{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:17:22Z","timestamp":1790234242281,"version":"4.1.0"},"reference-count":5,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>\u03b3-Benzene hexachloride is a commonly used insecticide of organochlorine group. Notable toxic effects include seizures, ataxia, confusion and other central nervous system dysfunction. A 30-year-old male farmer with suicidal ingestion of \u03b3-benzene hexachloride poison developed acute intrinsic renal failure with azotaemia and diminished urine output along with features of acute fulminate liver failure. Renal function recovered with haemodialysis and liver parameters gradually normalised with time. As per our knowledge simultaneous acute hepatic and kidney injury associated with \u03b3-benzene hexachloride poison is never reported in humans. The exact pathophysiology of this life-threatening complication is an enigma. However, oxidative stress has been postulated as a contributory factor as suggested in animal studies. Conservative management with successful outcome in our case stresses on the impact of watchful observation and aggressive management. He was discharged after 3\u2005weeks at stable condition and was healthy at 3\u2005months follow-up.<\/jats:p>","DOI":"10.1136\/bcr-2013-009851","type":"journal-article","created":{"date-parts":[[2013,8,7]],"date-time":"2013-08-07T08:58:17Z","timestamp":1375865897000},"page":"bcr2013009851","source":"Crossref","is-referenced-by-count":5,"title":["\u03b3-Benzene hexachloride poisoning leading to acute hepatorenal decompensation"],"prefix":"10.1136","volume":"2013","author":[{"given":"Rudrajit","family":"Paul","sequence":"first","affiliation":[{"name":"Department of General Medicine, Medical College Kolkata, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arunansu","family":"Talukdar","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Medical College Kolkata, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Medical College Kolkata, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gouranga","family":"Santra","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Medical College Kolkata, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,8,7]]},"reference":[{"key":"2025082801020269000_2013.aug07_1.bcr2013009851.1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1525-1470.2011.01519.x","article-title":"Lindane toxicity: a comprehensive review of the medical literature","volume":"2013","author":"Nolan","year":"2012","journal-title":"Pediatr Dermatol"},{"key":"2025082801020269000_2013.aug07_1.bcr2013009851.2","first-page":"182","article-title":"Pesticide poisoning","volume":"2013","author":"Goel","year":"2007","journal-title":"Natl Med J India"},{"key":"2025082801020269000_2013.aug07_1.bcr2013009851.3","first-page":"1050","article-title":"Acute lindane poisoning with development of muscle necrosis","volume":"2013","author":"Munk","year":"1977","journal-title":"Can Med Assoc J"},{"key":"2025082801020269000_2013.aug07_1.bcr2013009851.4","doi-asserted-by":"crossref","first-page":"80","DOI":"10.4103\/0971-4065.107222","article-title":"Benzene hexachloride poisoning with rhabdomyolysis and acute kidney injury","volume":"2013","author":"Shah","year":"2013","journal-title":"Indian J Nephrol"},{"key":"2025082801020269000_2013.aug07_1.bcr2013009851.5","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/0378-4274(90)90120-B","article-title":"Lindane induces nephropathy and renal accumulation of alpha 2u-globulin in male but not in female Fischer 344 rats or male NBR rats","volume":"2013","author":"Dietrich","year":"1990","journal-title":"Toxicol Lett"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-009851","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:02:09Z","timestamp":1756368129000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-009851"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,7]]},"references-count":5,"alternative-id":["10.1136\/bcr-2013-009851"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-009851","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,7]]}}}