{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T22:30:06Z","timestamp":1784673006464,"version":"3.55.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>This is a case report highlighting the influence that antimicrobials (clarithromycin in particular) can have on one's mental state. We discuss the case of a middle-aged woman who presented to an acute admissions unit under Irish Mental Health Act for involuntary admission because of concerns expressed by her family and general practitioner regarding a recent change in behaviour and onset of irritable mood. This lady was diagnosed with an episode of mania that was thought to be precipitated by a combination of psychosocial stressors, recent discontinuation of psychotropic medication and complicated by a recent course of clarithromycin.<\/jats:p>","DOI":"10.1136\/bcr-2013-009659","type":"journal-article","created":{"date-parts":[[2013,7,6]],"date-time":"2013-07-06T07:03:13Z","timestamp":1373094193000},"page":"bcr2013009659","source":"Crossref","is-referenced-by-count":5,"title":["The potential for antimicrobials to adversely affect mental state"],"prefix":"10.1136","volume":"2013","author":[{"given":"Leona","family":"Lally","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Mannion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,7,5]]},"reference":[{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00004714-200202000-00012","article-title":"Antimicrobial induced mania (antibiomania): a review","volume":"2013","author":"Abouesh","year":"2002","journal-title":"J Clin Psychopharmacol"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0272-6386(96)90043-8","article-title":"Clarithromycin-associated visual hallucinations in a patient with chronic renal failure on continuous ambulatory peritoneal dialysis","volume":"2013","author":"Steinman","year":"1996","journal-title":"Am J Kidney Dis"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.3","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1093\/clinids\/20.6.1563","article-title":"Clarithromycin-induced mania in two patients with AIDS","volume":"2013","author":"Nightingale","year":"1995","journal-title":"Clin Infect Dis"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.4","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1093\/clinids\/22.3.595","article-title":"Mania due to clarithromycin therapy in a patient who was not infected with HIV","volume":"2013","author":"Cone","year":"1996","journal-title":"Clin Infect Dis"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.5","first-page":"66","article-title":"Acute manic psychosis induced by triple therapy for H Pylori","volume":"2013","author":"Neff","year":"2002","journal-title":"J Am Board Fam Practise"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.6","first-page":"325","article-title":"Case of mania due to prednisolone-clarithromycin interaction","volume":"2013","author":"Finkenbine","year":"1998","journal-title":"Gen Hosp Psychiatry"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.7","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1176\/ajp.155.11.1626","article-title":"Clarithromycin-induced mania","volume":"2013","author":"Abouesh","year":"1998","journal-title":"Am J Psychiatry"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.8","doi-asserted-by":"crossref","unstructured":"Ortiz-Dominguez A Berlanga C Gutierrez-Mora D . A case of clarithromycin-induced mania. Int J Neuropsychopharmacol 2004;:99\u2013100.","DOI":"10.1017\/S1461145703003882"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.9","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1093\/jac\/32.4.627","article-title":"Clarithromycin lacks bactericidal activity in CSF in experimental meningitis","volume":"2013","author":"Schmidt","year":"1993","journal-title":"J Antimicrob Chemother"},{"key":"2025042708300994000_2013.jul05_1.bcr2013009659.10","first-page":"70","article-title":"Clarithromycin-induced acute psychosis in peptic ulcer disease","volume":"2013","author":"Gomez-Gil","year":"1999","journal-title":"Eur J Clin Microbiol Infect Dis"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-009659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T15:30:22Z","timestamp":1745767822000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-009659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,5]]},"references-count":10,"alternative-id":["10.1136\/bcr-2013-009659"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-009659","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,5]]}}}