{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:10:14Z","timestamp":1756289414472,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Reports"],"abstract":"<jats:p>A 62-year-old woman presented to the emergency department with malaise, lethargy and proximal muscle weakness. She had a similar presentation in childhood. A muscle biopsy was inconclusive, however, she was treated for a presumptive diagnosis of inflammatory myositis. In a second flare in childhood, she developed proximal muscle weakness and calcinosis cutis. A muscle biopsy was consistent with juvenile dermatomyositis. She was treated with corticosteroids, however, she relapsed again 1\u2005year later, requiring a prolonged course of corticosteroids, which led to remission and treatment was subsequently stopped. She remained well for 30\u2005years without any relapses, however, at the age of 40 she was diagnosed with malignant melanoma, treated with local excision and radiotherapy. She had a further period of 22\u2005years in good health, until her current presentation, with a relapse of dermatomyositis, 52\u2005years after the last flare. She is currently in remission following successful immunosuppressive therapy.<\/jats:p>","DOI":"10.1136\/bcr-2013-200008","type":"journal-article","created":{"date-parts":[[2013,9,2]],"date-time":"2013-09-02T05:33:45Z","timestamp":1378100025000},"page":"bcr2013200008","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Childhood dermatomyositis recurring in adulthood half a century later"],"prefix":"10.1136","volume":"2013","author":[{"given":"M","family":"Ismajli","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Whittington Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E","family":"Nikiphorou","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Addenbrooke's Hospital, Cambridge, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, St Albans Hospital, Hertfordshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2013,9,2]]},"reference":[{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.1","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1749-6632.2009.05119.x","article-title":"Dermatomyositis and polymyositis: clinical presentation, autoantibodies, and pathogenesis","volume":"2013","author":"Mammen","year":"2010","journal-title":"Ann N Y Acad Sci"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.2","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1084\/jem.20041367","article-title":"Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy","volume":"2013","author":"Casciola-Rosen","year":"2005","journal-title":"J Exp Med"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.3","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1097\/01.bor.0000245721.02512.77","article-title":"Cancer and myositis: new insights into an old association","volume":"2013","author":"Levine","year":"2006","journal-title":"Curr Opin Rheumatol"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.4","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/1529-0131(200003)43:3<541::AID-ANR9>3.0.CO;2-T","article-title":"Medium- and long-term functional outcomes in a multicenter cohort of children with juvenile dermatomyositis","volume":"2013","author":"Huber","year":"2000","journal-title":"Arthritis Rheum"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.5","first-page":"561","article-title":"Dermatomyositis\u2014a study of five cases","volume":"2013","author":"Kinney","year":"1940","journal-title":"Am J Pathol"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.6","first-page":"782","article-title":"Dermatomyositis in childhood with recurrence in adulthood: 2 cases","volume":"2013","author":"Touton","year":"1993","journal-title":"Ann Dermatol Venereol"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.7","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1136\/ard.44.5.356-b","article-title":"Unusual case of childhood dermatomyositis","volume":"2013","author":"Martini","year":"1985","journal-title":"Ann Rheum Dis"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.8","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1186\/ar2825","article-title":"Why are women predisposed to autoimmune rheumatic diseases","volume":"2013","author":"Oliver","year":"2009","journal-title":"Arthritis Res Ther"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.9","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2174\/1568013053005418","article-title":"Estrogen, immunity and autoimmune disease","volume":"2013","author":"Nalbandian","year":"2005","journal-title":"Curr Med Chem\u2014Immunol Endocr Metab Agents"},{"key":"2025082702511068000_2013.sep02_1.bcr2013200008.10","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0378-5122(00)00118-3","article-title":"Menopause, oestrogen and arthritis","volume":"2013","author":"Wluka","year":"2000","journal-title":"Maturitas"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2013-200008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:51:20Z","timestamp":1756288280000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2013-200008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,2]]},"references-count":10,"alternative-id":["10.1136\/bcr-2013-200008"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2013-200008","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2013,9,2]]}}}