{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:02:30Z","timestamp":1790514150066,"version":"4.1.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Cerebral venous thrombosis (CVT) has usually been ascribed to prothrombotic conditions, oral contraceptives, pregnancy, malignancy, infection, head injury or mechanical precipitants. The case reported here illustrates two rare causes of CVT observed in the same patient: the presence of antiphospholipid antibodies associated with an asymptomatic cryptogenic organising pneumopathy (COP) which were considered the origin of the venous cerebral thrombosis and heparin-induced thrombocytopenia (HIT) which was responsible for the worsening of the thrombosis observed a few days after the introduction of treatment. Moreover, we provide here additional positive experience in the treatment of both, CVT and HIT, by fondaparinux with bridging to warfarin given their successful evolution under this anticoagulant option.<\/jats:p>","DOI":"10.1136\/bcr-2013-009500","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T03:04:30Z","timestamp":1373425470000},"page":"bcr2013009500","source":"Crossref","is-referenced-by-count":9,"title":["Cerebral venous thrombosis due to cryptogenic organising pneumopathy with antiphospholipid syndrome worsened by heparin-induced thrombocytopenia"],"prefix":"10.1136","volume":"2013","author":[{"given":"J","family":"Hsieh","sequence":"first","affiliation":[{"name":"Department of Neurology, Geneva University Hospital, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Kuzmanovic","sequence":"additional","affiliation":[{"name":"Department of Neurology, Geneva University Hospital, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M I","family":"Vargas","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, Geneva University Hospitals, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I","family":"Momjian-Mayor","sequence":"additional","affiliation":[{"name":"Department of Neurology, Geneva University Hospital, Geneva, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,7,9]]},"reference":[{"key":"2025082623113997000_2013.jul08_2.bcr2013009500.1","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1136\/bmj.314.7083.796","article-title":"Replacement therapy and risk of venous thromboembolism: population based case\u2014control study","volume":"2013","author":"P\u00e9rez 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