{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:40:06Z","timestamp":1756291206103,"version":"3.44.0"},"reference-count":5,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Eosinophilic granulomatosis with polyangiitis is usually characterised by asthma, allergic rhinitis and peripheral eosinophilia. Presentations can vary greatly especially when there is cardiac involvement as demonstrated in these two case reports. Patient A initially presented to casualty with severe sinus pain and was diagnosed with severe sinonasal polyposis. After routine nasal polypectomy he had a cardiac arrest and was transferred to intensive care. Patient B presented to his general practitioner with a 4-week history of breathlessness, joint pain and a rash resulting in admission to hospital. Both patients had significant eosinophilia on routine bloods. High-sensitivity troponin T levels were raised in both; however, patient B's was significantly higher. Patient A had a large pericardial effusion on echo, the aspirate of which revealed numerous eosinophils. Patient B's echo was normal. Patient A's cardiac MRI was normal while Patient B's revealed myocarditis. Both were successfully treated with intravenous methylprednisolone and cyclophosphamide.<\/jats:p>","DOI":"10.1136\/bcr-2013-009394","type":"journal-article","created":{"date-parts":[[2013,7,13]],"date-time":"2013-07-13T01:43:19Z","timestamp":1373679799000},"page":"bcr2013009394","source":"Crossref","is-referenced-by-count":5,"title":["Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis"],"prefix":"10.1136","volume":"2013","author":[{"given":"Neil","family":"McAleavey","sequence":"first","affiliation":[{"name":"Department of Rheumatolgoy, Musgrave Park Hospital, Belfast, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Auleen","family":"Millar","sequence":"additional","affiliation":[{"name":"Department of Rheumatolgoy, Musgrave Park Hospital, Belfast, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian","family":"Pendleton","sequence":"additional","affiliation":[{"name":"Department of Rheumatolgoy, Musgrave Park Hospital, Belfast, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,7,12]]},"reference":[{"key":"2025082703213665000_2013.jul12_1.bcr2013009394.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/art.37715","article-title":"2012 revised International Chapel Hill Consensus Conference nomenclature of vasculitides","volume":"2013","author":"Jennette","year":"2013","journal-title":"Arthritis Rheum"},{"key":"2025082703213665000_2013.jul12_1.bcr2013009394.2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1097\/MD.0b013e3181af35a5","article-title":"Cardiac involvement in Churg-Strauss syndrome: impact of endomyocarditis","volume":"2013","author":"Neumann","year":"2009","journal-title":"Medicine (Baltimore)"},{"key":"2025082703213665000_2013.jul12_1.bcr2013009394.3","first-page":"195","article-title":"Randomised controlled trial of daily oral versus pulse cyclophosphamide for induction of remission in ANCA-associated systemic vasculitis","volume":"2013","author":"De Groot","year":"2005","journal-title":"Kidney Blood Press Res"},{"key":"2025082703213665000_2013.jul12_1.bcr2013009394.4","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1002\/art.27263","article-title":"Cardiac involvement in Churg-Strauss syndrome","volume":"2013","author":"Dennert","year":"2010","journal-title":"Arthritis Rheum"},{"key":"2025082703213665000_2013.jul12_1.bcr2013009394.5","doi-asserted-by":"crossref","first-page":"534","DOI":"10.2169\/internalmedicine.31.534","article-title":"Allergic granulomatosis and angiitis with severe cardiac disease: a case in which cardiac function was extremely improved by long-term steroid therapy","volume":"2013","author":"Takahashi","year":"1992","journal-title":"Int Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-009394","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:21:43Z","timestamp":1756290103000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-009394"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,12]]},"references-count":5,"alternative-id":["10.1136\/bcr-2013-009394"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-009394","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,7,12]]}}}