse because of primary AL, causing neurological compromise that improved with surgical treatment. Deposition of amyloid and following demineralisation caused the vertebral collapse. Primary AL needs to be taken into consideration as a cause of pathological vertebral fracture.<\/jats:p>","DOI":"10.1136\/bcr-2013-009075","type":"journal-article","created":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T06:21:04Z","timestamp":1370067664000},"page":"bcr2013009075","source":"Crossref","is-referenced-by-count":2,"title":["Vertebra collapse due to primary amyloidosis causing neurological compromise"],"prefix":"10.1136","volume":"2013","author":[{"given":"Hiroyuki","family":"Yoshihara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenya","family":"Nojiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Yabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Takahata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,5,31]]},"reference":[{"key":"2025042708075401000_2013.may31_1.bcr2013009075.1","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1136\/pgmj.62.733.1037","article-title":"Destructive bone lesions in primary amyloidosis","volume":"2013","author":"Kramer","year":"1986","journal-title":"Postgrad Med J"},{"key":"2025042708075401000_2013.may31_1.bcr2013009075.2","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1056\/NEJM199709253371306","article-title":"The systemic amyloidosis","volume":"2013","author":"Falk","year":"1997","journal-title":"N Engl J Med"},{"key":"2025042708075401000_2013.may31_1.bcr2013009075.3","first-page":"665","article-title":"Amyloidosis: clinical and laboratory features in 229 cases","volume":"2013","author":"Kyle","year":"1983","journal-title":"Mayo Clin Proc"},{"key":"2025042708075401000_2013.may31_1.bcr2013009075.4","unstructured":"Kyle RA Rajkumar SV . Plasma cell disorders. In: Goldman L Ausiello D , eds. Cecil textbook of medicine. 22nd edn. Philadelphia: W.B. 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