{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T11:15:29Z","timestamp":1759058129068,"version":"3.40.4"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>We describe a 79-year-old gentleman with a longstanding history of chronic lymphocytic leukaemia who presented with subacute onset of cholestatic jaundice. Comprehensive review of the patient's data and medications failed to reveal any obvious causes. Exhaustive testing including abdominal CT and magnetic resonance cholangiopancreatography failed to reveal any obstruction. A liver biopsy demonstrated scattered non-caseating granulomas. The patient was diagnosed with granulomatous hepatitis and treated with oral steroids and eventually improved. It was thought to be due to paraneoplastic cholestasis as an extrahepatic manifestation of non-Hodgkin's lymphoma.<\/jats:p>","DOI":"10.1136\/bcr-2013-009714","type":"journal-article","created":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T12:55:26Z","timestamp":1369313726000},"page":"bcr2013009714","source":"Crossref","is-referenced-by-count":5,"title":["Non-Hodgkin\u2019s lymphoma: a cause of paraneoplastic cholestasis"],"prefix":"10.1136","volume":"2013","author":[{"given":"Zaid","family":"Alirhayim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herman","family":"Dyal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulqader","family":"Alarhayem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vijayalakshmi","family":"Donthireddy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,5,22]]},"reference":[{"key":"2025042708010962000_2013.may22_1.bcr2013009714.1","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1002\/bjs.4119","article-title":"Non-Hodgkin lymphoma presenting with obstructive jaundice","volume":"2013","author":"Ravindra","year":"2003","journal-title":"Br J Surg"},{"key":"2025042708010962000_2013.may22_1.bcr2013009714.2","doi-asserted-by":"crossref","unstructured":"Forde K Kaplan DE . Cholestatic liver disease related to systemic disorders . In: Kindor KD, Talwalkar JA, eds. Cholestatic liver disease. New York: Humana Press, 2008:135\u201353.","DOI":"10.1007\/978-1-59745-118-5_8"},{"key":"2025042708010962000_2013.may22_1.bcr2013009714.3","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1111\/j.1572-0241.2001.05280.x","article-title":"Jaundice caused by a clinically undetectable T-cell lymphoma infiltrating the sphincter of Oddi","volume":"2013","author":"Weinstock","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"2025042708010962000_2013.may22_1.bcr2013009714.4","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3816\/CLM.2006.n.044","article-title":"Idiopathic cholestasis as a paraneoplastic phenomenon in Hodgkin's lymphoma","volume":"2013","author":"Barta","year":"2006","journal-title":"Clin Lymphoma Myeloma"},{"key":"2025042708010962000_2013.may22_1.bcr2013009714.5","first-page":"940","article-title":"Extrahepatic Hodgkin's disease and cholestasis","volume":"2013","author":"Warner","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"2025042708010962000_2013.may22_1.bcr2013009714.6","first-page":"99","article-title":"Intrahepatic cholestasis and biliary cirrhosis associated with extrahepatic Hodgkin's disease","volume":"2013","author":"Jansen","year":"1994","journal-title":"Neth J \u00a0Med"},{"key":"2025042708010962000_2013.may22_1.bcr2013009714.7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3816\/CLM.2004.n.007","article-title":"Paraneoplastic manifestations of lymphoma","volume":"2013","author":"Hagler","year":"2004","journal-title":"Clin Lymphoma"},{"key":"2025042708010962000_2013.may22_1.bcr2013009714.8","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1046\/j.1440-1746.1999.01982.x","article-title":"Inflammation induced cholestasis","volume":"2013","author":"Trauner","year":"1999","journal-title":"J Gastroenterol Hepatol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-009714","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,27]],"date-time":"2025-04-27T15:01:21Z","timestamp":1745766081000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-009714"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,22]]},"references-count":8,"alternative-id":["10.1136\/bcr-2013-009714"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-009714","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,5,22]]}}}