{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:28:52Z","timestamp":1787678932644,"version":"build-2784847793"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>On review of past 10\u2005years medical records, we could find four typical cases of porphyria with rare ocular manifestations. Cases 1, 2 and 4 have presented with features suggestive of acute scleritis. Based on clinical, biochemical and dermatological evaluation, all these three cases were diagnosed to have congenital erythropoietic porphyria. Case 1 was initially managed with scleral patch graft which on subsequent melt was managed with double layered amniotic membrane grafting along with conjunctival advancement and lateral paramedian tarsorrhaphy in both the eyes. Cases 2 and 4 were managed conservatively with artificial tear drops and general protective measures. Case 3 was presented with multiple failed grafts due to repeated ulceration and infection. Owing to multiple failed grafts, Boston keratoprosthesis was done and the patient is doing well with stable kertaoprosthesis at the last follow-up visit.<\/jats:p>","DOI":"10.1136\/bcr-2013-009496","type":"journal-article","created":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T12:55:26Z","timestamp":1369313726000},"page":"bcr2013009496","source":"Crossref","is-referenced-by-count":6,"title":["Porphyria: varied ocular manifestations and management"],"prefix":"10.1136","volume":"2013","author":[{"given":"Alok","family":"Sati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virender S","family":"Sangwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayan","family":"Basu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,5,22]]},"reference":[{"key":"2025042708023142000_2013.may22_1.bcr2013009496.1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1046\/j.1442-9071.2000.00330.x","article-title":"Congenital porphyria with necrotizing Scleritis in a 9-year-old child","volume":"2013","author":"Venkatesh","year":"2000","journal-title":"Clin \u00a0Exp Ophthalmol"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.2","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/0002-9394(81)90294-4","article-title":"Cicatricial ectropion and lacrimal obstruction associated with the sclerodermoid variant of porphyria cutanea tarda","volume":"2013","author":"Sober","year":"1981","journal-title":"Am J Ophthalmol"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.3","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1136\/bjo.76.10.592","article-title":"Photodamage of the conjunctiva in patients with porphyria cutanea tarda","volume":"2013","author":"Hammer","year":"1992","journal-title":"Br J Ophthalmol"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.4","doi-asserted-by":"crossref","unstructured":"Sati A Sangwan VS Basu S . Boston keratoprosthesis for visual rehabilitation in porphyria cutanea tarda. BMJ Case Rep 2013 Feb 1; 2013.","DOI":"10.1136\/bcr-2012-008267"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.5","first-page":"530","article-title":"Acute scleritis as a manifestation of congenital erythropoietic porphyria","volume":"2013","author":"Veenashree","year":"2012","journal-title":"Cornea"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.6","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1097\/ICO.0b013e31817e905a","article-title":"Ocular complications in 2 cases with porphyria","volume":"2013","author":"Altiparmak","year":"2008","journal-title":"Cornea"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.7","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/sj.eye.6701362","article-title":"Sight threatening complications in porphyria cutanea tarda","volume":"2013","author":"Zaborowski","year":"2004","journal-title":"Eye"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.8","unstructured":"Meyer UA . Porphyria. In: Braunwald E Issebacher KJ Petersdorf RG , et al. eds. Harrison's principles of internal medicine. 13th edn. New York: McGraw-Hill, 1994:2073\u20139."},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.9","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1016\/j.cgh.2006.11.017","article-title":"Porphyria cutanea tarda","volume":"2013","author":"Yachimski","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2025042708023142000_2013.may22_1.bcr2013009496.10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/ICO.0b013e3181e458fa","article-title":"Scleral necrosis in a patient with congenital erythropoietic purpura","volume":"2013","author":"Siddique","year":"2011","journal-title":"Cornea"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-009496","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T15:02:38Z","timestamp":1745766158000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-009496"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,22]]},"references-count":10,"alternative-id":["10.1136\/bcr-2013-009496"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-009496","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,22]]}}}