{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:52:45Z","timestamp":1784688765430,"version":"3.55.0"},"reference-count":8,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>Neurofibroma is a benign tumour derived from the neural sheaths of peripheral nerves and composed of Schwann cells, fibroblast-like cells and intermediate cells. The usual clinical presentation of an oral neurofibroma is swelling. A 62-year-old woman was referred to our department of otorhinolaryngology with irritation and dysaesthesia of the lateral aspect of the tongue. The only finding was a slightly red area from which a biopsy was taken. The macroscopic findings observed by the surgeon were consistent with normal tongue tissue. The histopathological examination showed a small, rounded tumour closely approximated to an invagination of the surface epithelium and with a small lymphatic infiltrate. The tumour was a neurofibroma. A Schwannoma type B was considered but the presence of small nerves and positive neurofilament reaction favoured a neurofibroma. The patient had no other neurofibromas or skin lesions. At a 3-week follow-up visit all symptoms had resolved.<\/jats:p>","DOI":"10.1136\/bcr-2013-010440","type":"journal-article","created":{"date-parts":[[2013,10,8]],"date-time":"2013-10-08T08:38:06Z","timestamp":1381221486000},"page":"bcr2013010440","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Lingual neurofibroma causing dysaesthesia of the tongue"],"prefix":"10.1136","volume":"2013","author":[{"given":"Eva","family":"Lykke","sequence":"first","affiliation":[{"name":"Department of Otolaryngology of Head and Neck Surgery, Hilleroed Hospital, Hiller\u00f8d, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tove","family":"Noergaard","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospital of Copenhagen, Copenhagen east, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva Rye","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology \u2013 Head and Neck Surgery, Koege Hospital, Koege, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2013,10,8]]},"reference":[{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.1","unstructured":"Cawson RA . Luca's Pathology of tumors of the oral tissues. Churchill Livingstone, 1998."},{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.2","unstructured":"Gnepp DR . Diagnostic surgical pathology of the head and neck. Saunders Elsevier, 2009."},{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s00784-006-0096-6","article-title":"Sporadic and multiple neurofibromas in the head and neck region: a retrospective study of 33\u2005years","volume":"2013","author":"Marocchio","year":"2007","journal-title":"Clin Oral Invest"},{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/014556131109000205","article-title":"Isolated neurofibroma of the tongue presenting as a papilloangiomatous mass","volume":"2013","author":"Dutta","year":"2011","journal-title":"Ear Nose Throat J"},{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.5","doi-asserted-by":"crossref","first-page":"577","DOI":"10.3109\/00016357.2011.640286","article-title":"Clinicopathologic and immunohistochemical features of oral neurofibroma","volume":"2013","author":"Campos","year":"2012","journal-title":"Acta Odont Scand"},{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.6","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1590\/S1806-83242009000100008","article-title":"Retrospective analysis of oral peripheral nerve sheath tumors in Brazilians","volume":"2013","author":"Salla","year":"2009","journal-title":"Braz Oral Res"},{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.7","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S1607-551X(09)70339-0","article-title":"Neurofibroma of the lingual nerve: a case report","volume":"2013","author":"Wang","year":"2006","journal-title":"Kaohsiung J Med Sci"},{"key":"2025082700213751000_2013.oct08_1.bcr2013010440.8","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1097\/SCS.0b013e3181d7ae5a","article-title":"Isolated plexiform neurofibroma of the tongue","volume":"2013","author":"Sirinoglu","year":"2010","journal-title":"J Craniofac Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-010440","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:21:49Z","timestamp":1756279309000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-010440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,8]]},"references-count":8,"alternative-id":["10.1136\/bcr-2013-010440"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-010440","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,8]]}}}