{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:40:00Z","timestamp":1788306000743,"version":"build-2803163510"},"reference-count":23,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>The 47,XYY syndrome is an aneuploidy (abnormal number) of sex chromosomes, where a human male receives an extra Y chromosome, making 47 chromosomes instead of the usual 46. Individuals with 47,XYY are usually physically normal and tend to be tall and thin. They are not at increased risk of mental retardation and cardiovascular diseases. They may have speech delay, hyperactivity and normal\/decreased IQ level. Behavioural problems are not common in 47,XYY individuals. There have been reports that suggest the tooth-size increase in 47,XYY males is due to a direct genetic effect. The patient presented with multiple over-retained deciduous, unerupted permanent teeth and increased incidence of carious lesions may be attributed to decreased oral hygiene maintenance. The present article describes the medical and dental history along with the clinical management of oral health issues in an 18-year-old male patient with 47,XYY syndrome having normal physical structure and development.<\/jats:p>","DOI":"10.1136\/bcr-2013-010408","type":"journal-article","created":{"date-parts":[[2013,12,5]],"date-time":"2013-12-05T06:49:35Z","timestamp":1386226175000},"page":"bcr2013010408","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Oral health management of a patient with 47,XYY syndrome"],"prefix":"10.1136","volume":"2013","author":[{"given":"Altaf Hussain","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Preventive Dental Sciences, Salman bin Abdulaziz University, AlKharj, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B S","family":"Manjunatha","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, K M Shah Dental College & Hospital, Vadodara, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naif A","family":"Bindayel","sequence":"additional","affiliation":[{"name":"Division of Orthodontics, College of Dentistry, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Khounganian","sequence":"additional","affiliation":[{"name":"Division of Oral Biology and Pathology, College of Dentistry, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,12,5]]},"reference":[{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.1","first-page":"379","article-title":"Cytogenetic determinants of male fertility","volume":"14","author":"Martin","year":"2008","journal-title":"Hum Reprod"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.2","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-15"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.3","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1399-0004.1984.tb02013.x","article-title":"The development of four unselected 47,XYY boys","volume":"25","author":"Bender","year":"1984","journal-title":"Clin Genet"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.4","doi-asserted-by":"publisher","DOI":"10.1038\/2081351a0"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.5","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-1426"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.6","doi-asserted-by":"publisher","DOI":"10.1080\/03014469200002392"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.7","unstructured":"Ratcliffe SG Butler GE James M . 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Prophylaxis against infective endocarditis: antimicrobial prophylaxis against infective endocarditis in adults and children undergoing interventional procedures. London: National Institute for Health and Clinical Excellence, 2008."},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.14","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/S0140-6736(61)92459-X","article-title":"An XYY human male","volume":"2","author":"Sandberg","year":"1961","journal-title":"Lancet"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.15","unstructured":"Jones K . Smith's \u00a0recognizable patterns of human malformation. 5th edn. Elsevier Saunders, USA, 1997:66\u20138."},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-1809.1974.tb01843.x"},{"key":"2025082805090453000_2013.dec05_1.bcr2013010408.17","unstructured":"Buyse ME (ed). Chromosome X, chromosome XYY . In: Birth Defects Encyclopedia. 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