{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T09:15:23Z","timestamp":1792660523157,"version":"4.5.0"},"reference-count":11,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 59-year-old man presented with hypohydrosis in his left upper extremity and left hand, and experienced difficulty in gripping the steering wheel while driving. One year prior to admission, he had felt pain and\/or paresthesias in his left anterior chest, left shoulder area and left periaxillar area, which corresponded to involvement of dermatomes in T1\u2013T3. He was diagnosed with Horner's syndrome caused by lung tumour, which was located at the apical posterior wall along with the second to fourth ribs. The tumour interrupted sympathetic neurons at the T1\u2013T4 level. The degree of hypohydrosis was successfully evaluated by the starch\u2013iodine technique, dermal thermography and a skin surface hygrometer. After radiation therapy, hypohydrosis and pain or paresthesias improved partially, and he was discharged uneventfully.<\/jats:p>","DOI":"10.1136\/bcr-2013-009732","type":"journal-article","created":{"date-parts":[[2013,5,25]],"date-time":"2013-05-25T02:03:44Z","timestamp":1369447424000},"page":"bcr2013009732","source":"Crossref","is-referenced-by-count":2,"title":["Evidence for hypohydrosis as clinical clue to diagnosis of Horner's syndrome"],"prefix":"10.1136","volume":"2013","author":[{"given":"Manabu","family":"Higaki","sequence":"first","affiliation":[{"name":"Kyorin University School of Medicine, Mitaka, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Kurai","sequence":"additional","affiliation":[{"name":"Kyorin University School of Medicine, Mitaka, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anri","family":"Ito","sequence":"additional","affiliation":[{"name":"Kyorin University School of Medicine, Mitaka, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Saraya","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Kyorin University, Mitaka, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,5,24]]},"reference":[{"key":"2025082803080316000_2013.may24_1.bcr2013009732.1","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1097\/00000441-198806000-00006","article-title":"One-step iodine starch method for direct visualization of sweating","volume":"2013","author":"Sato","year":"1988","journal-title":"Am J Med Sci"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.2","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1007\/s004150200079","article-title":"Johann Friedrich Horner (1831\u20131886)","volume":"2013","author":"van der Wiel","year":"2002","journal-title":"J Neurol"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.3","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1378\/chest.114.4.1215","article-title":"Unilateral segmental hyperhidrosis associated with pulmonary adenocarcinoma","volume":"2013","author":"Slabbynck","year":"1998","journal-title":"Chest"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.4","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.crad.2007.12.006","article-title":"Imaging of Horner's syndrome","volume":"2013","author":"George","year":"2008","journal-title":"Clin Radiol"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.5","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1111\/j.1444-0938.2007.00177.x","article-title":"Horner syndrome","volume":"2013","author":"Kong","year":"2007","journal-title":"Clin Exp Optom"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.6","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/S0002-9394(14)74924-4","article-title":"Evaluation of the causes and accuracy of pharmacologic localization in Horner's syndrome","volume":"2013","author":"Maloney","year":"1980","journal-title":"Am J Ophthalmol"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.7","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jaad.2010.01.043","article-title":"A case of lung cancer with unilateral anhidrosis and contralateral hyperhidrosis as the first clinical manifestation","volume":"2013","author":"Nishimura","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.8","first-page":"257","article-title":"Guess what! Unilateral anhidrosis: first clinical manifestation of bronchial carcinoma","volume":"2013","author":"Munoz-Perez","year":"2001","journal-title":"Eur J Dermatol"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.9","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/0007-0971(77)90130-9","article-title":"Localized sympathetic overactivity: an unusual complication of bronchogenic carcinoma","volume":"2013","author":"Jegarajah","year":"1977","journal-title":"Br J Dis Chest"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.10","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0022-5223(19)42462-8","article-title":"The reverse Horner syndrome","volume":"2013","author":"Cole","year":"1970","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2025082803080316000_2013.may24_1.bcr2013009732.11","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/00041327-200503000-00002","article-title":"Segmental facial anhidrosis and tonic pupils with preserved deep tendon reflexes: a novel autonomic neuropathy","volume":"2013","author":"Kalapesi","year":"2005","journal-title":"J Neuro Ophthalmol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-009732","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T10:08:15Z","timestamp":1756375695000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-009732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,24]]},"references-count":11,"alternative-id":["10.1136\/bcr-2013-009732"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-009732","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,24]]}}}