{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T12:05:18Z","timestamp":1768737918513,"version":"3.49.0"},"reference-count":9,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 21-year-old man presented to eye casualty complaining of altered vision associated with headache and vomiting upon waking. Clinical examination was unremarkable except for a right-sided homonymous hemianopia. The MRI scan of the brain revealed a space occupying lesion within the occipital lobe and MR spectroscopy highlighted this to be inflammatory in nature, most likely a tumefactive demyelinating lesion (TDL). Lumbar puncture displayed positive oligoclonal bands. The patient was managed conservatively and made a full recovery, with normal visual fields recorded after a 3\u2005month follow-up. This is a case of a TDL manifesting itself as an unusual cause of homonymous hemianopia; misdiagnosis of TDL is common and potentially damaging to the patient.<\/jats:p>","DOI":"10.1136\/bcr-2013-009363","type":"journal-article","created":{"date-parts":[[2013,6,28]],"date-time":"2013-06-28T11:42:19Z","timestamp":1372419739000},"page":"bcr2013009363","source":"Crossref","is-referenced-by-count":2,"title":["Tumefactive demyelination: an unusual cause of a spontaneously resolving homonymous hemianopia"],"prefix":"10.1136","volume":"2013","author":[{"given":"R A","family":"Dwivedi","sequence":"first","affiliation":[{"name":"Royal Liverpool & Broadgreen University Hospitals Trust, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R E","family":"Dwivedi","sequence":"additional","affiliation":[{"name":"Royal Liverpool & Broadgreen University Hospitals Trust, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Durnian","sequence":"additional","affiliation":[{"name":"Royal Liverpool & Broadgreen University Hospitals Trust, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C A","family":"Young","sequence":"additional","affiliation":[{"name":"The Walton Centre NHS Foundation Trust, Fazakerley, Liverpool, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,6,21]]},"reference":[{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.1","first-page":"69","article-title":"Case series: tumefactive demyelinating lesions: a diagnostic challenge","volume":"2013","author":"Fallah","year":"2010","journal-title":"Can J Surg"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.2","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1093\/brain\/awn098","article-title":"Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis","volume":"2013","author":"Lucchinetti","year":"2008","journal-title":"Brain"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.3","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1086\/656812","article-title":"Tumefactive demyelination-an unusual nuerological presentation of HIV","volume":"2013","author":"Uriel","year":"2010","journal-title":"Clin Infect Dis"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.4","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/BF00588163","article-title":"Multiple sclerosis masquerading as a mass lesion","volume":"2013","author":"Giang","year":"1992","journal-title":"Neuroradiology"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.5","first-page":"1378","article-title":"Proton MR spectroscopy of tumefactive demyelinating lesions","volume":"2013","author":"Saindane","year":"2002","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.6","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1148\/radiol.2512072071","article-title":"Distinguishing tumefactive demyelinating lesions from glioma or central nervous lymphoma: added value of unenhanced CT compared with conventional contrast-enhanced MR imaging","volume":"2013","author":"Kim","year":"2009","journal-title":"Radiology"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.7","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1212\/WNL.58.8.1147","article-title":"MRI techniques to monitor MS evolution: the present and the future","volume":"2013","author":"Filippi","year":"2002","journal-title":"Neurology"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.8","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1259\/bjr\/85069069","article-title":"Use of serial proton magnetic resonance spectroscopy to differentiate low grade glioma from tumefactive plaque in a patient with multiple sclerosis","volume":"2013","author":"Butteriss","year":"2003","journal-title":"Br J Radiol"},{"key":"2025082800250712000_2013.jun21_1.bcr2013009363.9","first-page":"363705","article-title":"Multiple large tumefactive MS plaques in a young man. A diagnostic enigma and therapeutic challenge","volume":"2013","author":"Kalani","year":"2012","journal-title":"Case Rep Radiol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-009363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:25:15Z","timestamp":1756365915000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-009363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,21]]},"references-count":9,"alternative-id":["10.1136\/bcr-2013-009363"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-009363","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,21]]}}}