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Considering the hypothesis of the pigment dispersion syndrome pathogenesis in which a difference of pressures in the anterior and posterior chambers creates a posterior convexity of the iris leading to reverse pupillary block, iris touch and consequently causing pigment dispersion, we suggest that the presence of an iris coloboma, by equalising the pressures in the two chambers, prevented the onset of syndrome in that eye.<\/jats:p>","DOI":"10.1136\/bcr-2013-009733","type":"journal-article","created":{"date-parts":[[2013,5,23]],"date-time":"2013-05-23T12:55:26Z","timestamp":1369313726000},"page":"bcr2013009733","source":"Crossref","is-referenced-by-count":1,"title":["Iris coloboma in one eye and pigment dispersion syndrome in the fellow eye"],"prefix":"10.1136","volume":"2013","author":[{"given":"Virgilio","family":"Galvis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Tello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Valarezo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ang\u00e9lica M","family":"Prada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,5,22]]},"reference":[{"key":"2025042708014939000_2013.may22_1.bcr2013009733.1","first-page":"185","article-title":"Ocular colobomata","volume":"2013","author":"Onwochei","year":"2000","journal-title":"Surv Ophthalmol"},{"key":"2025042708014939000_2013.may22_1.bcr2013009733.2","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1111\/j.1442-9071.2009.01920.x","article-title":"Pigment dispersion syndrome and pigmentary glaucoma\u2014a major review","volume":"2013","author":"Niyadurupola","year":"2008","journal-title":"Clin Experiment Ophthalmol"},{"key":"2025042708014939000_2013.may22_1.bcr2013009733.3","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1001\/archopht.1979.01020020235011","article-title":"Pigmentary dispersion and glaucoma. 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