{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T18:16:22Z","timestamp":1788891382034,"version":"build-2803163510"},"reference-count":29,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>IgG4-related disease (IgG4RD) is a chronic recurring fibro-inflammatory pathology that is considered to be of autoimmune origin. Histopathology is considered to be the gold standard method for diagnosis. IgG4RD affects multiple organs. IgG4RD was first identified in the pancreas and was called autoimmune pancreatitis (AIP). During the following years, the disease spectrum was expanded and it was realised that the extrapancreatic lesions can precede, coexist or appear after the diagnosis of AIP. At present, several illnesses such as Mikulicz disease, K\u00fcttner tumour, multifocal fibrosclerosis, etc, are considered to be part of the IgG4RD spectrum. The symptoms of the disease tend to appear over months and years and diagnosis is achieved on average 13.5\u2005months (4\u201360\u2005months) after the onset. The purpose of this report was to provide information about a case that was sadly fatal but that permitted a complete histopathological study of the damaged tissues.<\/jats:p>","DOI":"10.1136\/bcr-2013-009636","type":"journal-article","created":{"date-parts":[[2013,5,3]],"date-time":"2013-05-03T07:52:45Z","timestamp":1367567565000},"page":"bcr2013009636","source":"Crossref","is-referenced-by-count":8,"title":["IgG4-related multiorgan disease: report of the first autopsy case"],"prefix":"10.1136","volume":"2013","author":[{"given":"Minerva Lazos","family":"Ochoa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belem","family":"Gabi\u00f1o L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ra\u00fal Romero","family":"Cabello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ra\u00fal Romero","family":"Feregrino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,5,2]]},"reference":[{"key":"2025042707483146000_2013.may02_1.bcr2013009636.1","first-page":"43","article-title":"IgG 4- related disease","volume":"2013","author":"Hirabayashi","year":"2012","journal-title":"Pathologica"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.2","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1007\/BF02232341","article-title":"Chronic inflammatory sclerosis of the pancreas\u2014an autonomous pancreatic disease?","volume":"2013","author":"Sarles","year":"1961","journal-title":"Am J Dig Dis"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.3","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0046-8177(91)90087-6","article-title":"Lymphoplasmacytic sclerosing pancreatitis with cholangitis: a variant of primary sclerosing cholangitis extensively involving pancreas","volume":"2013","author":"Kawaguchi","year":"1991","journal-title":"Hum Pathol"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.4","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1056\/NEJM200103083441005","article-title":"High serum IgG4 concentrations in patients with sclerosing pancreatitis","volume":"2013","author":"Hamano","year":"2001","journal-title":"N Engl J Med"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.5","doi-asserted-by":"crossref","first-page":"2811","DOI":"10.1111\/j.1572-0241.2003.08758.x","article-title":"Autoimmune pancreatitis is a systemic autoimmune disease","volume":"2013","author":"Kamisawa","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/s10165-011-0508-6","article-title":"A novel clinical entity, IgG4 related disease (IgG4RD): general concept and details","volume":"2013","author":"Umehara","year":"2012","journal-title":"Mod Rheumatol"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.7","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/01.mpa.0000167000.11889.3a","article-title":"Clinicopathological features of autoimmune pancreatitis in relation to elevation of serum IgG4","volume":"2013","author":"Kamisawa","year":"2005","journal-title":"Pancreas"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.8","first-page":"15","article-title":"IgG4 related sclerosing disease, an emerging entity: a review of a multi-system disease","volume":"2013","author":"Mukul","year":"2012","journal-title":"Yonsei Med J"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.9","first-page":"588","article-title":"Benign lymphadenopathies","volume":"2013","author":"Weiss","year":"2013","journal-title":"Mod Pathol"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.10","first-page":"113","article-title":"IgG4 related sclerosing disease","volume":"2013","author":"Kamisawa","year":"2009","journal-title":"Rhinsho Byori"},{"key":"2025042707483146000_2013.may02_1.bcr2013009636.11","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.revmed.2011.08.012","article-title":"IgG4 related systemic disease: emergence of a new systemic disease? 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