{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:26:40Z","timestamp":1760984800273,"version":"3.40.4"},"reference-count":22,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Superficial siderosis of the central nervous system is a rare neurological disorder caused by deposits of haemosiderin on subplial brain matter. Characterised by a thin dark layer surrounding the brain stem, cerebellum and cortical fissures on the T2-weighted MRI, symptoms include sensorineural hearing loss and progressive gait ataxia. A specific aetiology for the blood in the subarachnoid space is identified in less than 50% of cases. While identification of a specific vascular defect allows for vascular repair, treatment options are limited for idiopathic superficial siderosis. Recently, a pilot safety study demonstrated promising results using an iron chelator, deferiprone. While this approach is promising, we present a potential serious complication of this therapy\u2014the first report of agranulocytosis in the treatment of superficial siderosis following deferiprone therapy.<\/jats:p>","DOI":"10.1136\/bcr-2013-010099","type":"journal-article","created":{"date-parts":[[2013,8,7]],"date-time":"2013-08-07T12:58:17Z","timestamp":1375880297000},"page":"bcr2013010099","source":"Crossref","is-referenced-by-count":14,"title":["Agranulocytosis with deferiprone treatment of superficial 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