{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T16:10:24Z","timestamp":1764259824018,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Adrenal crisis is a group of clinical manifestation predominantly with hypotensive shock, electrolyte imbalance in a patient with adrenal insufficiency or in a patient who was abruptly withdrawn from glucocorticoid treatment acute myeloid leukaemia (AML) is one of the most common acute leukaemia in adults. Though the above diseases are commonly seen in individual patients, the coexistence of both conditions in the same patient is rare. We reported a 64-year-old African-American man with a history of bilateral deep vein thrombosis, who presented initially with fatigue, neutropenia and macrocytic anaemia. The patient developed a small bowel obstruction during his first hospital course, which resolved spontaneously with conservative management after an exploratory laparotomy. While waiting for his bone marrow biopsy, the patient developed hypotension, hyponatraemia and hyperkalaemia for which adrenal crisis was suspected. Later on, laboratory studies confirmed the diagnosis of primary adrenal insufficiency and the bone marrow was conclusive for AML.<\/jats:p>","DOI":"10.1136\/bcr-2013-010426","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T03:04:30Z","timestamp":1373425470000},"page":"bcr2013010426","source":"Crossref","is-referenced-by-count":8,"title":["Adrenal crisis in a patient with acute myeloid leukaemia"],"prefix":"10.1136","volume":"2013","author":[{"given":"Wang","family":"Li","sequence":"first","affiliation":[{"name":"Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Odessa, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikemefuna","family":"Okwuwa","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Odessa, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karla","family":"Toledo-Frazzini","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Odessa, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaaedin","family":"Alhomosh","sequence":"additional","affiliation":[{"name":"Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Odessa, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,7,9]]},"reference":[{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.1","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.ecl.2006.09.004","article-title":"Acute adrenal insufficiency","volume":"2013","author":"Bouillon","year":"2006","journal-title":"Endocrinol Metab Clin North Am"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.2","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/BF01707669","article-title":"Hemodynamic changes in acute adrenal insufficiency","volume":"2013","author":"Bouachour","year":"1994","journal-title":"Intensive Care Med"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.3","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1136\/pgmj.58.685.690","article-title":"Patients presenting with Addison's disease need not be pigmented","volume":"2013","author":"Barnett","year":"1982","journal-title":"Postgrad Med J"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.4","first-page":"379","article-title":"Patterns of leukemia incidence in the United States by subtype and demographic characteristics, 1997\u20132002","volume":"2013","author":"Yamamoto","year":"2008","journal-title":"Cancer Causes Control"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.5","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S0140-6736(12)61727-9","article-title":"Acute myeloid leukaemia in adults","volume":"2013","author":"Ferrara","year":"2013","journal-title":"Lancet"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.6","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1182\/blood-2009-03-209262","article-title":"The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes","volume":"2013","author":"Vardiman","year":"2009","journal-title":"Blood"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.7","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1046\/j.1365-2796.1997.00154.x","article-title":"Hyperkalaemia in acute leukaemia: a sign of adrenocortical insufficiency","volume":"2013","author":"Demiroglu","year":"1997","journal-title":"J Intern Med"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.8","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/j.1440-1754.2012.02556.x","article-title":"Rare presentation of shock and acute mesenteric ischaemia secondary to acute adrenal insufficiency in an 11-year-old male","volume":"2013","author":"Roldan-Martin","year":"2013","journal-title":"J Paediatr Child Health"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.9","first-page":"118","article-title":"Adrenal insufficiency masquerading as an acute abdomen","volume":"2013","author":"Laws","year":"2001","journal-title":"Hosp Med"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.10","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1111\/j.1440-1754.2004.00495.x","article-title":"Addison's disease presenting with an acute abdomen and complicated by cardiomyopathy","volume":"2013","author":"Wiltshire","year":"2004","journal-title":"J Paediatr Child Health"},{"key":"2025082700585836000_2013.jul08_2.bcr2013010426.11","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1148\/62.1.16","article-title":"Roentgenologic observations in Addison's disease; 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